(Q38153815)

29 August 2017

title

New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research (English)

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idiopathic pulmonary fibrosis

29 August 2017

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1 reference

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Eva Baroke

1

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29 August 2017

Jack Gauldie

series ordinal

2

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29 August 2017

Martin Kolb

series ordinal

3

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29 August 2017

publication date

1 October 2013

1 reference

Expert Review of Respiratory Medicine

29 August 2017

published in

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29 August 2017

volume

7

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29 August 2017

issue

5

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29 August 2017

page(s)

465-478

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The clinical course of patients with idiopathic pulmonary fibrosis

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Changes in clinical and physiologic variables predict survival in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

High-dose acetylcysteine in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Endothelin-1 and endothelin-3 induce chemotaxis and replication of pulmonary artery fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Fibroblasts and myofibroblasts: their source, function and role in disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Potential role of endothelin-1 in pulmonary fibrosis: from the bench to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

BUILD-3: a randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Treatment of idiopathic pulmonary fibrosis with etanercept: an exploratory, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Imatinib as a novel antifibrotic agent in bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Pharmacologic differentiation of inflammation and fibrosis in the rat bleomycin model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial/mesenchymal phenotypes: implications for treatment of fibrotic diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo-controlled trial results

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Anticoagulant therapy for idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Pirfenidone in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Targeting non-malignant disorders with tyrosine kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Protein kinase inhibitors in the treatment of pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Paradoxical roles for lysyl oxidases in cancer--a prospect

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Important roles for macrophage colony-stimulating factor, CC chemokine ligand 2, and mononuclear phagocytes in the pathogenesis of pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

The role of CCL12 in the recruitment of fibrocytes and lung fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Indomethacin suppresses the anti-proliferative effects of transforming growth factor-beta isoforms on fibroblast cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Re-evaluation of fibrogenic cytokines in lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Sequential changes of KL-6 in sera of patients with interstitial pneumonia associated with polymyositis/dermatomyositis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

KL-6, a human MUC1 mucin, promotes proliferation and survival of lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

High serum concentrations of surfactant protein A in usual interstitial pneumonia compared with non-specific interstitial pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Comparative study of KL-6, surfactant protein-A, surfactant protein-D, and monocyte chemoattractant protein-1 as serum markers for interstitial lung diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Increased levels of KL-6 and subsequent mortality in patients with interstitial lung diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Prognostic value of circulating KL-6 in idiopathic pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Prognostic value of immunohistochemical surfactant protein A expression in regenerative/hyperplastic alveolar epithelial cells in idiopathic interstitial pneumonias

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Matrix metalloproteinases in respiratory diseases: from pathogenesis to potential clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

The phylogenetically conserved molluscan chitinase-like protein 1 (Cg-Clp1), homologue of human HC-gp39, stimulates proliferation and regulates synthesis of extracellular matrix components of mammalian chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Raised human cartilage glycoprotein-39 plasma levels in patients with rheumatoid arthritis and other inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

A chitinase-like protein in the lung and circulation of patients with severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Plasma YKL-40: a potential new cancer biomarker?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Cells derived from the circulation contribute to the repair of lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Bone marrow-derived progenitor cells in pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Identification of annexin 1 as a novel autoantigen in acute exacerbation of idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Idiopathic pulmonary fibrosis related to endothelial injury and antiendothelial cell antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Localisation of a pulmonary autoantigen in cryptogenic fibrosing alveolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Role of the chemokine receptors CXCR3 and CCR4 in human pulmonary fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

CD8+ T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Systemic immune cell activation in a subgroup of patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Idiopathic pulmonary fibrosis-an epidemiological and pathological review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Inflammatory cell phenotyping of the pulmonary interstitium in idiopathic interstitial pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

CD28 down-regulation on circulating CD4 T-cells is associated with poor prognoses of patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Elevated matrilysin levels in bronchoalveolar lavage fluid do not distinguish idiopathic pulmonary fibrosis from other interstitial lung diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

Autoantibody to alanyl-tRNA synthetase in patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17476348.2013.838015

10.1586/17476348.2013.838015

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference