(Q33995482)

30 July 2017

Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid (English)

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Mycobacterium tuberculosis

30 July 2017

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Argyrides Argyrou

1

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ORCID Public Data File 2021

author name string

Matthew W Vetting

series ordinal

2

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30 July 2017

Bola Aladegbami

series ordinal

3

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30 July 2017

John S Blanchard

series ordinal

4

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30 July 2017

30 April 2006

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Nature Structural & Molecular Biology

30 July 2017

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30 July 2017

13

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30 July 2017

408-413

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30 July 2017

5

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https://scigraph.springernature.com/pub.10.1038/nsmb1089

30 July 2017

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cites work

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The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

31 March 2020

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A fast and efficient metal-mediated oxidation of isoniazid and identification of isoniazid-NAD(H) adducts

31 March 2020

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Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

31 March 2020

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THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

31 March 2020

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Mycolic acids: structure, biosynthesis and physiological functions

31 March 2020

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Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis

31 March 2020

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Action mechanism of antitubercular isoniazid. Activation by Mycobacterium tuberculosis KatG, isolation, and characterization of inha inhibitor

31 March 2020

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The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance

31 March 2020

1 reference

Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates.

31 March 2020

1 reference

In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid

31 March 2020

1 reference

Selective Inhibition of Nucleic Acid Synthesis in Mycobacterium tuberculosis by Isoniazid

31 March 2020

1 reference

Stretching exercises--flexibility in dihydrofolate reductase catalysis

31 March 2020

1 reference

Structure, dynamics, and catalytic function of dihydrofolate reductase

31 March 2020

1 reference

Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase

31 March 2020

1 reference

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

31 March 2020

1 reference

The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization.

31 March 2020

1 reference

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

31 March 2020

1 reference

Identification of differentially expressed mRNA in prokaryotic organisms by customized amplification libraries (DECAL): the effect of isoniazid on gene expression in Mycobacterium tuberculosis

31 March 2020

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Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization

31 March 2020

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Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis

31 March 2020

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The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action.

31 March 2020

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The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.

31 March 2020

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Quantitative proteomic analysis of drug-induced changes in mycobacteria

31 March 2020

1 reference

Spontaneous Formation of the Bioactive Form of the Tuberculosis Drug Isoniazid

31 March 2020

1 reference

Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis

31 March 2020

1 reference

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

31 March 2020

1 reference

Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resistance

31 March 2020

1 reference

Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis

31 March 2020

1 reference

Kinetic mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli.

31 March 2020

1 reference

The CCP4 suite: programs for protein crystallography

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB1089

1 reference

Dimensions Publication ID

30 July 2017

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