(Q38205413)

31 August 2017

title

Cis-regulatory variation: significance in biomedicine and evolution (English)

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31 August 2017

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Simon Friedensohn

1

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31 August 2017

Ritwick Sawarkar

series ordinal

2

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31 August 2017

publication date

18 April 2014

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31 August 2017

published in

Cell and Tissue Research

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31 August 2017

volume

356

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31 August 2017

issue

3

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31 August 2017

page(s)

495-505

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https://scigraph.springernature.com/pub.10.1007/s00441-014-1855-3

31 August 2017

exact match

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cites work

An integrated map of genetic variation from 1,092 human genomes

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Genome-wide inference of natural selection on human transcription factor binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Genome-wide quantitative enhancer activity maps identified by STARR-seq

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Emergence and diversification of fly pigmentation through evolution of a gene regulatory module

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Exome sequencing as a tool for Mendelian disease gene discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A twin approach to unraveling epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

An integrated encyclopedia of DNA elements in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Modification of enhancer chromatin: what, how, and why?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Evolution of hsp70 gene expression: a role for changes in AT-richness within promoters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

DNase I sensitivity QTLs are a major determinant of human expression variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Common regulatory variation impacts gene expression in a cell type-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A genome-wide association study of global gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A rare variant in the osteoarthritis-associated locus GDF5 is functional and reveals a site that can be manipulated to modulate GDF5 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Meta-analysis methods for genome-wide association studies and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A second generation human haplotype map of over 3.1 million SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Homozygous deletion of an EGR2 enhancer in congenital amyelinating neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Hemophilia B Leyden and once mysterious cis-regulatory mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A map of open chromatin in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Revealing the architecture of gene regulation: the promise of eQTL studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Chromatin landscape dictates HSF binding to target DNA elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Passive and active DNA methylation and the interplay with genetic variation in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3'-UTR via altered RNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The International HapMap Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Effect of natural genetic variation on enhancer selection and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The locus of evolution: evo devo and the genetics of adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Gene expression variation in African and European populations of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Assessing the impact of transgenerational epigenetic variation on complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Using HapMap tools in pharmacogenomic discovery: the thiopurine methyltransferase polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Cooperative transcription factor associations discovered using regulatory variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Evolution of regulatory sequences in 12 Drosophila species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The pursuit of genome-wide association studies: where are we now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Epistatic selection between coding and regulatory variation in human evolution and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Adaptive evolution of multiple traits through multiple mutations at a single gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Three periods of regulatory innovation during vertebrate evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The Drosophila melanogaster Genetic Reference Panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The study of eQTL variations by RNA-seq: from SNPs to phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Bringing genome-wide association findings into clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Systematic localization of common disease-associated variation in regulatory DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Locus-specific editing of histone modifications at endogenous enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Genetic analysis of genome-wide variation in human gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Candidate gene association studies: a comprehensive guide to useful in silico tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Interpretation of developmental signaling at chromatin: the Polycomb perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Hsp90@chromatin.nucleus: an emerging hub of a networker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Hsp90 globally targets paused RNA polymerase to regulate gene expression in response to environmental stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Common genetic variants account for differences in gene expression among ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Analysis of variation at transcription factor binding sites in Drosophila and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Population differences in the rate of proliferation of international HapMap cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Exonic transcription factor binding directs codon choice and affects protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Gene-expression variation within and among human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Population genomics of human gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

The evolutionary significance of cis-regulatory mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Evaluation of genetic variation contributing to differences in gene expression between populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Cohort Profile: The Dutch Hunger Winter Families Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

Questions over the scientific basis of epigenome project

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-1855-3

10.1007/S00441-014-1855-3

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

31 August 2017

1021699389

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Fatcat ID

release_wpdmtieunzfilkoelsbo5ysp6y

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Fatcat

https://api.fatcat.wiki/v0/release/wpdmtieunzfilkoelsbo5ysp6y

mapped directly with Wikidata item

24 November 2022

based on heuristic

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