(Q27674356)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

B.V.Venkataram Prasad

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Yuan Yao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Pinhong Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Jiasheng Diao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Lisheng Deng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Justin L Anglin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Yongcheng Song

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

4 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American Chemical Society

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

133

1 reference

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13 February 2020

issue

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

16746-16749

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

Chemogenetic analysis of human protein methyltransferases

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Chromatin modifications and their function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

hDOT1L links histone methylation to leukemogenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

The epigenomics of cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

MLL translocations, histone modifications and leukaemia stem-cell development

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Epigenetic regulation in psychiatric disorders

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Many paths to methyltransfer: a chronicle of convergence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Protein methyltransferases as a target class for drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Epigenetic control of T-helper-cell differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Chemical probes for histone-modifying enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Covalent modifications of histones during development and disease pathogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Analysis of prognostic factors of acute lymphoblastic leukemia in infants: report on CCG 1953 from the Children's Oncology Group

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Structural and sequence motifs of protein (histone) methylation enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Neplanocin A. A potent inhibitor of S-adenosylhomocysteine hydrolase and of vaccinia virus multiplication in mouse L929 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

S-Adenosylmethionine metabolism in HL-60 cells: effect of cell cycle and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492951

Design, synthesis, and preliminary biological evaluation of a DNA methyltransferase-directed alkylating agent

2 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21936531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21936531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA206312B

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21936531%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21936531

2 references