(Q38239632)

31 August 2017

title

PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011 - 2014). (English)

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31 August 2017

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Akhilesh Kumar Tamrakar

series ordinal

1

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31 August 2017

Chandan K Maurya

series ordinal

2

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31 August 2017

Amit K Rai

series ordinal

3

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31 August 2017

language of work or name

English

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publication date

14 August 2014

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Expert Opinion on Therapeutic Patents

31 August 2017

published in

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31 August 2017

volume

24

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31 August 2017

issue

10

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31 August 2017

page(s)

1101-1115

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Global and societal implications of the diabetes epidemic

31 August 2017

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cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family

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Activation of a Phosphotyrosine Phosphatase by Tyrosine Phosphorylation

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A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen

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PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity

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Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

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Mechanism of protein tyrosine phosphatase 1B-mediated inhibition of leptin signalling

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

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Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

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Neuronal PTP1B regulates body weight, adiposity and leptin action.

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Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle

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Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

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New oral therapies for type 2 diabetes mellitus: The glitazones or insulin sensitizers

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Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats

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Prodrugs of phosphates and phosphonates

21 January 2018

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Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding

21 January 2018

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The role of vanadium in the management of diabetes

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Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics

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Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents

21 January 2018

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Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agent

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pharmacological inhibition of protein tyrosine phosphatase 1B: a promising strategy for the treatment of obesity and type 2 diabetes mellitus

21 January 2018

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The evolving role of natural products in drug discovery

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Effects of berberine on glucose metabolism in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Insulin sensitizing and insulinotropic action of berberine from Cortidis rhizoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Berberine inhibits PTP1B activity and mimics insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Docking simulations and in vitro assay unveil potent inhibitory action of papaverine against protein tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Cinnamic acid, from the bark of Cinnamomum cassia, regulates glucose transport via activation of GLUT4 on L6 myotubes in a phosphatidylinositol 3‐kinase‐independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Natural PTP1B inhibitors from Broussonetia papyrifera

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Inhibitory effect of chalcones and their derivatives from Glycyrrhiza inflata on protein tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Genistein-derivatives from Tetracera scandens stimulate glucose-uptake in L6 myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Identification of pongamol and karanjin as lead compounds with antihyperglycemic activity from Pongamia pinnata fruits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Natural products possessing protein tyrosine phosphatase 1B (PTP1B) inhibitory activity found in the last decades

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Cembrane diterpenoids from the soft coral Sarcophyton trocheliophorum Marenzeller as a new class of PTP1B inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Unprecedented Diterpenoids as a PTP1B Inhibitor from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Triterpenoids and a sterol from the stem-bark of Styrax japonica and their protein tyrosine phosphatase 1B inhibitory activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Structural characterization and bioactivity evaluation of an acidic proteoglycan extract from Ganoderma lucidum fruiting bodies for PTP1B inhibition and anti-diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Protein tyrosine phosphatase 1B (PTP1B) inhibitors from Morinda citrifolia (Noni) and their insulin mimetic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

PTP1B and TCPTP--nonredundant phosphatases in insulin signaling and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B by insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

QSAR Studies of PTP1B Inhibitors: Recent Advances and Perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2014.947268

10.1517/13543776.2014.947268

21 January 2018

Identifiers

DOI

1 reference

31 August 2017

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