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RBR E3-ligases at work
scientific article published on 27 January 2014
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Europe PubMed Central
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3989860
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
title
RBR E3-ligases at work
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3989860
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
author
Titia Sixma
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2
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Europe PubMed Central
PMCID
3989860
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
author name string
Judith J Smit
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
3989860
reference URL
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6 March 2020
publication date
27 January 2014
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Europe PubMed Central
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3989860
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retrieved
6 March 2020
published in
EMBO Reports
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Europe PubMed Central
PMCID
3989860
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
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6 March 2020
volume
15
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Europe PubMed Central
PMCID
3989860
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6 March 2020
issue
2
1 reference
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Europe PubMed Central
PMCID
3989860
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
page(s)
142-154
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Europe PubMed Central
PMCID
3989860
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6 March 2020
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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
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6 September 2017
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
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NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase
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6 September 2017
The p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosis
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A human protein-protein interaction network: a resource for annotating the proteome
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The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells
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6 September 2017
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
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6 September 2017
Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Parkin and relatives: the RBR family of ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Oxidative modifications of alpha-synuclein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Dorfin Localizes to Lewy Bodies and Ubiquitylates Synphilin-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Parc: a cytoplasmic anchor for p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
E3 ubiquitin-protein ligase activity of Parkin is dependent on cooperative interaction of RING finger (TRIAD) elements
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
TRIADs: a new class of proteins with a novel cysteine-rich signature
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
6 September 2017
E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
Identification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
Functional modulation of parkin through physical interaction with SUMO-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
14 September 2017
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
28 September 2017
Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
23 June 2018
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
23 June 2018
Analysis of nuclear factor-κB (NF-κB) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-κB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
23 June 2018
The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
23 June 2018
Comparative genomics of the RBR family, including the Parkinson's disease-related gene parkin and the genes of the ariadne subfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
23 June 2018
Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
S-nitrosylation regulates mitochondrial quality control via activation of parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Hox-mediated regulation of doublesex sculpts sex-specific abdomen morphology in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Neddylation positively regulates the ubiquitin E3 ligase activity of parkin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Downregulation of uridine-cytidine kinase like-1 decreases proliferation and enhances tumor susceptibility to lysis by apoptotic agents and natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Understanding cell death in Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989860
retrieved
31 August 2018
Identification of molecular determinants required for interaction of ubiquitin-conjugating enzymes and RING finger proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24469331
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24469331
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Q64860635
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24469331
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEMBR.201338166
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin in the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEMBR.201338166
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/EMBR.201338166
1 reference
stated in
Europe PubMed Central
PMCID
3989860
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
PMCID
3989860
1 reference
stated in
Europe PubMed Central
PMCID
3989860
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
PubMed ID
24469331
1 reference
stated in
Europe PubMed Central
PMCID
3989860
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469331%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
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