(Q38214324)

31 August 2017

The role of inflammation in cancer of the esophagus (English)

1 reference

31 August 2017

6

1 reference

31 August 2017

James J Phelan

2

0 references

Joanne Lysaght

object named as

Joanne Lysaght

4

0 references

Jacintha O'Sullivan

object named as

Jacintha N O'Sullivan

5

0 references

author name string

Katie E O'Sullivan

1

1 reference

PubMed ID

24857183

31 August 2017

Ciara O'Hanlon

3

1 reference

31 August 2017

23 May 2014

1 reference

Expert Review of Gastroenterology & Hepatology

31 August 2017

1 reference

31 August 2017

8

1 reference

31 August 2017

7

1 reference

31 August 2017

749-760

1 reference

Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age.

31 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Central adiposity and risk of Barrett's esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Defining a positive circumferential resection margin in oesophageal cancer and its implications for adjuvant treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Acid reflux and oesophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammation, microenvironment, and the immune system in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammation and cancer: back to Virchow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Tumors and inflammatory infiltrates: friends or foes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammation and Barrett's carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammation and esophageal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Evaluation of Helicobacter pylori in reflux oesophagitis and Barrett's oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Effects of bile acids and hydrogen ion on the fine structure of oesophageal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Toxic bile acids in gastro-oesophageal reflux disease: influence of gastric acidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Impact of the biliary diversion procedure on carcinogenesis in Barrett's esophagus surgically induced by duodenoesophageal reflux in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

21 January 2018

Inflammation and cancer

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Circulating inflammatory cytokines and adipokines are associated with increased risk of Barrett's esophagus: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Elevated tumour interleukin-1beta is associated with systemic inflammation: A marker of reduced survival in gastro-oesophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Central adiposity is associated with increased risk of esophageal inflammation, metaplasia, and adenocarcinoma: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The effects of obesity on oesophageal function, acid exposure and the symptoms of gastro-oesophageal reflux disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Is obesity an inflammatory condition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Chronic inflammation in obesity and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

What aspects of body fat are particularly hazardous and how do we measure them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Depot-specific hormonal characteristics of subcutaneous and visceral adipose tissue and their relation to the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Insulin resistance--mechanisms, syndromes, and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Leptin and gastro-intestinal malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Barrett esophagus: prevalence of central adiposity, metabolic syndrome, and a proinflammatory state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammatory gradient in Barrett's oesophagus: implications for disease complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Increased expression and secretion of interleukin-6 in patients with Barrett's esophagus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Connection between inflammation and carcinogenesis in gastrointestinal tract: focus on TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Non-Smad signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Impaired transforming growth factor beta signalling in Barrett's carcinogenesis due to frequent SMAD4 inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Dendritic cells in Barrett's esophagus carcinogenesis: an inadequate microenvironment for antitumor immunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

SPARC: a Ca2+-binding extracellular protein associated with endothelial cell injury and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

MMP-1 is a (pre-)invasive factor in Barrett-associated esophageal adenocarcinomas and is associated with positive lymph node status

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

STATs in cancer inflammation and immunity: a leading role for STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Barrett's esophagus: cancer and molecular biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Immunohistochemical study of nuclear factor-kappaB activity and interleukin-8 abundance in oesophageal adenocarcinoma; a useful strategy for monitoring these biomarkers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Mitochondrial free radical generation, oxidative stress, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The esophagitis to adenocarcinoma sequence; the role of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

In benign Barrett's epithelial cells, acid exposure generates reactive oxygen species that cause DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Glutathione and glutathione S-transferases in Barrett's epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Oxidative stress has a role in malignant transformation in Barrett's oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Reactive oxygen species: a breath of life or death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Nitric oxide-mediated invasion in Barrett's high-grade dysplasia and adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

HIF-1alpha protein expression is associated with the environmental inflammatory reaction in Barrett's metaplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Deletion at fragile sites is a common and early event in Barrett's esophagus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Chromosomal instability in Barrett's esophagus is related to telomere shortening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Q-FISH analysis of telomere and chromosome instability in the oesophagus with and without squamous cell carcinoma in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Genomic instability in patients with Barrett's esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammation-mediated genomic instability: roles of activation-induced cytidine deaminase in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett's oesophageal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The genomic landscape of oesophagogastric junctional adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Role of endothelial cell metabolism in vessel sprouting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

TNFα and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Metabolic signatures of esophageal cancer: NMR-based metabolomics and UHPLC-based focused metabolomics of blood serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Interleukin 6 enhances glycolysis through expression of the glycolytic enzymes hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

MicroRNA signatures in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

microRNAs as oncogenes and tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Inflammatory and microRNA gene expression as prognostic classifier of Barrett's-associated esophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

MicroRNA prognostic signature for nodal metastases and survival in esophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Role of aspirin in chemoprevention of esophageal adenocarcinoma: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

The role of cyclic AMP and oxygen intermediates in the inhibition of cellular immunity in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Improving surveillance for Barrett's oesophagus: AspECT and BOSS trials provide an evidence base

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Do proton pump inhibitors protect against cancer progression in GERD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Gastric acid suppression and risk of oesophageal and gastric adenocarcinoma: a nested case control study in the UK

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Esophagogastric cancer after bariatric surgery: systematic review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Statins and aspirin for chemoprevention in Barrett's esophagus: results of a cost-effectiveness analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: a nested case-control analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Modulating effect of amount and types of dietary fat on ornithine decarboxylase, tyrosine protein kinase and prostaglandins production during colon carcinogenesis in male F344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Enteral nutrition enriched with eicosapentaenoic acid (EPA) preserves lean body mass following esophageal cancer surgery: results of a double-blinded randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Molecular mechanisms of chemopreventive phytochemicals against gastroenterological cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Oxidative stress is more important than acid in the pathogenesis of reflux oesophagitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Dietary antioxidants and risk of Barrett's esophagus and adenocarcinoma of the esophagus in an Australian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Adipose tissue as an endocrine organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Visceral obesity, metabolic syndrome, insulin resistance and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Aberrant p53 protein expression is associated with an increased risk of neoplastic progression in patients with Barrett's oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Proton Pump Inhibitors Reduce the Risk of Neoplastic Progression in Patients With Barrett's Esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Nonsteroidal Anti-Inflammatory Drugs and Statins Have Chemopreventative Effects in Patients With Barrett's Esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

Time trends incidence of both major histologic types of esophageal carcinomas in selected countries, 1973-1995

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F17474124.2014.913478

10.1586/17474124.2014.913478

21 January 2018

Identifiers

DOI

1 reference

31 August 2017

1 reference

PubMed ID

24857183