(Q38209300)

31 August 2017

title

Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease (English)

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31 August 2017

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2

Piero Ruggenenti

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31 August 2017

14

Esteban Porrini

2 references

ORCID Public Data File 2021

31 August 2017

1

Aiko P J de Vries

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31 August 2017

Xiong Z Ruan

3

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31 August 2017

Manuel Praga

4

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31 August 2017

Josep M Cruzado

5

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31 August 2017

Ingeborg M Bajema

6

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31 August 2017

Vivette D D'Agati

7

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31 August 2017

Hildo J Lamb

8

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31 August 2017

Drazenka Pongrac Barlovic

9

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31 August 2017

Radovan Hojs

10

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31 August 2017

Manuela Abbate

11

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31 August 2017

Rosa Rodriquez

12

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31 August 2017

Carl Erik Mogensen

13

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31 August 2017

ERA-EDTA Working Group Diabesity

15

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31 August 2017

publication date

1 May 2014

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The Lancet: Diabetes & Endocrinology

31 August 2017

published in

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31 August 2017

volume

2

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31 August 2017

issue

5

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31 August 2017

page(s)

417-426

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Evolving importance of kidney disease: from subspecialty to global health burden

31 August 2017

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Insulin's acute effects on glomerular filtration rate correlate with insulin sensitivity whereas insulin's acute effects on proximal tubular sodium reabsorption correlation with salt sensitivity in normal subjects.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Podocyte lesions in patients with obesity-related glomerulopathy.

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7 January 2021

Obesity-associated focal segmental glomerulosclerosis: pathological features of the lesion and relationship with cardiomegaly and hyperlipidemia

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7 January 2021

Pathological influence of obesity on renal structural changes in chronic kidney disease

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7 January 2021

Renal injury in the extremely obese patients with normal renal function.

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7 January 2021

Absence of glomerular injury or nephron loss in a normotensive rat remnant kidney model

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7 January 2021

Focal segmental glomerulosclerosis

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7 January 2021

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7 January 2021

An update on the lipid nephrotoxicity hypothesis

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7 January 2021

Lipid homeostasis, lipotoxicity and the metabolic syndrome.

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7 January 2021

"Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Adipophilin/perilipin-2 as a lipid droplet-specific marker for metabolically active cells and diseases associated with metabolic dysregulation

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Leukocyte lipid bodies - Biogenesis and functions in inflammation

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7 January 2021

Macrophage differentiation to foam cells

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Lipotoxic diseases of nonadipose tissues in obesity

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7 January 2021

Disordered lipid metabolism and the pathogenesis of insulin resistance

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients

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7 January 2021

Ectopic fat storage in heart, blood vessels and kidneys in the pathogenesis of cardiovascular diseases

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7 January 2021

Extrahepatic complications of nonalcoholic fatty liver disease

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7 January 2021

Lipid redistribution in renal dysfunction

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7 January 2021

Remarks on the Fatty Transformation of the Kidney

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7 January 2021

The mesangial cell revisited: no cell is an island

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7 January 2021

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

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7 January 2021

Human mesangial cells express inducible macrophage scavenger receptor

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7 January 2021

Apolipoproteins and lipoprotein receptors in glomeruli in human kidney diseases

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7 January 2021

Very-low-density lipoprotein-induced triglyceride accumulation in human mesangial cells is mainly mediated by lipoprotein lipase.

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7 January 2021

Inflammatory cytokines disrupt LDL-receptor feedback regulation and cause statin resistance: a comparative study in human hepatic cells and mesangial cells

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7 January 2021

IGF-1-induced lipid accumulation impairs mesangial cell migration and contractile function.

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7 January 2021

Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation

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7 January 2021

Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation

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7 January 2021

Podocyte injury damages other podocytes

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7 January 2021

Glomerular epithelial stem cells: the good, the bad, and the ugly.

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7 January 2021

Growth-dependent podocyte failure causes glomerulosclerosis

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7 January 2021

Mammalian target of rapamycin and the kidney. I. The signaling pathway

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7 January 2021

mTOR signaling in growth control and disease

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7 January 2021

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

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7 January 2021

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

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7 January 2021

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

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7 January 2021

The insulin receptor and the kidney.

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7 January 2021

Insulin signaling to the glomerular podocyte is critical for normal kidney function

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7 January 2021

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

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7 January 2021

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids

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7 January 2021

Interleukin-1β enhances the intracellular accumulation of cholesterol by up-regulating the expression of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase in podocytes

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Receptor-mediated lipoprotein uptake by human glomerular cells: comparison with skin fibroblasts and HepG2 cells

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7 January 2021

Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis

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7 January 2021

CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein

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7 January 2021

Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria

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7 January 2021

Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase

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7 January 2021

Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions

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7 January 2021

Substrate-utilization of the Human Kidney

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7 January 2021

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

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7 January 2021

Clinical significance of urinary liver-type fatty acid-binding protein in patients with diabetic nephropathy

1 reference

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7 January 2021

Fatty acids exacerbate tubulointerstitial injury in protein-overload proteinuria

1 reference

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7 January 2021

Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport

1 reference

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7 January 2021

Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications

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7 January 2021

Glucose control by the kidney: an emerging target in diabetes

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7 January 2021

Liver and kidney metabolism during prolonged starvation

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7 January 2021

Deletion of the insulin receptor in the proximal tubule promotes hyperglycemia

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7 January 2021

The nephrotic syndrome: a complication of massive obesity

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Absence of hypoalbuminemia despite massive proteinuria in focal segmental glomerulosclerosis secondary to hyperfiltration

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7 January 2021

Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Nephrectomy elicits impact of age and BMI on renal hemodynamics: lower postdonation reserve capacity in older or overweight kidney donors

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7 January 2021

Glomerular volume and renal histology in obese and non-obese living kidney donors

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7 January 2021

The GFR and GFR decline cannot be accurately estimated in type 2 diabetics

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7 January 2021

Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus

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7 January 2021

Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study

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7 January 2021

Metabolic imaging of human kidney triglyceride content: reproducibility of proton magnetic resonance spectroscopy

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Renal lipid metabolism and lipotoxicity

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Renal lipids and oxygenation in diabetic mice: noninvasive quantification with MR imaging

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https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The failing heart--an engine out of fuel

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7 January 2021

Weight loss interventions in chronic kidney disease: a systematic review and meta-analysis

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7 January 2021

ACE inhibition is renoprotective among obese patients with proteinuria

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7 January 2021

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

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7 January 2021

The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria

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7 January 2021

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism

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7 January 2021

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

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7 January 2021

10.1016/S2213-8587(14)70065-8

Identifiers

DOI

1 reference

31 August 2017

1 reference