(Q38203938)

31 August 2017

title

Defining the genomic landscape of head and neck cancers through next-generation sequencing (English)

1 reference

31 August 2017

author

Anthony Charles Nichols

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

G Rizzo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

M Black

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

J S Mymryk

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

J W Barrett

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

30 April 2014

1 reference

31 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

e11-24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725020%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 June 2020

massive parallel sequencing

1 reference

based on heuristic

inferred from title

cites work

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

1 reference

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability

21 January 2018

1 reference

Genome structural variation discovery and genotyping

21 January 2018

1 reference

The interplay between HPV and host immunity in head and neck squamous cell carcinoma

21 January 2018

1 reference

Human papillomavirus and survival of patients with oropharyngeal cancer.

21 January 2018

1 reference

Phase III randomized, placebo-controlled trial of docetaxel with or without gefitinib in recurrent or metastatic head and neck cancer: an eastern cooperative oncology group trial

21 January 2018

1 reference

Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

21 January 2018

1 reference

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage

21 January 2018

1 reference

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

1 reference

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

21 January 2018

1 reference

DNA damage signals through differentially modified E2F1 molecules to induce apoptosis

21 January 2018

1 reference

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 January 2018

1 reference

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

21 January 2018

1 reference

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

21 January 2018

1 reference

Emerging roles of E2Fs in cancer: an exit from cell cycle control

21 January 2018

1 reference

The quest to overcome resistance to EGFR-targeted therapies in cancer

21 January 2018

1 reference

Comprehensive molecular characterization of clear cell renal cell carcinoma

21 January 2018

1 reference

The genetic basis for cancer treatment decisions

21 January 2018

1 reference

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule

21 January 2018

1 reference

Do all patients with head and neck cancer benefit from radiotherapy and concurrent cetuximab?

21 January 2018

1 reference

Alzheimer's failure raises questions about disease-modifying strategies

21 January 2018

1 reference

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

21 January 2018

1 reference

Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity

21 January 2018

1 reference

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

Epidermal growth factor receptor targeting in head and neck cancer: have we been just skimming the surface?

21 January 2018

1 reference

PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer

21 January 2018

1 reference

PI3K pathway inhibitors approach junction.

21 January 2018

1 reference

A complex interplay between Akt, TSC2 and the two mTOR complexes

21 January 2018

1 reference

Functional analysis of PIK3CA gene mutations in human colorectal cancer

21 January 2018

1 reference

Genomic instability of the host cell induced by the human papillomavirus replication machinery

21 January 2018

1 reference

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

21 January 2018

1 reference

Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq

21 January 2018

1 reference

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function

21 January 2018

1 reference

PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

21 January 2018

1 reference

A modified method for whole exome resequencing from minimal amounts of starting DNA

21 January 2018

1 reference

Mutational heterogeneity in cancer and the search for new cancer-associated genes

21 January 2018

1 reference

Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors

21 January 2018

1 reference

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

21 January 2018

1 reference

Lessons learned from next-generation sequencing in head and neck cancer

21 January 2018

1 reference

Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

21 January 2018

1 reference

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

21 January 2018

1 reference

Cisplatin and radiotherapy with or without erlotinib in locally advanced squamous cell carcinoma of the head and neck: a randomized phase II trial

21 January 2018

1 reference

Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines

21 January 2018

1 reference

Human papillomavirus oncoproteins: pathways to transformation

21 January 2018

1 reference

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.

21 January 2018

1 reference

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

21 January 2018

1 reference

Comprehensive molecular characterization of human colon and rectal cancer

21 January 2018

1 reference

A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing

21 January 2018

1 reference

High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer

21 January 2018

1 reference

Notch1 functions as a tumor suppressor in mouse skin

21 January 2018

1 reference

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

1 reference

PI3K-Akt pathway: its functions and alterations in human cancer

21 January 2018

1 reference

p300 acts as a transcriptional coactivator for mammalian Notch-1

21 January 2018

1 reference

Molecular changes in oral cancer may reflect aetiology and ethnic origin

21 January 2018

1 reference

Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers

21 January 2018

1 reference

Flipping the safety catch of procaspase-3.

21 January 2018

1 reference

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

21 January 2018

1 reference

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

21 January 2018

1 reference

The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci

21 January 2018

1 reference

High frequency of mutations of the PIK3CA gene in human cancers

21 January 2018

1 reference

The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival

21 January 2018

1 reference

PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity

21 January 2018

1 reference

Losses of 3p14 and 9p21 as shown by fluorescence in situ hybridization are early events in tumorigenesis of oral squamous cell carcinoma and already occur in simple keratosis

21 January 2018

1 reference

p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

21 January 2018

1 reference

Dedicated protection for the female germline

21 January 2018

1 reference

The mutational landscape of head and neck squamous cell carcinoma

21 January 2018

1 reference

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

21 January 2018

1 reference

The PI3K/Akt/mTOR axis in head and neck cancer: functions, aberrations, cross-talk, and therapies.

21 January 2018

1 reference

Platinum-based chemotherapy plus cetuximab in head and neck cancer

21 January 2018

1 reference

Recombinant adenovirus encoding H-ras ribozyme induces apoptosis in laryngeal cancer cells through caspase- and mitochondria-dependent pathways

21 January 2018

1 reference

Prognostic significance of cyclinD1 amplification and the co-alteration of cyclinD1/pRb/ppRb in patients with esophageal squamous cell carcinoma

21 January 2018

1 reference

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

21 January 2018

1 reference