(Q38202991)

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Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells

scientific article published on May 2014

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scholarly article

1 reference

Europe PubMed Central

30 August 2017

Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells (English)

1 reference

Europe PubMed Central

30 August 2017

Hiromasa Morikawa

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Shimon Sakaguchi

2

object named as

Shimon Sakaguchi

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

1 May 2014

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Europe PubMed Central

30 August 2017

Immunological Reviews

1 reference

Europe PubMed Central

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13 June 2020

259

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24712467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

192-205

1 reference

Europe PubMed Central

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13 June 2020

Regulatory T cells and immune tolerance

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Regulatory T cells and Foxp3

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

An essential role for Scurfin in CD4+CD25+ T regulatory cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Epigenetic mechanisms in mammals

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Epigenetics and gene expression

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Epigenetic regulation of adipogenesis.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Epigenetic control of the foxp3 locus in regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

FOXP3 controls regulatory T cell function through cooperation with NFAT

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

A two-step process for thymic regulatory T cell development.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

DNA methylation controls Foxp3 gene expression

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Regulatory T cell development in the absence of functional Foxp3.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

CTLA-4 control over Foxp3+ regulatory T cell function

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Thymus, innate immunity and autoimmune arthritis: interplay of gene and environment

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Role of LAG-3 in regulatory T cells.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Control of T-cell activation by CD4+ CD25+ suppressor T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Transforming growth factor-beta regulation of immune responses

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

IL-35-mediated induction of a potent regulatory T cell population.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Anergic T cells as suppressor cells in vitro

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Regulatory T cells: stability revisited

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Regulatory T cell plasticity: beyond the controversies.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

FOXP3+ regulatory T cells in the human immune system

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Phenotypical and functional specialization of FOXP3+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Development and maintenance of regulatory T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Foxp3-dependent programme of regulatory T-cell differentiation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12174

21 January 2018

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