(Q38246755)

1 September 2017

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title

Recent advances on cellular therapies and immune modulators for graft-versus-host disease (English)

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1 September 2017

Perla Filippini

1

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Sergio Rutella

object named as

Sergio Rutella

series ordinal

2

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publication date

8 September 2014

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Expert Review of Clinical Immunology

1 September 2017

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1 September 2017

10

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1 September 2017

10

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1 September 2017

1357-1374

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Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant

1 September 2017

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

"Designed" grafts for HLA-haploidentical stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Adoptive immunotherapy with antigen-specific T cells during extracorporeal membrane oxygenation (ECMO) for adenovirus-related respiratory failure in a child given haploidentical stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Emerging concepts in haematopoietic cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Advances in graft-versus-host disease biology and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Advances in predicting acute GVHD

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4(+) T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Prevention of acute graft-versus-host disease by humanized anti-CD26 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

IFNγR signaling mediates alloreactive T-cell trafficking and GVHD

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Prior rituximab correlates with less acute graft-versus-host disease and better survival in B-cell lymphoma patients who received allogeneic peripheral blood stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Rituximab for steroid-refractory chronic graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Tolerogenic dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Nomenclature of monocytes and dendritic cells in blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Dendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Tolerogenic dendritic cells: cytokine modulation comes of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Vasoactive intestinal peptide induces regulatory dendritic cells that prevent acute graft-versus-host disease while maintaining the graft-versus-tumor response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Vasoactive intestinal peptide generates human tolerogenic dendritic cells that induce CD4 and CD8 regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Immunization with host-type CD8{alpha}+ dendritic cells reduces experimental acute GVHD in an IL-10-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Regulatory T-cell compartmentalization and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Association of Foxp3 regulatory gene expression with graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Numbers of Foxp3-expressing CD4+CD25high T cells do not correlate with the establishment of long-term tolerance after allogeneic stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Clinical perspectives for regulatory T cells in transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Tolerance, not immunity, crucially depends on IL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Interleukin-2 and regulatory T cells in graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Th2 cell therapy of established acute graft-versus-host disease requires IL-4 and IL-10 and is abrogated by IL-2 or host-type antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Mesenchymal stromal cells: sensors and switchers of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Stromal cells-are they really useful for GVHD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Bone marrow mesenchymal stromal cells to treat tissue damage in allogeneic stem cell transplant recipients: correlation of biological markers with clinical responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Alterations in the cellular immune compartment of patients treated with third-party mesenchymal stromal cells following allogeneic hematopoietic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Granulocyte colony-stimulating factor promotes the generation of regulatory DC through induction of IL-10 and IFN-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Biologic and molecular effects of granulocyte colony-stimulating factor in healthy individuals: recent findings and current challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Granulocyte colony-stimulating factor: a novel mediator of T cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Induction of natural killer T cell-dependent alloreactivity by administration of granulocyte colony-stimulating factor after bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

G-CSF given after haematopoietic stem cell transplantation using HLA-identical sibling donors is associated to a higher incidence of acute GVHD II-IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Stem cell mobilization with G-CSF analogs: a rational approach to separate GVHD and GVL?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Postgrafting administration of granulocyte colony-stimulating factor impairs functional immune recovery in recipients of human leukocyte antigen haplotype-mismatched hematopoietic transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Granulocyte and granulocyte-macrophage colony-stimulating factors in allografts: uses, misuses, misconceptions, and future applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Impact of posttransplantation G-CSF on outcomes of allogeneic hematopoietic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Hepatocyte growth factor preserves graft-versus-leukemia effect and T-cell reconstitution after marrow transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Inducible apoptosis as a safety switch for adoptive cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Extracorporeal photopheresis for paediatric patients experiencing graft-versus-host disease (GVHD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Maturation state of dendritic cells during the extracorporeal photopheresis and its relevance for the treatment of chronic graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Regulatory T cells and extracorporeal photochemotherapy: correlation with clinical response and decreased frequency of proinflammatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Extracorporeal photochemotherapy induces arginase 1 in patients with graft versus host disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Indoleamine 2,3-dioxygenase and tumor-induced tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Tryptophan catabolism is associated with acute GVHD after human allogeneic stem cell transplantation and indicates activation of indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Selectively T cell-depleted allografts from HLA-matched sibling donors followed by low-dose posttransplantation immunosuppression to improve transplantation outcome in patients with hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Immune reconstitution in recipients of photodepleted HLA-identical sibling donor stem cell transplantations: T cell subset frequencies predict outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Role for granulocyte colony-stimulating factor in the generation of human T regulatory type 1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Ultra-low dose interleukin-2 promotes immune-modulating function of regulatory T cells and natural killer cells in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Immune cell subset counts associated with graft-versus-host disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Donor Treatment with a Multipegylated G-CSF Maximizes Graft-versus-Leukemia Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Donor pretreatment with progenipoietin-1 is superior to granulocyte colony-stimulating factor in preventing graft-versus-host disease after allogeneic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

G-CSF MODULATES CYTOKINE PROFILE OF DENDRITIC CELLS AND DECREASES ACUTE GRAFT-VERSUS-HOST DISEASE THROUGH EFFECTS ON THE DONOR RATHER THAN THE RECIPIENT

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

Unique Abnormalities of CD4+ and CD8+ Central Memory Cells Associated with Chronic Graft-versus-Host Disease Improve after Extracorporeal Photopheresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2014.955475

10.1586/1744666X.2014.955475

21 January 2018

Identifiers

DOI

1 reference

1 September 2017

1 reference

PubMed ID

25196777