(Q38243219)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Bacterial surface appendages as targets for novel antibacterial therapeutics (English)

1 reference

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13 March 2020

4

1 reference

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13 March 2020

author name string

David Steadman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Alvin Lo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Gabriel Waksman

series ordinal

3

1 reference

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13 March 2020

publication date

1 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

number of pages

14

1 reference

based on heuristic

inferred from page(s)

published in

Future Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

887-900

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25156378%20AND%20SRC:MED&resulttype=core&format=json

Surface organelles assembled by secretion systems of Gram-negative bacteria: diversity in structure and function

13 March 2020

cites work

1 reference

Chemical attenuation of pilus function and assembly in Gram-negative bacteria

21 January 2018

1 reference

Urinary tract infections: disease panorama and challenges

21 January 2018

1 reference

Curli biogenesis and function

21 January 2018

1 reference

Targeting the type III secretion system to treat bacterial infections.

21 January 2018

1 reference

Identification of the binding site of Brucella VirB8 interaction inhibitors

21 January 2018

1 reference

Targeting virulence: a new paradigm for antimicrobial therapy

21 January 2018

1 reference

Fighting bacterial infections-future treatment options

21 January 2018

1 reference

Pilus biogenesis at the outer membrane of Gram-negative bacterial pathogens.

21 January 2018

1 reference

Chaperone-usher pathways: diversity and pilus assembly mechanism

21 January 2018

1 reference

The molecular dissection of the chaperone-usher pathway

21 January 2018

1 reference

Structural biology of the chaperone-usher pathway of pilus biogenesis

21 January 2018

1 reference

Intracellular bacterial biofilm-like pods in urinary tract infections.

21 January 2018

1 reference

The Gal(alpha 1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract.

21 January 2018

1 reference

FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria

21 January 2018

1 reference

Structural and energetic basis of folded-protein transport by the FimD usher

21 January 2018

1 reference

Structural basis of chaperone function and pilus biogenesis

21 January 2018

1 reference

P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips

21 January 2018

1 reference

Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli

21 January 2018

1 reference

Biogenesis of E. coli Pap pili: papH, a minor pilin subunit involved in cell anchoring and length modulation

21 January 2018

1 reference

FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae

21 January 2018

1 reference

Pilus chaperones represent a new type of protein-folding catalyst.

21 January 2018

1 reference

Catalysis of protein folding by chaperones in pathogenic bacteria

21 January 2018

1 reference

X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli

21 January 2018

1 reference

Chaperone-Subunit-Usher Interactions Required for Donor Strand Exchange during Bacterial Pilus Assembly

21 January 2018

1 reference

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism

21 January 2018

1 reference

Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation

21 January 2018

1 reference

Mechanism of fibre assembly through the chaperone-usher pathway

21 January 2018

1 reference

Molecular mechanism of P pilus termination in uropathogenic Escherichia coli

21 January 2018

1 reference

Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection

21 January 2018

1 reference

Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex

21 January 2018

1 reference

Antiadhesion therapy for urinary tract infections--a balanced PK/PD profile proved to be key for success

21 January 2018

1 reference

FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation.

21 January 2018

1 reference

Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists

21 January 2018

1 reference

The tyrosine gate as a potential entropic lever in the receptor-binding site of the bacterial adhesin FimH

21 January 2018

1 reference

Structure-Based Drug Design and Optimization of Mannoside Bacterial FimH Antagonists

21 January 2018

1 reference

Treatment and prevention of urinary tract infection with orally active FimH inhibitors

21 January 2018

1 reference

Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice.

21 January 2018

1 reference

A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131.

21 January 2018

1 reference

Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

21 January 2018

1 reference

Targeting the bacteria-host interface: strategies in anti-adhesion therapy

21 January 2018

1 reference

Adhesive organelles of Gram-negative pathogens assembled with the classical chaperone/usher machinery: structure and function from a clinical standpoint

21 January 2018

1 reference

Thiazolylaminomannosides as potent antiadhesives of type 1 piliated Escherichia coli isolated from Crohn's disease patients

21 January 2018

1 reference

Quantitative studies of the binding of the class II PapG adhesin from uropathogenic Escherichia coli to oligosaccharides

21 January 2018

1 reference

Discovery of potent inhibitors of PapG adhesins from uropathogenic Escherichia coli through synthesis and evaluation of galabiose derivatives

21 January 2018

1 reference

Inhibition of P-fimbriated Escherichia coli adhesion by multivalent galabiose derivatives studied by a live-bacteria application of surface plasmon resonance.

21 January 2018

1 reference

Snapshots of usher-mediated protein secretion and ordered pilus assembly

21 January 2018

1 reference

Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization

21 January 2018

1 reference

Design and parallel solid-phase synthesis of ring-fused 2-pyridinones that target pilus biogenesis in pathogenic bacteria

21 January 2018

1 reference

Stereoselective synthesis of optically active bicyclic beta-lactam carboxylic acids that target pilus biogenesis in pathogenic bacteria

21 January 2018

1 reference

Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins

21 January 2018

1 reference

C-Terminal properties are important for ring-fused 2-pyridones that interfere with the chaperone function in uropathogenic E. coli.

21 January 2018

1 reference

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria.

21 January 2018

1 reference

Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity

21 January 2018

1 reference

Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity

21 January 2018

1 reference

Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure-activity study

21 January 2018

1 reference

Design and synthesis of fluorescent pilicides and curlicides: bioactive tools to study bacterial virulence mechanisms

21 January 2018

1 reference

Diversity, biogenesis and function of microbial amyloids

21 January 2018

1 reference

The C-terminal repeating units of CsgB direct bacterial functional amyloid nucleation

21 January 2018

1 reference

CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation

21 January 2018

1 reference

Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF

21 January 2018

1 reference

Controlling polymerization of beta-amyloid and prion-derived peptides with synthetic small molecule ligands.

21 January 2018

1 reference

Modulation of curli assembly and pellicle biofilm formation by chemical and protein chaperones

21 January 2018

1 reference

Therapeutic approaches to Alzheimer's disease.

21 January 2018

1 reference

Microwave-assisted decarboxylation of bicyclic 2-pyridone scaffolds and identification of Abeta-peptide aggregation inhibitors

21 January 2018

1 reference

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

21 January 2018

1 reference

Structural overview of the bacterial injectisome

21 January 2018

1 reference

Biogenesis, regulation, and targeting of the type III secretion system

21 January 2018

1 reference

Role of SycD, the chaperone of the Yersinia Yop translocators YopB and YopD.

21 January 2018

1 reference

The type III secretion injectisome

21 January 2018

1 reference

Small molecules aimed at type III secretion systems to inhibit bacterial virulence

21 January 2018

1 reference

Chemical inhibitors of the type three secretion system: disarming bacterial pathogens

21 January 2018

1 reference

Discovery and characterization of inhibitors of Pseudomonas aeruginosa type III secretion

21 January 2018

1 reference

N-hydroxybenzimidazole inhibitors of the transcription factor LcrF in Yersinia: novel antivirulence agents

21 January 2018

1 reference

Characterization of the effects of salicylidene acylhydrazide compounds on type III secretion in Escherichia coli O157:H7.

21 January 2018

1 reference

Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1.

21 January 2018

1 reference

A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis

21 January 2018

1 reference

Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium

21 January 2018

1 reference

Small-molecule type III secretion system inhibitors block assembly of the Shigella type III secreton

21 January 2018

1 reference

An inhibitor of gram-negative bacterial virulence protein secretion

21 January 2018

1 reference

Substituted 2-imino-5-arylidenethiazolidin-4-one inhibitors of bacterial type III secretion.

21 January 2018

1 reference

Tethered thiazolidinone dimers as inhibitors of the bacterial type III secretion system.

21 January 2018

1 reference

Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis

21 January 2018

1 reference

Targeting type III secretion in Yersinia pestis

21 January 2018

1 reference

A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.

21 January 2018

1 reference

Guadinomines, Type III secretion system inhibitors, produced by Streptomyces sp. K01-0509. I: taxonomy, fermentation, isolation and biological properties

21 January 2018

1 reference

Identification of small-molecule inhibitors of Yersinia pestis Type III secretion system YscN ATPase.

21 January 2018

1 reference

Mechanisms of, and barriers to, horizontal gene transfer between bacteria

21 January 2018

1 reference

Role of type IV secretion in Helicobacter pylori pathogenesis

21 January 2018

1 reference

Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions

21 January 2018

1 reference

Structure of a type IV secretion system core complex.

21 January 2018

1 reference

Structure of the outer membrane complex of a type IV secretion system

21 January 2018

1 reference

Structure of a type IV secretion system

21 January 2018

1 reference

Energetic components VirD4, VirB11 and VirB4 mediate early DNA transfer reactions required for bacterial type IV secretion.

21 January 2018

1 reference

The VirB5 protein localizes to the T-pilus tips in Agrobacterium tumefaciens

21 January 2018

1 reference

Agrobacterium tumefaciens type IV secretion protein VirB3 is an inner membrane protein and requires VirB4, VirB7, and VirB8 for stabilization

21 January 2018

1 reference

Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity

21 January 2018

1 reference

An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation.

21 January 2018

1 reference

Dissecting the Machinery That Introduces Disulfide Bonds in Pseudomonas aeruginosa

21 January 2018

1 reference

DSB proteins and bacterial pathogenicity.

21 January 2018

1 reference