(Q38239454)

31 August 2017

title

Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis (English)

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31 August 2017

Marina V Rodnina

3

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Wolfgang Wintermeyer

series ordinal

2

object named as

Wolfgang Wintermeyer

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31 August 2017

1

Wolf Holtkamp

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31 August 2017

language of work or name

English

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publication date

13 August 2014

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31 August 2017

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31 August 2017

volume

36

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31 August 2017

issue

10

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31 August 2017

page(s)

908-918

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Catalysis of ribosomal translocation by sparsomycin

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Factor-free ("non-enzymic") and factor-dependent systems of translation of polyuridylic acid by Escherichia coli ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Spontaneous reverse movement of mRNA-bound tRNA through the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Reverse translocation of tRNA in the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Intermediate states in the movement of transfer RNA in the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

tRNA dynamics on the ribosome during translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

A ratchet-like inter-subunit reorganization of the ribosome during translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Following movement of the L1 stalk between three functional states in single ribosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Identification of two distinct hybrid state intermediates on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The role of L1 stalk-tRNA interaction in the ribosome elongation cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Conformation and dynamics of ribosomal stalk protein L12 in solution and on the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structures of the bacterial ribosome at 3.5 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structure of ratcheted ribosomes with tRNAs in hybrid states

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Spontaneous formation of the unlocked state of the ribosome is a multistep process

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structures of the ribosome in intermediate states of ratcheting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structural characterization of mRNA-tRNA translocation intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Intersubunit movement is required for ribosomal translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

EF-G-catalyzed translocation of anticodon stem-loop analogs of transfer RNA in the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Destabilization of the P site codon-anticodon helix results from movement of tRNA into the P/E hybrid state within the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Role of hybrid tRNA-binding states in ribosomal translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Energetic contribution of tRNA hybrid state formation to translocation catalysis on the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

EF-G-independent reactivity of a pre-translocation-state ribosome complex with the aminoacyl tRNA substrate puromycin supports an intermediate (hybrid) state of tRNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Peptidyl-tRNA regulates the GTPase activity of translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Locking and unlocking of ribosomal motions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Coordinated conformational and compositional dynamics drive ribosome translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Single-molecule fluorescence measurements of ribosomal translocation dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The hybrid state of tRNA binding is an authentic translation elongation intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Transfer RNA-mediated regulation of ribosome dynamics during protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Spontaneous intersubunit rotation in single ribosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Fluctuations of transfer RNAs between classical and hybrid states

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Energy barriers and driving forces in tRNA translocation through the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Kinetically competent intermediates in the translocation step of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Control of Ribosomal Subunit Rotation by Elongation Factor G

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Elongation factor G bound to the ribosome in an intermediate state of translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Elongation factor G stabilizes the hybrid-state conformation of the 70S ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structure of the ribosome with elongation factor G trapped in the pretranslocation state

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The antibiotic viomycin traps the ribosome in an intermediate state of translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

mRNA translocation occurs during the second step of ribosomal intersubunit rotation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Rotation of the head of the 30S ribosomal subunit during mRNA translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Dual use of GTP hydrolysis by elongation factor G on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Following translation by single ribosomes one codon at a time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The "allosteric three-site model" of elongation cannot be confirmed in a well-defined ribosome system from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Real-time tRNA transit on single translating ribosomes at codon resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structural basis for hygromycin B inhibition of protein biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Distinct functions of elongation factor G in ribosome recycling and translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Crystal structure of a mutant elongation factor G trapped with a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Essential role of histidine 84 in elongation factor Tu for the chemical step of GTP hydrolysis on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Control of phosphate release from elongation factor G by ribosomal protein L7/12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The guanine nucleotide-binding switch in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The role of guanosine 5′-triphosphate in polypeptide chain elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Elongation factor Tu, a GTPase triggered by codon recognition on the ribosome: mechanism and GTP consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Noninvasive measurement of the mechanical force generated by motor protein EF-G during ribosome translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Messenger RNA interactions in the decoding center control the rate of translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Contribution of intersubunit bridges to the energy barrier of ribosomal translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Programmed -1 frameshifting by kinetic partitioning during impeded translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

Mapping the ribosomal RNA neighborhood of protein L11 by directed hydroxyl radical probing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400076

21 January 2018

Identifiers

DOI

10.1002/BIES.201400076

1 reference

31 August 2017

1 reference