(Q38214063)

31 August 2017

title

The emerging roles of DOT1L in leukemia and normal development (English)

1 reference

31 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ino D Karemaker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Fred van Leeuwen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

C M McLean

1

1 reference

31 August 2017

I D Karemaker

2

1 reference

31 August 2017

F van Leeuwen

3

1 reference

31 August 2017

publication date

23 May 2014

1 reference

31 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

2131-2138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24854991%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/leu.2014.169

4 June 2020

exact match

0 references

cites work

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

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12 December 2020

Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates.

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12 December 2020

DOT1L regulates dystrophin expression and is critical for cardiac function

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12 December 2020

Aldosterone-sensitive repression of ENaCalpha transcription by a histone H3 lysine-79 methyltransferase

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12 December 2020

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

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12 December 2020

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

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12 December 2020

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.

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12 December 2020

Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase

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12 December 2020

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

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12 December 2020

Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis

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12 December 2020

The Tudor protein survival motor neuron (SMN) is a chromatin-binding protein that interacts with methylated lysine 79 of histone H3.

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12 December 2020

Epigenetic histone modification and cardiovascular lineage programming in mouse embryonic stem cells exposed to laminar shear stress

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12 December 2020

Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase

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12 December 2020

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.

1 reference

12 December 2020

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis

1 reference

12 December 2020

Establishment in culture of pluripotential cells from mouse embryos

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12 December 2020

Changes in H3K79 methylation during preimplantation development in mice

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De novo mutations in histone-modifying genes in congenital heart disease.

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12 December 2020

vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

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12 December 2020

Leukemic transformation

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12 December 2020

Induced pluripotency and oncogenic transformation are related processes

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12 December 2020

Essential role of DOT1L in maintaining normal adult hematopoiesis.

1 reference

12 December 2020

The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle

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12 December 2020

Human histone H3K79 methyltransferase DOT1L protein [corrected] binds actively transcribing RNA polymerase II to regulate gene expression

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12 December 2020

Overexpression of grappa encoding a histone methyltransferase enhances stress resistance in Drosophila.

1 reference

12 December 2020

Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation

1 reference

12 December 2020

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

1 reference

12 December 2020

Involvement of DOT1L in the remodeling of heterochromatin configuration during early preimplantation development in mice.

1 reference

12 December 2020

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.

1 reference

12 December 2020

The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription

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12 December 2020

Histone methylation: a dynamic mark in health, disease and inheritance

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12 December 2020

Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae

1 reference

12 December 2020

The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure

1 reference

12 December 2020

Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation

1 reference

12 December 2020

Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L

1 reference

12 December 2020

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

1 reference

12 December 2020

Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes

1 reference

12 December 2020

hDOT1L links histone methylation to leukemogenesis

1 reference

12 December 2020

lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs.

1 reference

12 December 2020

ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L.

1 reference

12 December 2020

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells

1 reference

12 December 2020

Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells

1 reference

12 December 2020

Spinal muscular atrophy: a deficiency in a ubiquitous protein; a motor neuron-specific disease

1 reference

12 December 2020

Chromatin-modifying enzymes as modulators of reprogramming

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12 December 2020

Histone H3K79 methyltransferase Dot1L is directly activated by thyroid hormone receptor during Xenopus metamorphosis

1 reference

12 December 2020

Perceptions of epigenetics

1 reference

12 December 2020

The diverse functions of Dot1 and H3K79 methylation.

1 reference

12 December 2020

Dot1p modulates silencing in yeast by methylation of the nucleosome core

1 reference

12 December 2020

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure

1 reference

12 December 2020

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)

1 reference

12 December 2020

An operational definition of epigenetics

1 reference

12 December 2020

Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development

1 reference

12 December 2020

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

12 December 2020

Exploiting the balance between life and death: targeted cancer therapy and "oncogenic shock".

1 reference

12 December 2020

Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79.

1 reference

12 December 2020

Early mammalian erythropoiesis requires the Dot1L methyltransferase

1 reference

12 December 2020

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

1 reference

12 December 2020

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

1 reference

12 December 2020

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes

1 reference

12 December 2020

Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine

1 reference

12 December 2020

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

1 reference

12 December 2020

DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions

1 reference

12 December 2020

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

1 reference

12 December 2020

Clathrin-dependent endocytosis

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2014.169

7 January 2021

inferred from DOI database lookup

Amphibian metamorphosis: An exquisite model for hormonal regulation of postembryonic development in vertebrates

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2014.169

7 January 2021