(Q38174018)

English

Lessons from the heart: mirroring electrophysiological characteristics during cardiac development to in vitro differentiation of stem cell derived cardiomyocytes.

scientific article published on 23 December 2013

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3 March 2020

Lessons from the heart: mirroring electrophysiological characteristics during cardiac development to in vitro differentiation of stem cell derived cardiomyocytes (English)

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3 March 2020

electrophysiology

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based on heuristic

inferred from title

Malin K B Jonsson

4

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3 March 2020

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Nikki H L van den Heuvel

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3 March 2020

Toon A B van Veen

2

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3 March 2020

Bing Lim

3

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3 March 2020

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23 December 2013

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3 March 2020

Journal of Molecular and Cellular Cardiology

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3 March 2020

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3 March 2020

12-25

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3 March 2020

Embryonic stem cell lines derived from human blastocysts

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Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG.

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Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach.

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Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes

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Electronic "expression" of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells

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Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs

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Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells

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Calcium handling in human embryonic stem cell-derived cardiomyocytes

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Calcium homeostasis in human induced pluripotent stem cell-derived cardiomyocytes

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Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes

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Calcium handling in embryonic stem cell-derived cardiac myocytes: of mice and men.

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Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

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Facilitated maturation of Ca2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression.

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Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions.

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A molecular and genetic outline of cardiac morphogenesis.

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Heart field: from mesoderm to heart tube

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An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart

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7 January 2021

Fgf8 is required for anterior heart field development

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Mesp1 expression is the earliest sign of cardiovascular development

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7 January 2021

Regulation of heart development and function through combinatorial interactions of transcription factors

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A role for bone morphogenetic proteins in the induction of cardiac myogenesis

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Wnt antagonism initiates cardiogenesis in Xenopus laevis

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7 January 2021

BMP signaling is required for heart formation in vertebrates

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7 January 2021

Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration

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Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart

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7 January 2021

Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development

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7 January 2021

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation

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7 January 2021

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis

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7 January 2021

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

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7 January 2021

GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development

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7 January 2021

GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm

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7 January 2021

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7 January 2021

Over-expression of GATA-6 in Xenopus embryos blocks differentiation of heart precursors

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7 January 2021

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

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7 January 2021

The Xenopus GATA-4/5/6 genes are associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis

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7 January 2021

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A positive GATA element and a negative vitamin D receptor-like element control atrial chamber-specific expression of a slow myosin heavy-chain gene during cardiac morphogenesis

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7 January 2021

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A subclass of bHLH proteins required for cardiac morphogenesis

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7 January 2021

Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development

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Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation

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A hyperpolarization activated inward current (If) is present in infant ventricular myocytes

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Developmental changes in action potential and membrane currents in fetal, neonatal and adult guinea-pig ventricular myocytes.

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Gene expression of SERCA2a and L- and T-type Ca channels during human heart development

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Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents

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7 January 2021

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Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells

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7 January 2021

Pharmacological response of human cardiomyocytes derived from virus-free induced pluripotent stem cells

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7 January 2021

Cardiomyocyte differentiation of human induced pluripotent stem cells

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7 January 2021

In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes

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7 January 2021

Global transcriptional profiling reveals similarities and differences between human stem cell-derived cardiomyocyte clusters and heart tissue

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7 January 2021

Cardiomyocyte clusters derived from human embryonic stem cells share similarities with human heart tissue

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7 January 2021

Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation

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Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes

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Human pluripotent stem cell-derived cardiomyocytes: response to TTX and lidocain reveals strong cell to cell variability

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7 January 2021

Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes

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7 January 2021

Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype

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The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells

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7 January 2021

Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes.

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7 January 2021

In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes

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7 January 2021

Isolation and characterization of I(Kr) in cardiac myocytes by Cs+ permeation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Modelling the long QT syndrome with induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Tissue engineering of vascularized cardiac muscle from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Na+/Ca2+ exchanger is a determinant of excitation-contraction coupling in human embryonic stem cell-derived ventricular cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Functional sarcoplasmic reticulum for calcium handling of human embryonic stem cell-derived cardiomyocytes: insights for driven maturation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

In vivo differentiation of induced pluripotent stem cell-derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Absence of transverse tubules contributes to non-uniform Ca(2+) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

The effect of extracellular matrix on embryonic stem cell-derived cardiomyocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Human fetal heart development after mid-term: morphometry and ultrastructural study

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Force-frequency relationship in intact mammalian ventricular myocardium: physiological and pathophysiological relevance

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Growth of engineered human myocardium with mechanical loading and vascular coculture

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

1,4,5-Inositol trisphosphate-operated intracellular Ca(2+) stores and angiotensin-II/endothelin-1 signaling pathway are functional in human embryonic stem cell-derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Handmade cloned transgenic sheep rich in omega-3 Fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Modeling myocardial growth and hypertrophy in engineered heart muscle

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Multiple promoter elements interact to control the transcription of the potassium channel gene, KCNJ2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Cardiac T-type Ca(2+) channels in the heart

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Expression of microRNAs and their target mRNAs in human stem cell-derived cardiomyocyte clusters and in heart tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell-derived ventricular cardiomyocytes: insights for driven maturation and hypertrophic growth.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Developmental changes in functional expression and beta-adrenergic regulation of I(f) in the heart of mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Tetrodotoxin-sensitive sodium current in rat fetal ventricular myocytes--contribution to the plateau phase of action potential.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Effects of endothelin-1 on calcium and potassium currents in undiseased human ventricular myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Postnatal changes in T-type calcium current density in rat atrial myocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Contribution of I Kr and I K1 to ventricular repolarization in canine and human myocytes: is there any influence of action potential duration?

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

A study of the developmental changes in outward currents of rat ventricular myocytes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.12.011

7 January 2021

Identifiers

10.1016/J.YJMCC.2013.12.011

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24370890%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24370890%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

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