(Q38212812)

31 August 2017

title

The role of FUS gene variants in neurodegenerative diseases (English)

1 reference

31 August 2017

1 reference

3

Joseph Jankovic

1 reference

31 August 2017

Hao Deng

1

1 reference

31 August 2017

Kai Gao

series ordinal

2

1 reference

31 August 2017

language of work or name

English

0 references

publication date

20 May 2014

1 reference

31 August 2017

published in

Nature Reviews Neurology

1 reference

31 August 2017

volume

10

1 reference

31 August 2017

issue

6

1 reference

31 August 2017

page(s)

337-348

1 reference

https://scigraph.springernature.com/pub.10.1038/nrneurol.2014.78

31 August 2017

exact match

0 references

cites work

Unfolding the role of protein misfolding in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Molecular pathways of frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A new subtype of frontotemporal lobar degeneration with FUS pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS-immunoreactive intranuclear inclusions in neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The TET family of proteins: functions and roles in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetic contribution of FUS to frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Exome sequencing identifies FUS mutations as a cause of essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Domain architectures and characterization of an RNA-binding protein, TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Male sterility and enhanced radiation sensitivity in TLS(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Involvement of the pro-oncoprotein TLS (translocated in liposarcoma) in nuclear factor-kappa B p65-mediated transcription as a coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TLS inhibits RNA polymerase III transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Large-scale proteomic analysis of the human spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

P68 RNA helicase (DDX5) alters activity of cis- and trans-acting factors of the alternative splicing of H-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS-mediated alternative splicing in the nervous system: consequences for ALS and FTLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutations in FUS cause FALS and SALS in French and French Canadian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Familial ALS with FUS P525L mutation: two Japanese sisters with multiple systems involvement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS/TLS-immunoreactive neuronal and glial cell inclusions increase with disease duration in familial amyotrophic lateral sclerosis with an R521C FUS/TLS mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS mutations in amyotrophic lateral sclerosis: clinical, pathological, neurophysiological and genetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Occurrence of basophilic inclusions and FUS-immunoreactive neuronal and glial inclusions in a case of familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

An autopsied case of sporadic adult-onset amyotrophic lateral sclerosis with FUS-positive basophilic inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS i

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Abundant FUS-immunoreactive pathology in the skin of sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The genetics and neuropathology of frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Frontotemporal dementia: clinicopathological correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fused in sarcoma (FUS): an oncogene goes awry in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Pathological features of FTLD-FUS in a Japanese population: analyses of nine cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Basophilic inclusion body disease and neuronal intermediate filament inclusion disease: a comparative clinicopathological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS pathology in basophilic inclusion body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Distinct pathological subtypes of FTLD-FUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TAR DNA-binding protein 43 in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Two Italian kindreds with familial amyotrophic lateral sclerosis due to FUS mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The occurrence of mutations inFUSin a Belgian cohort of patients with familial ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

De novo truncating FUS gene mutation as a cause of sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A Japanese ALS6 family with mutation R521C in the FUS/TLS gene: a clinical, pathological and genetic report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Frameshift and novel mutations in FUS in familial amyotrophic lateral sclerosis and ALS/dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Identification of novel FUS mutations in sporadic cases of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A de novo missense mutation of the FUS gene in a "true" sporadic ALS case

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Making connections: pathology and genetics link amyotrophic lateral sclerosis with frontotemporal lobe dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS mutations in sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A novel double mutation in FUS gene causing sporadic ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS, TARDBP, and SOD1 mutations in a Taiwanese cohort with familial ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Novel FUS deletion in a patient with juvenile amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Extensive genetics of ALS: a population-based study in Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Screening of the SOD1, FUS, TARDBP, ANG, and OPTN mutations in Korean patients with familial and sporadic ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Novel FUS mutation in patients with sporadic amyotrophic lateral sclerosis and corticobasal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Evidence for an oligogenic basis of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Sporadic juvenile amyotrophic lateral sclerosis caused by mutant FUS/TLS: possible association of mental retardation with this mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

De novo FUS gene mutations are associated with juvenile-onset sporadic amyotrophic lateral sclerosis in China.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutations in the 3' untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS and TDP43 genetic variability in FTD and CBS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetics of essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Essential tremor--a neurodegenerative disorder associated with cognitive defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Identification of FUS p.R377W in essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Identification of a novel risk variant in the FUS gene in essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetic analysis of the fused in sarcoma gene in Chinese Han patients with essential tremor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS in familial essential tremor - the search for common causes is still on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Investigating the role of FUS exonic variants in essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fused in Sarcoma (FUS) gene mutations are not a frequent cause of essential tremor in Europeans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetic analysis of the FUS/TLS gene in essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetic analysis of the fused in sarcoma gene in Chinese Han patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Revisiting the relationship between essential tremor and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Neuronal gene expression correlates of Parkinson's disease with dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FET proteins in frontotemporal dementia and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A yeast functional screen predicts new candidate ALS disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS-SMN protein interactions link the motor neuron diseases ALS and SMA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Protein aggregation in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Stress granules as crucibles of ALS pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Prion-like disorders: blurring the divide between transmissibility and infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

RNA-binding proteins with prion-like domains in ALS and FTLD-U.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The seeds of neurodegeneration: prion-like spreading in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

A yeast model of FUS/TLS-dependent cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

RNA seeds higher-order assembly of FUS protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

RNA targets of wild-type and mutant FET family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Expression of human FUS protein in Drosophila leads to progressive neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Genetic heterogeneity in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

SOD1, ANG, TARDBP and FUS mutations in amyotrophic lateral sclerosis: A United States clinical testing lab experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Advances in understanding the molecular basis of frontotemporal dementia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

ANC: High quality, fast publication, open access

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Mutations of FUS gene in sporadic amyotrophic lateral sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Novel missense and truncating mutations in FUS/TLS in familial ALS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

C-terminal FUS/TLS mutations in familial and sporadic ALS in Germany

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS/TLS gene mutations are the second most frequent cause of familial ALS in the Spanish population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Lower motor neuron disease caused by a novel FUS/TLS gene frameshift mutation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Contribution of major amyotrophic lateral sclerosis genes to the etiology of sporadic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

FUS mutations in sporadic amyotrophic lateral sclerosis: Clinical and genetic analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Screening of the FUS gene in familial and sporadic amyotrophic lateral sclerosis patients of Chinese origin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TDP-43 and FUS: a nuclear affair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

Prion-like mechanisms in neurodegenerative diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

The genetics of Tourette syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2014.78

TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling

31 March 2020

1 reference

12 December 2020

FUS mutations in frontotemporal lobar degeneration with amyotrophic lateral sclerosis

1 reference

12 December 2020

Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein

1 reference

12 December 2020

hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEUROL.2014.78

1 reference

Dimensions Publication ID

31 August 2017

1036331463

0 references

1 reference