(Q37506524)

20 August 2017

1 reference

title

Mycobacterium tuberculosis: drug resistance and future perspectives (English)

1 reference

Mycobacterium tuberculosis

20 August 2017

main subject

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Silvia Buroni

3

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Maria Rosalia Pasca

object named as

Maria Rosalia Pasca

series ordinal

2

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Giovanna Riccardi

object named as

Giovanna Riccardi

series ordinal

1

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publication date

1 June 2009

1 reference

20 August 2017

number of pages

18

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based on heuristic

inferred from page(s)

published in

Future Microbiology

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20 August 2017

volume

4

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20 August 2017

issue

5

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20 August 2017

page(s)

597-614

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Host innate immune response to Mycobacterium tuberculosis

20 August 2017

cites work

1 reference

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21 January 2018

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Who puts the tubercle in tuberculosis?

21 January 2018

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The role of the granuloma in expansion and dissemination of early tuberculous infection

21 January 2018

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Host-pathogen interactions in latent Mycobacterium tuberculosis infection: identification of new targets for tuberculosis intervention

21 January 2018

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HIV-associated tuberculosis: diagnostic and treatment challenges

21 January 2018

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Key issues in multidrug-resistant tuberculosis

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The evolution of extensively drug resistant tuberculosis (XDR-TB): history, status and issues for global control

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Multidrug-resistant and extensively drug-resistant tuberculosis: a review

21 January 2018

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Extensively drug-resistant tuberculosis: current challenges and threats

21 January 2018

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Global incidence of multidrug-resistant tuberculosis

21 January 2018

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Extensively drug-resistant tuberculosis

21 January 2018

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Extensively drug-resistant tuberculosis

21 January 2018

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Molecular confirmation of bacillus Calmette-Guérin as the cause of pulmonary infection following urinary tract instillation

21 January 2018

1 reference

Prevalence of and molecular basis for tuberculosis drug resistance in the Republic of Georgia: validation of a QIAplex system for detection of drug resistance-related mutations

21 January 2018

1 reference

Simultaneous amplification and identification of 25 human papillomavirus types with Templex technology

21 January 2018

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Predominance of Mycobacterium tuberculosis EAI and Beijing lineages in Yangon, Myanmar

21 January 2018

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Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosis

21 January 2018

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The resumption of consumption -- a review on tuberculosis

21 January 2018

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Tuberculosis: evolution in millennia and minutes

21 January 2018

1 reference

Tuberculosis: drug resistance, fitness, and strategies for global control

21 January 2018

1 reference

Role of mycobacterial efflux transporters in drug resistance: an unresolved question

21 January 2018

1 reference

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

21 January 2018

1 reference

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

21 January 2018

1 reference

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

21 January 2018

1 reference

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

21 January 2018

1 reference

The mechanism of isoniazid killing: clarity through the scope of genetics

21 January 2018

1 reference

Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

21 January 2018

1 reference

Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid

21 January 2018

1 reference

Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms.

21 January 2018

1 reference

The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.

21 January 2018

1 reference

Novel mutations in ndh in isoniazid-resistant Mycobacterium tuberculosis isolates

21 January 2018

1 reference

Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.

21 January 2018

1 reference

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

21 January 2018

1 reference

Mechanism of thioamide drug action against tuberculosis and leprosy

21 January 2018

1 reference

ethA, inhA, and katG loci of ethionamide-resistant clinical Mycobacterium tuberculosis isolates

21 January 2018

1 reference

Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

21 January 2018

1 reference

Structure-based design of a novel class of potent inhibitors of InhA, the enoyl acyl carrier protein reductase from Mycobacterium tuberculosis: a computer modelling approach

21 January 2018

1 reference

A synthetic mammalian gene circuit reveals antituberculosis compounds

21 January 2018

1 reference

EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator

21 January 2018

1 reference

EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets

21 January 2018

1 reference

Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis

21 January 2018

1 reference

Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis

21 January 2018

1 reference

Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy

21 January 2018

1 reference

The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol.

21 January 2018

1 reference

Transfer of embB codon 306 mutations into clinical Mycobacterium tuberculosis strains alters susceptibility to ethambutol, isoniazid, and rifampin

21 January 2018

1 reference

Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis

21 January 2018

1 reference

Identification of differentially expressed mRNA in prokaryotic organisms by customized amplification libraries (DECAL): the effect of isoniazid on gene expression in Mycobacterium tuberculosis

21 January 2018

1 reference

Convergent evolutionary analysis identifies significant mutations in drug resistance targets of Mycobacterium tuberculosis.

21 January 2018

1 reference

Characterization of the alanine racemases from two mycobacteria

21 January 2018

1 reference

Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis

21 January 2018

1 reference

Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine

21 January 2018

1 reference

The magic bullets and tuberculosis drug targets.

21 January 2018

1 reference

Structural mechanism for rifampicin inhibition of bacterial rna polymerase

21 January 2018

1 reference

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis

21 January 2018

1 reference

Mycobacterium tuberculosis isolate with a distinct genomic identity overexpresses a tap-like efflux pump

21 January 2018

1 reference

Assessment of efflux pump gene expression in a clinical isolate Mycobacterium tuberculosis by real-time reverse transcription PCR.

21 January 2018

1 reference

Fluoroquinolones for the treatment of pulmonary tuberculosis

21 January 2018

1 reference

Fluoroquinolones, tuberculosis, and resistance

21 January 2018

1 reference

Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations

21 January 2018

1 reference

Mutagenesis in the alpha3alpha4 GyrA helix and in the Toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones

21 January 2018

1 reference

Streptomycin resistance in mycobacteria

21 January 2018

1 reference

Modulation of 16S rRNA function by ribosomal protein S12.

21 January 2018

1 reference

Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria

21 January 2018

1 reference

Identification of mutations related to streptomycin resistance in clinical isolates of Mycobacterium tuberculosis and possible involvement of efflux mechanism

21 January 2018

1 reference

Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis

21 January 2018

1 reference

First linezolid-resistant clinical isolates of Mycobacterium tuberculosis

21 January 2018

1 reference

In vitro-selected linezolid-resistant Mycobacterium tuberculosis mutants

21 January 2018

1 reference

Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli

21 January 2018

1 reference

Pyrazinamide resistance and pncA gene mutations in Mycobacterium tuberculosis

21 January 2018

1 reference

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

21 January 2018

1 reference

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

21 January 2018

1 reference

Current strategies for identifying and validating targets for new treatment-shortening drugs for TB.

21 January 2018

1 reference

High throughput crystallography of TB drug targets.

21 January 2018

1 reference

Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs

21 January 2018

1 reference

Genes required for mycobacterial growth defined by high density mutagenesis

21 January 2018

1 reference

Genetic requirements for mycobacterial survival during infection

21 January 2018

1 reference

Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis

21 January 2018

1 reference

Drug targets in mycobacterial sulfur metabolism

21 January 2018

1 reference

The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?

21 January 2018

1 reference

Attack on the scourge of tuberculosis: patented drug targets

21 January 2018

1 reference

Emerging drugs for active tuberculosis

21 January 2018

1 reference

New anti-tuberculosis drugs with novel mechanisms of action.

21 January 2018

1 reference

Moxifloxacin versus ethambutol in the first 2 months of treatment for pulmonary tuberculosis

21 January 2018

1 reference

Diarylquinolines target subunit c of mycobacterial ATP synthase

21 January 2018

1 reference

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

21 January 2018

1 reference

Current status of some antituberculosis drugs and the development of new antituberculous agents with special reference to their in vitro and in vivo antimicrobial activities

21 January 2018

1 reference

Selectivity of TMC207 towards mycobacterial ATP synthase compared with that towards the eukaryotic homologue

21 January 2018

1 reference

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

21 January 2018

1 reference

PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release

21 January 2018

1 reference

Mycobacterium leprae is naturally resistant to PA-824

21 January 2018

1 reference

Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis

21 January 2018

1 reference

Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models

21 January 2018

1 reference

Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis

21 January 2018

1 reference

OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice

21 January 2018

1 reference

BM 212 and its derivatives as a new class of antimycobacterial active agents

21 January 2018

1 reference

New derivatives of BM212: A class of antimycobacterial compounds based on the pyrrole ring as a scaffold

21 January 2018

1 reference

Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines

21 January 2018

1 reference

Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro

21 January 2018

1 reference

Extensively drug-resistant tuberculosis

21 January 2018

1 reference

A roadmap for drug discovery and its translation to small molecule agents in clinical development for tuberculosis treatment

21 January 2018

1 reference

21 January 2018

1 reference

Mechanism of Streptomycin Action on Bacteria: A Unitary Hypothesis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FMB.09.20

1 reference

20 August 2017

1 reference