(Q38177887)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24417641%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Crosstalk among p53 family members in cutaneous carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24417641%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24417641%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Dario Antonini

series ordinal

2

1 reference

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5 March 2020

publication date

1 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24417641%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

published in

Experimental Dermatology

1 reference

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5 March 2020

volume

23

1 reference

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5 March 2020

issue

3

1 reference

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5 March 2020

page(s)

143-146

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24417641%20AND%20SRC:MED&resulttype=core&format=json

Cutaneous squamous-cell carcinoma

5 March 2020

cites work

1 reference

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

21 January 2018

1 reference

Human skin cancer stem cells: a tale of mice and men.

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RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

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Temporal dissection of tumorigenesis in primary cancers

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Loss of CDKN2A and p14ARF expression occurs frequently in human nonmelanoma skin cancers.

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Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

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COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

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Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

21 January 2018

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p53 mutations in cancer

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer.

21 January 2018

1 reference

Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes

21 January 2018

1 reference

p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop

21 January 2018

1 reference

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity

21 January 2018

1 reference

p73 or p53 directly regulates human p53 transcription to maintain cell cycle checkpoints.

21 January 2018

1 reference

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

21 January 2018

1 reference

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

21 January 2018

1 reference

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

21 January 2018

1 reference

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

21 January 2018

1 reference

Direct targets of the TRP63 transcription factor revealed by a combination of gene expression profiling and reverse engineering

21 January 2018

1 reference

Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

21 January 2018

1 reference

p53 and p73 display common and distinct requirements for sequence specific binding to DNA

21 January 2018

1 reference

Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo

21 January 2018

1 reference

Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63.

21 January 2018

1 reference

ΔNp63α represses anti-proliferative genes via H2A.Z deposition.

21 January 2018

1 reference

Frequent clones of p53-mutated keratinocytes in normal human skin

21 January 2018

1 reference

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia

21 January 2018

1 reference

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations

21 January 2018

1 reference

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases

21 January 2018

1 reference

Transcriptional repression of miR-34 family contributes to p63-mediated cell cycle progression in epidermal cells

21 January 2018

1 reference

A miR-34a-SIRT6 axis in the squamous cell differentiation network

21 January 2018

1 reference

The miR-34 family in cancer and apoptosis

21 January 2018

1 reference

Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells

21 January 2018

1 reference

Infrared radiation does not enhance the frequency of ultraviolet radiation-induced skin tumors, but their growth behaviour in mice.

21 January 2018

1 reference

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

21 January 2018

1 reference

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

21 January 2018

1 reference

An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations

21 January 2018

1 reference

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

p63 regulates an adhesion programme and cell survival in epithelial cells

21 January 2018

1 reference

Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma

21 January 2018

1 reference

TAp63 induces senescence and suppresses tumorigenesis in vivo

21 January 2018

1 reference

ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis

21 January 2018

1 reference

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

21 January 2018

1 reference

p63 is the molecular switch for initiation of an epithelial stratification program

21 January 2018

1 reference

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

21 January 2018

1 reference

p63 regulates proliferation and differentiation of developmentally mature keratinocytes

21 January 2018

1 reference

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

21 January 2018

1 reference

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

21 January 2018

1 reference

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

21 January 2018

1 reference

Expansion of epidermal progenitors with high p63 phosphorylation during wound healing of mouse epidermis

21 January 2018

1 reference

Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma

21 January 2018

1 reference

AIS is an oncogene amplified in squamous cell carcinoma

21 January 2018

1 reference

High-resolution genomic profiles of human lung cancer

21 January 2018

1 reference

The mutational landscape of head and neck squamous cell carcinoma

21 January 2018

1 reference

Regulation of in situ to invasive breast carcinoma transition

21 January 2018

1 reference

Loss of p63 expression is associated with tumor progression in bladder cancer

21 January 2018

1 reference

Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis

21 January 2018

1 reference

p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.

21 January 2018

1 reference

p63 expression in normal skin and usual cutaneous carcinomas

21 January 2018

1 reference

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

21 January 2018

1 reference

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

21 January 2018

1 reference

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

21 January 2018

1 reference

Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition

21 January 2018

1 reference

Notch signaling represses p63 expression in the developing surface ectoderm

21 January 2018

1 reference

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation

21 January 2018

1 reference

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

21 January 2018

1 reference

The p53 family member genes are involved in the Notch signal pathway

21 January 2018

1 reference

Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas

21 January 2018

1 reference

IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes

21 January 2018

1 reference

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias

21 January 2018

1 reference

Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice.

21 January 2018

1 reference

Role of p53 family members p73 and p63 in human hematological malignancies

21 January 2018

1 reference

TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma.

21 January 2018

1 reference

DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

21 January 2018

1 reference

Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo

21 January 2018

1 reference

DeltaTAp73 upregulation correlates with poor prognosis in human tumors: putative in vivo network involving p73 isoforms, p53, and E2F-1.

21 January 2018

1 reference

Expression of deltaNp73 predicts poor prognosis in lung cancer

21 January 2018

1 reference

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer

21 January 2018

1 reference

Evaluation of p63 and p73 antibodies for cross-reactivity

21 January 2018

1 reference

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

21 January 2018

1 reference

Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway

21 January 2018

1 reference

p73 loss triggers conversion to squamous cell carcinoma reversible upon reconstitution with TAp73alpha.

21 January 2018

1 reference

Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling

21 January 2018

1 reference

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference