(Q38156717)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24174318%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia (English)

1 reference

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28 February 2020

0 references

1 reference

1

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28 February 2020

Lars Rönnstrand

series ordinal

3

1 reference

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28 February 2020

2

Nuzhat N Kabir

1 reference

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28 February 2020

publication date

31 October 2013

1 reference

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28 February 2020

1 reference

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28 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24174318%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

4

1 reference

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28 February 2020

page(s)

757

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https://scigraph.springernature.com/pub.10.1007/s12032-013-0757-7

28 February 2020

exact match

0 references

cites work

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Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner

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Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes

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Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70.

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A single point mutation in the V3 region affects protein kinase Calpha targeting and accumulation at cell-cell contacts

21 January 2018

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The PKCalpha-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals

21 January 2018

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PEP005 (ingenol mebutate) gel for the topical treatment of superficial basal cell carcinoma: results of a randomized phase IIa trial.

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Characterization of the interaction of ingenol 3-angelate with protein kinase C.

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Novel antileukemic compound ingenol 3-angelate inhibits T cell apoptosis by activating protein kinase Ctheta

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Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling

21 January 2018

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FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia

21 January 2018

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The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling

21 January 2018

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Deregulation of protein phosphatase expression in acute myeloid leukemia

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia

21 January 2018

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ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism.

21 January 2018

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Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

21 January 2018

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Targeting protein kinase C-alpha (PKC-alpha) in cancer with the phosphorothioate antisense oligonucleotide aprinocarsen

21 January 2018

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Mechanisms of apoptosis-induction by rottlerin: therapeutic implications for B-CLL.

21 January 2018

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A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C.

21 January 2018

1 reference

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Enzastaurin hydrochloride for lymphoma: reassessing the results of clinical trials in light of recent advances in the biology of B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0757-7

B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase C II

21 January 2018

1 reference

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PLC-γ activation is required for PDGF-βR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0757-7

Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2

21 January 2018

1 reference

12 December 2020

Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed phenotype of CaCo-2 cells.

1 reference

12 December 2020

Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells

1 reference

12 December 2020

Protein kinase C isoform expression in chronic lymphocytic leukemia: a potential target for therapy?

1 reference

12 December 2020

Membrane PKC-beta 2 protein expression predicts for poor response to chemotherapy and survival in patients with diffuse large B-cell lymphoma

1 reference

12 December 2020

Activation of protein kinase Calpha inhibits growth of pancreatic cancer cells via p21(cip)-mediated G(1) arrest.

1 reference

12 December 2020

Involvement of PKC-alpha in PDGF-mediated mitogenic signaling in human mesangial cells

1 reference

12 December 2020

Protein kinase C alpha and tumorigenesis of the endocrine gland

1 reference

12 December 2020

1 reference

12 December 2020

Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C.

1 reference

12 December 2020

Expression of three major protein kinase C isozymes in various types of human leukemic cells.

1 reference

12 December 2020

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain

1 reference

12 December 2020

Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.

1 reference

12 December 2020

New insights into the phenotype and cell derivation of B cell chronic lymphocytic leukemia

1 reference

12 December 2020

Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome

1 reference

12 December 2020

Invasive human pituitary tumors express a point-mutated alpha-protein kinase-C

1 reference

12 December 2020

Expression of PKC-beta or cyclin D2 predicts for inferior survival in diffuse large B-cell lymphoma

1 reference

12 December 2020

Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.

1 reference

12 December 2020

Translocation of protein kinase C-delta by PDGF in cultured vascular smooth muscle cells: inhibition by TGF-beta 1

1 reference

12 December 2020

Induction of the nuclear proto-oncogene c-fos by the phorbol ester TPA and v-H-Ras.

1 reference

12 December 2020

10.1007/S12032-013-0757-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24174318%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 February 2020

1008197168

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24174318%20AND%20SRC:MED&resulttype=core&format=json