(Q38169791)

30 August 2017

The diversity of soft tissue tumours with EWSR1 gene rearrangements: a review (English)

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30 August 2017

Cyril Fisher

1

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30 August 2017

6 November 2013

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30 August 2017

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30 August 2017

64

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30 August 2017

1

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30 August 2017

134-150

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The impact of translocations and gene fusions on cancer causation

30 August 2017

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Triggers for genomic rearrangements: insights into genomic, cellular and environmental influences

21 January 2018

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Biology of EWS/ETS fusions in Ewing's family tumors

21 January 2018

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Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumor

21 January 2018

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Molecular variants of the EWS-WT1 gene fusion in desmoplastic small round cell tumor.

21 January 2018

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A novel type of EWS-CHOP fusion gene in two cases of myxoid liposarcoma

21 January 2018

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A novel type of EWS-CHOP fusion gene in myxoid liposarcoma.

21 January 2018

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Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation

21 January 2018

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Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma.

21 January 2018

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Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).

21 January 2018

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Fusion of the EWSR1 and ATF1 genes without expression of the MITF-M transcript in angiomatoid fibrous histiocytoma

21 January 2018

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Angiomatoid fibrous histiocytoma: unusual sites and unusual morphology.

21 January 2018

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EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

21 January 2018

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Clear cell sarcoma of soft tissue: a clinicopathologic, immunohistochemical, and molecular analysis of 33 cases.

21 January 2018

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Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts).

21 January 2018

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Primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion: a new tumor entity.

21 January 2018

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EWSR1-POU5F1 fusion in soft tissue myoepithelial tumors. A molecular analysis of sixty-six cases, including soft tissue, bone, and visceral lesions, showing common involvement of the EWSR1 gene

21 January 2018

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Cutaneous syncytial myoepithelioma: clinicopathologic characterization in a series of 38 cases

21 January 2018

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EWSR1-CREB3L1 gene fusion: a novel alternative molecular aberration of low-grade fibromyxoid sarcoma

21 January 2018

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RNA sequencing identifies fusion of the EWSR1 and YY1 genes in mesothelioma with t(14;22)(q32;q12).

21 January 2018

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EWSR1-ATF1 fusion is a novel and consistent finding in hyalinizing clear-cell carcinoma of salivary gland.

21 January 2018

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EWSR1 genetic rearrangements in salivary gland tumors: a specific and very common feature of hyalinizing clear cell carcinoma

21 January 2018

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POU5F1, encoding a key regulator of stem cell pluripotency, is fused to EWSR1 in hidradenoma of the skin and mucoepidermoid carcinoma of the salivary glands.

21 January 2018

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Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation

21 January 2018

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Identification of an EWS-pseudogene using translocation detection by RT-PCR in Ewing's sarcoma.

21 January 2018

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Identification and characterization of the nuclear localization/retention signal in the EWS proto-oncoprotein

21 January 2018

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Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo

21 January 2018

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Dynamic subcellular localization of the Ewing sarcoma proto-oncoprotein and its association with and stabilization of microtubules

21 January 2018

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Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

21 January 2018

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Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

21 January 2018

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Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

21 January 2018

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Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins

21 January 2018

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Cabeza, a Drosophila gene encoding a novel RNA binding protein, shares homology with EWS and TLS, two genes involved in human sarcoma formation

21 January 2018

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Sarcomas: genetics, signalling, and cellular origins. Part 1: The fellowship of TET.

21 January 2018

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Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: alveolar soft part sarcoma

21 January 2018

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Updates on cytogenetics and molecular genetics of bone and soft tissue tumors: Ewing sarcoma and peripheral primitive neuroectodermal tumors

21 January 2018

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Specificity of TLS-CHOP rearrangement for classic myxoid/round cell liposarcoma: absence in predominantly myxoid well-differentiated liposarcomas

21 January 2018

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Malignant small cell tumor of the thoracopulmonary region in childhood.A distinctive clinicopathologic entity of uncertain histogenesis

21 January 2018

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Clinical features and outcomes in patients with extraskeletal Ewing sarcoma

21 January 2018

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Ewing sarcoma: clinical state-of-the-art

21 January 2018

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Soft tissue Ewing sarcoma--peripheral primitive neuroectodermal tumor with atypical clear cell pattern shows a new type of EWS-FEV fusion transcript

21 January 2018

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Advances in Ewing's sarcoma research: where are we now and what lies ahead?

21 January 2018

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A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

21 January 2018

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Complex rearrangement of chromosomes 19, 21, and 22 in Ewing sarcoma involving a novel reciprocal inversion-insertion mechanism of EWS-ERG fusion gene formation: a case analysis and literature review

21 January 2018

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Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma.

21 January 2018

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Usefulness of a monoclonal ERG/FLI1 antibody for immunohistochemical discrimination of Ewing family tumors

21 January 2018

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A new member of the ETS family fused to EWS in Ewing tumors

21 January 2018

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Ewing sarcoma-peripheral neuroectodermal tumor of the kidney with a FUS-ERG fusion transcript.

21 January 2018

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Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV.

21 January 2018

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The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology

21 January 2018

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EWSR1 is fused to POU5F1 in a bone tumor with translocation t(6;22)(p21;q12).

21 January 2018

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A novel zinc finger gene is fused to EWS in small round cell tumor

21 January 2018

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Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions

21 January 2018

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High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas.

21 January 2018

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The CIC-DUX4 fusion transcript is present in a subgroup of pediatric primitive round cell sarcomas.

21 January 2018

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Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation

21 January 2018

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Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event.

21 January 2018

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The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

21 January 2018

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Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.

21 January 2018

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Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G(1)regulatory genes.

21 January 2018

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Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.

21 January 2018

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EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

21 January 2018

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FOXM1 is an oncogenic mediator in Ewing Sarcoma

21 January 2018

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GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors

21 January 2018

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GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance

21 January 2018

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IGF1 is a common target gene of Ewing's sarcoma fusion proteins in mesenchymal progenitor cells.

21 January 2018

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Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival.

21 January 2018

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DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells

21 January 2018

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Vascular endothelial growth factor expression is up-regulated by EWS-ETS oncoproteins and Sp1 and may represent an independent predictor of survival in Ewing's sarcoma

21 January 2018

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EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

21 January 2018

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Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein

21 January 2018

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Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group

21 January 2018

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Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.

21 January 2018

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Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

21 January 2018

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Desmoplastic small round cell tumors of the paratesticular region. A report of six cases.

21 January 2018

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Desmoplastic small round cell tumor: I: a histopathologic study of 39 cases with emphasis on unusual histological patterns.

21 January 2018

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The EWS-WT1 gene fusion in desmoplastic small round cell tumor

21 January 2018

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Utility of sarcoma-specific fusion gene analysis in paraffin-embedded material for routine diagnosis at a specialist centre.

21 January 2018

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Myxoid liposarcoma--the frequency and the natural history of nonpulmonary soft tissue metastases

21 January 2018

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Myxoid/round cell liposarcoma of the extremities. A clinicopathologic study of 29 cases with particular attention to extent of round cell liposarcoma

21 January 2018

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The clinicopathologic spectrum of myxoid and round cell liposarcoma. A study of 95 cases

21 January 2018

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Combined morphologic and karyotypic study of 28 myxoid liposarcomas. Implications for a revised morphologic typing, (a report from the CHAMP Group).

21 January 2018

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Relevance of translocation type in myxoid liposarcoma and identification of a novel EWSR1-DDIT3 fusion

21 January 2018

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The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells

21 January 2018

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[Identification of genes over-expressed in myxoid/round cell liposarcoma. DNA microarray analysis and immunohistochemical correlation].

21 January 2018

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Skeletal and extraskeletal myxoid chondrosarcoma: a comparative clinicopathologic, ultrastructural, and molecular study.

21 January 2018

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Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors.

21 January 2018

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Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a case report with fine-needle aspiration biopsy, histopathology, electron microscopy, and cytogenetics

21 January 2018

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Extraskeletal myxoid chondrosarcoma: a light microscopic, immunohistochemical, ultrastructural and immuno-ultrastructural study indicating neuroendocrine differentiation

21 January 2018

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Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 18 cases

21 January 2018

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The EWSR1/NR4A3 fusion protein of extraskeletal myxoid chondrosarcoma activates the PPARG nuclear receptor gene.

21 January 2018

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A novel sarcoma with dual differentiation: clinicopathologic and molecular characterization of a combined synovial sarcoma and extraskeletal myxoid chondrosarcoma.

21 January 2018

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Tumors with EWSR1-CREB1 and EWSR1-ATF1 fusions: the current status

21 January 2018

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Angiosarcoma of the parotid gland with a t(12;22) translocation creating a EWSR1-ATF1 fusion: a diagnostic dilemma.

21 January 2018

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Angiomatoid malignant fibrous histiocytoma.A distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm

21 January 2018

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A rare mediastinal tumour presenting with systemic effects due to IL-6 and tumour necrosis factor (TNF) production

21 January 2018

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Primary intracerebral angiomatoid fibrous histiocytoma: report of a case with a t(12;22)(q13;q12) causing type 1 fusion of the EWS and ATF-1 genes.

21 January 2018

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Angiomatoid fibrous histiocytoma of bone: a calcifying sclerosing variant mimicking osteosarcoma.

21 January 2018

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Imaging characteristics of angiomatoid fibrous histiocytoma of bone

21 January 2018

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Fusion genes in angiomatoid fibrous histiocytoma.

21 January 2018

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Metastatic angiomatoid fibrous histiocytoma of the scalp, with EWSR1-CREB1 gene fusions in primary tumor and nodal metastasis

21 January 2018

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Clear cell sarcoma of tendons and aponeuroses, and osteoclast-rich tumour of the gastrointestinal tract with features resembling clear cell sarcoma of soft parts: a review and update

21 January 2018

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Clear cell sarcoma: the Roswell Park experience

21 January 2018

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Soft-tissue sarcomas in adults

21 January 2018

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Diagnosis of clear cell sarcoma by real-time reverse transcriptase-polymerase chain reaction analysis of paraffin embedded tissues: clinicopathologic and molecular analysis of 44 patients from the French sarcoma group.

21 January 2018

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Discovery of two novel EWSR1/ATF1 transcripts in four chimerical transcripts-expressing clear cell sarcoma and their quantitative evaluation.

21 January 2018

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Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.

21 January 2018

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Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene

21 January 2018

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Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics

21 January 2018

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Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium

21 January 2018

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Molecular diagnosis of clear cell sarcoma: detection of EWS-ATF1 and MITF-M transcripts and histopathological and ultrastructural analysis of 12 cases

21 January 2018

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The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma

21 January 2018

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Classification of clear-cell sarcoma as a subtype of melanoma by genomic profiling.

21 January 2018

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EWS-CREB1: a recurrent variant fusion in clear cell sarcoma--association with gastrointestinal location and absence of melanocytic differentiation.

21 January 2018

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EWS-ATF1 fusion transcripts in gastrointestinal tumors previously diagnosed as malignant melanoma

21 January 2018

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Malignant myxoid endobronchial tumour: a report of two cases with a unique histological pattern.

21 January 2018

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Soft tissue myoepithelioma: a case report

21 January 2018

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Myoepithelial tumors of soft tissue: a clinicopathologic and immunohistochemical study of 101 cases with evaluation of prognostic parameters

21 January 2018

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Myoepithelioma of the soft tissue of the head and neck: a case report and review of the literature

21 January 2018

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Malignant myoepithelial tumor of soft tissue: a report of two cases of the lower extremity and a review of the literature

21 January 2018

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Oral myoepithelioma of soft tissue origin: report of a new case and literature review

21 January 2018

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Malignant cutaneous glomus tumor presenting as a rapidly growing leg mass in a pregnant woman.

21 January 2018

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Benign myoepithelioma of the skin

21 January 2018

1 reference

Long-term survival and transmission of INI1-mutation via nonpenetrant males in a family with rhabdoid tumour predisposition syndrome

21 January 2018

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Loss of INI1 expression is characteristic of both conventional and proximal-type epithelioid sarcoma.

21 January 2018

1 reference

Primary myoepithelioma of bone: a report of 8 cases

21 January 2018

1 reference

Detection of a t(1;22)(q23;q12) translocation leading to an EWSR1-PBX1 fusion gene in a myoepithelioma.

21 January 2018

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t(19;22)(q13;q12) Translocation leading to the novel fusion gene EWSR1-ZNF444 in soft tissue myoepithelial carcinoma.

21 January 2018

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Ossifying Fibromyxoid Tumor of Soft Parts

21 January 2018

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Soft tissue tumors associated with EWSR1 translocation.

21 January 2018

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MUC4 Is a Sensitive and Extremely Useful Marker for Sclerosing Epithelioid Fibrosarcoma

21 January 2018

1 reference

EWSR1-CREB1 and EWSR1-ATF1 Fusion Genes in Angiomatoid Fibrous Histiocytoma

21 January 2018

1 reference

Angiomatoid Fibrous Histiocytoma: Pleomorphic Variant Associated with Multiplication of EWSR1-CREB1 Fusion Gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/HIS.12269

1 reference

30 August 2017

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PubMed ID

24320889