(Q38196732)

30 August 2017

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title

Monoclonal antibodies for migraine: preventing calcitonin gene-related peptide activity (English)

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30 August 2017

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1

Marcelo E Bigal

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30 August 2017

Sarah Walter

2

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30 August 2017

publication date

1 May 2014

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30 August 2017

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30 August 2017

volume

28

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30 August 2017

issue

5

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30 August 2017

page(s)

389-399

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Alpha-CGRP and beta-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion.

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Investigation of the structure/activity relationship of human calcitonin gene-related peptide (CGRP).

21 January 2018

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Molecular pharmacology of receptors for calcitonin-gene-related peptide, amylin and adrenomedullin

21 January 2018

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Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: trigeminal origin and co-existence with substance P.

21 January 2018

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Calcitonin gene-related peptide: functional role in cerebrovascular regulation

21 January 2018

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Release of calcitonin gene-related peptide from sensory neurons

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level

21 January 2018

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Calcitonin gene-related peptide (CGRP): perivascular distribution and vasodilatory effects.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Is CGRP a marker for chronic migraine?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

CGRP and NO in the trigeminal system: mechanisms and role in headache generation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Possible sites of action of the new calcitonin gene-related peptide receptor antagonists

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

CGRP and its receptors provide new insights into migraine pathophysiology

21 January 2018

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Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine

21 January 2018

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Emerging target-based paradigms to prevent and treat migraine

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

21 January 2018

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Migraine--current understanding and treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Diencephalic and brainstem mechanisms in migraine

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Migraine in the triptan era: lessons from epidemiology, pathophysiology, and clinical science

21 January 2018

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https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

What is migraine? Controversy and stalemate in migraine pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Pathophysiology of the migraine aura. The spreading depression theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

The slow voltage variation of cortical spreading depression of activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Nitroglycerin sensitises in healthy subjects CNS structures involved in migraine pathophysiology: evidence from a study of nociceptive blink reflexes and visual evoked potentials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Brain stem activation in spontaneous human migraine attacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

A positron emission tomographic study in spontaneous migraine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Central neuromodulation in chronic migraine patients with suboccipital stimulators: a PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Brainstem activation specific to migraine headache.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Headache may arise from perturbation of brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Headache secondary to deep brain implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Neurovascular headache and a midbrain vascular malformation: evidence for a role of the brainstem in chronic migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

New onset migraine with a brain stem cavernous angioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Symptomatic migraine and pontine vascular malformation: evidence for a key role of the brainstem in the pathophysiology of chronic migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Calcitonin gene-related peptide antagonists as treatments of migraine and other primary headaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Pathophysiology of headache--past and present

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Evolution of the CT/CGRP family: comparative study with new data from models of teleosts, the eel, and cephalopod molluscs, the cuttlefish and the nautilus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Correlation between CGRP and migraine attacks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

CGRP: sensory neuropeptide with multiple neurologic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Central projection of calcitonin gene-related peptide (CGRP)- and substance P (SP)-immunoreactive trigeminal primary neurons in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Calcitonin gene-related peptide differentially regulates gene and protein expression in trigeminal glia cells: findings from array analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Immunohistochemical characterization of calcitonin gene-related peptide in the trigeminal system of the familial hemiplegic migraine 1 knock-in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Calcitonin gene-related peptide receptor expression in the neurons and glia of developing rat cerebellum: an autoradiographic and immunohistochemical analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Advances in understanding the mechanisms of migraine-type photophobia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

CGRP may play a causative role in migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Calcitonin gene-related peptide (CGRP) and migraine current understanding and state of development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: results from a phase II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Early development of therapeutic biologics--pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards subcommittee of the American Academy of Neurology and the American Headache Society

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Augmented contraction of the human isolated coronary artery by sumatriptan: a possible role for endogenous thromboxane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Pharmacology of receptors for calcitonin gene-related peptide and amylin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: Results of the Phase 1 program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Randomized, controlled trial of telcagepant for the acute treatment of migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-014-0156-4

Cardiovascular and hemodynamic parameters in women following prolonged CGRP inhibition using LBR-101, a monoclonal antibody against CGRP

21 January 2018

1 reference

12 December 2020

Comparison of the vasoconstrictor properties of the 5-HT1D-receptor agonists rizatriptan (MK-462) and sumatriptan in human isolated coronary artery: outcome of two independent studies using different experimental protocols

1 reference

12 December 2020

Clinical perspectives of calcitonin gene related peptide pharmacology.

1 reference

12 December 2020

Antagonism by some ergot derivatives of 5-HT-induced vasoconstriction

1 reference

12 December 2020

Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system

1 reference

12 December 2020

BMS-927711 for the acute treatment of migraine

1 reference

12 December 2020

Calcitonin gene-related peptide (CGRP)-immunoreactive nerve varicosities in synaptic contact with sensory neurons in the trigeminal ganglion of rats

1 reference

12 December 2020

Humanized antibodies and their applications

1 reference

12 December 2020

Neurogenic inflammation in the pathophysiology and treatment of migraine.

1 reference

12 December 2020

The development of neurogenic plasma extravasation in the rat dura mater does not depend upon the degranulation of mast cells

1 reference

12 December 2020

CGRP immunohistochemistry in wound healing and dentin bridge formation following rat molar pulpotomy

1 reference

12 December 2020

Mechanisms of action of serotonin 5-HT1B/D agonists: insights into migraine pathophysiology using rizatriptan

1 reference

12 December 2020

1 reference

12 December 2020

Differential expression of alpha-CGRP and beta-CGRP by primary sensory neurons and enteric autonomic neurons of the rat

1 reference

12 December 2020

The calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS reduces neurogenic increases in dural blood flow

1 reference

12 December 2020

Further observations on the spreading depression of activity in the cerebral cortex.

1 reference

12 December 2020

Modification of vasoconstrictor responses in cerebral blood vessels by lesioning of the trigeminal nerve: possible involvement of CGRP.

1 reference

12 December 2020

Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain

1 reference

12 December 2020

Headache caused by a single lesion of multiple sclerosis in the periaqueductal gray area

1 reference

12 December 2020

CGRP: blood flow and more?

1 reference

12 December 2020

Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms.

1 reference

12 December 2020

BMS-927711 for the acute treatment of migraine: a double-blind, randomized, placebo controlled, dose-ranging trial

1 reference

12 December 2020

Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin

1 reference

12 December 2020

Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: differences between peripheral and central CGRP receptor distrib

1 reference

12 December 2020

10.1007/S40263-014-0156-4

Identifiers

DOI

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30 August 2017

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