(Q42713766)

5 November 2017

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors (English)

1 reference

Erratum: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

5 November 2017

corrigendum / erratum

1 reference

12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1038/NCOMMS2845

Peter J Brown

25

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Alexander J Federation

Alexander Federation

6

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John R. Engen

John R Engen

13

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John Dick

John E Dick

23

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Cheryl Arrowsmith

Cheryl H Arrowsmith

26

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Dalia Barsyte-Lovejoy

9

Dalia Barsyte-Lovejoy

1 reference

5 November 2017

4

Wolfram Tempel

1 reference

5 November 2017

Emma J Chory

2

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Taraneh Hajian

21

Taraneh Hajian

1 reference

5 November 2017

16

Erno Wienholds

1 reference

5 November 2017

Wenyu Yu

1

1 reference

5 November 2017

Amy K Wernimont

3

1 reference

5 November 2017

Alex Scopton

5

1 reference

5 November 2017

Jason J Marineau

7

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5 November 2017

Jun Qi

8

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5 November 2017

Joanna Yi

10

1 reference

5 November 2017

Richard Marcellus

11

1 reference

5 November 2017

Roxana E Iacob

12

1 reference

5 November 2017

Carly Griffin

14

1 reference

5 November 2017

Ahmed Aman

15

1 reference

5 November 2017

Fengling Li

17

1 reference

5 November 2017

Javier Pineda

18

1 reference

5 November 2017

Guillermina Estiu

19

1 reference

5 November 2017

Tatiana Shatseva

20

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5 November 2017

Rima Al-Awar

22

1 reference

5 November 2017

Masoud Vedadi

24

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5 November 2017

James E Bradner

27

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5 November 2017

Matthieu Schapira

28

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5 November 2017

language of work or name

English

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publication date

1 January 2012

1 reference

5 November 2017

Nature Communications

1 reference

5 November 2017

3

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5 November 2017

1288

1 reference

https://scigraph.springernature.com/pub.10.1038/ncomms2304

5 November 2017

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cites work

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

1 reference

12 December 2020

Assessment of the repeatability and reproducibility of hydrogen/deuterium exchange mass spectrometry measurements.

1 reference

12 December 2020

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

1 reference

12 December 2020

The art of the chemical probe

1 reference

12 December 2020

Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies

1 reference

12 December 2020

Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells.

1 reference

12 December 2020

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

1 reference

12 December 2020

Epigenetic protein families: a new frontier for drug discovery

1 reference

12 December 2020

Protein methyltransferases as a target class for drug discovery

1 reference

12 December 2020

Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

1 reference

12 December 2020

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

1 reference

12 December 2020

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells

1 reference

12 December 2020

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis

1 reference

12 December 2020

Chromatin-modifying enzymes as modulators of reprogramming

1 reference

12 December 2020

The diverse functions of Dot1 and H3K79 methylation.

1 reference

12 December 2020

Conformational adaptation in drug-target interactions and residence time

1 reference

12 December 2020

Hydrogen exchange mass spectrometry for the analysis of protein dynamics

1 reference

12 December 2020

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)

1 reference

12 December 2020

The pathogenesis of mixed-lineage leukemia

1 reference

12 December 2020

Structural chemistry of the histone methyltransferases cofactor binding site.

1 reference

12 December 2020

Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains

1 reference

12 December 2020

MLL translocations, histone modifications and leukaemia stem-cell development

1 reference

12 December 2020

Modeling the initiation and progression of human acute leukemia in mice

1 reference

12 December 2020

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

1 reference

12 December 2020

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

1 reference

12 December 2020

Structural Chemistry of Human SET Domain Protein Methyltransferases

1 reference

12 December 2020

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

1 reference

12 December 2020

Chemogenetic analysis of human protein methyltransferases

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS2304

1 reference

Dimensions Publication ID

5 November 2017

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0 references

1 reference