(Q38237221)

31 August 2017

title

Trends in discovery of new drugs for tuberculosis therapy (English)

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31 August 2017

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Maria Rosalia Pasca

2

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Giovanna Riccardi

object named as

Giovanna Riccardi

series ordinal

1

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publication date

6 August 2014

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The Journal of Antibiotics

31 August 2017

published in

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31 August 2017

volume

67

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31 August 2017

issue

9

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31 August 2017

page(s)

655-659

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Epidemiology: A mortal foe.

31 August 2017

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Ribosomal protein S1 influences trans-translation in vitro and in vivo

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Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid

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The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol.

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Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis

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History of the Development of Rifampin

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The RNA polymerase "switch region" is a target for inhibitors

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New approaches to target the mycolic acid biosynthesis pathway for the development of tuberculosis therapeutics

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A review of tuberculosis: Focus on bedaquiline

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Selectivity of TMC207 towards mycobacterial ATP synthase compared with that towards the eukaryotic homologue

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Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis.

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PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release

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The mechanism of action of PA-824: Novel insights from transcriptional profiling

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Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patients

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An update on the use of rifapentine for tuberculosis therapy

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Safety and pharmacokinetics of escalating daily doses of the antituberculosis drug rifapentine in healthy volunteers

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SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis

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The Mycobacterium tuberculosis secreted protein Rv0203 transfers heme to membrane proteins MmpL3 and MmpL11.

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21 January 2018

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MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212

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Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.

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Indoleamides are active against drug-resistant Mycobacterium tuberculosis

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Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.

21 January 2018

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Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors

21 January 2018

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Vaccine development for tuberculosis: current progress

21 January 2018

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Global tuberculosis control: lessons learnt and future prospects

21 January 2018

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7 January 2021

Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2014.109

7 January 2021

Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2014.109

7 January 2021

Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2014.109

7 January 2021

Approaches to the development of new antituberculosis drugs

1 reference

https://api.crossref.org/works/10.1038%2FJA.2014.109

7 January 2021

Identifiers

DOI

10.1038/JA.2014.109

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Dimensions Publication ID

31 August 2017

1025924297

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1 reference