(Q38256642)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

1 reference

title

Metabolomic-based strategies for anti-parasite drug discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Michael P. Barrett

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Michael P Barrett

series ordinal

2

1 reference

1 September 2017

publication date

3 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

44-55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25281738%20AND%20SRC:MED&resulttype=core&format=json

Global mass spectrometry based metabolomics profiling of erythrocytes infected with Plasmodium falciparum

20 February 2020

cites work

1 reference

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Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei

21 January 2018

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Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum

21 January 2018

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Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation

21 January 2018

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LeishCyc: a guide to building a metabolic pathway database and visualization of metabolomic data

21 January 2018

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Central carbon metabolism of Leishmania parasites

21 January 2018

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Discovery of gene function by expression profiling of the malaria parasite life cycle

21 January 2018

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Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania

21 January 2018

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Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei

21 January 2018

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Management of trypanosomiasis and leishmaniasis

21 January 2018

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Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology.

21 January 2018

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Thousands of chemical starting points for antimalarial lead identification

21 January 2018

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Global phenotypic screening for antimalarials

21 January 2018

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Development and optimization of a novel 384-well anti-malarial imaging assay validated for high-throughput screening

21 January 2018

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Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

21 January 2018

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Drug repositioning in the treatment of malaria and TB.

21 January 2018

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Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei.

21 January 2018

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Growth, drug susceptibility, and gene expression profiling of Plasmodium falciparum cultured in medium supplemented with human serum or lipid-rich bovine serum albumin [corrected].

21 January 2018

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Extraction of hydrophilic metabolites from Plasmodium falciparum-infected erythrocytes for metabolomic analysis

21 January 2018

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Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism

21 January 2018

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Sample size and replication in 2D gel electrophoresis studies

21 January 2018

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Inhibition of the glycolytic enzymes in the trypanosome: an approach in the development of new leads in the therapy of parasitic diseases

21 January 2018

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Fast sampling for quantitative microbial metabolomics

21 January 2018

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Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites.

21 January 2018

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Benznidazole biotransformation and multiple targets in Trypanosoma cruzi revealed by metabolomics

21 January 2018

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Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

CE-ESI-MS metabolic fingerprinting of Leishmania resistance to antimony treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

A molecular mechanism for eflornithine resistance in African trypanosomes

21 January 2018

1 reference

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Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines

21 January 2018

1 reference

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Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses.

21 January 2018

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Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

21 January 2018

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A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057114551519

Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis

21 January 2018

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Toward global metabolomics analysis with hydrophilic interaction liquid chromatography-mass spectrometry: improved metabolite identification by retention time prediction

21 January 2018

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Recent developments in liquid-phase separation techniques for metabolomics

21 January 2018

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Proposed minimum reporting standards for chemical analysis

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057114551519

XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis

21 January 2018

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MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data

21 January 2018

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MetAlign: interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing

21 January 2018

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MathDAMP: a package for differential analysis of metabolite profiles

21 January 2018

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GMD@CSB.DB: the Golm Metabolome Database

21 January 2018

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FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry

21 January 2018

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IDEOM: an Excel interface for analysis of LC-MS-based metabolomics data

21 January 2018

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HMDB: the Human Metabolome Database

21 January 2018

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Featured organism: Danio rerio, the zebrafish

21 January 2018

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Identification of "known unknowns" utilizing accurate mass data and ChemSpider

21 January 2018

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METLIN: a metabolite mass spectral database

21 January 2018

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Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentation

21 January 2018

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Automatic chemical structure annotation of an LC-MS(n) based metabolic profile from green tea.

21 January 2018

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MetFusion: integration of compound identification strategies

21 January 2018

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Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database

21 January 2018

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Automated pipeline for de novo metabolite identification using mass-spectrometry-based metabolomics

21 January 2018

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An untargeted metabolomic workflow to improve structural characterization of metabolites

21 January 2018

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Molecular tools for the rapid detection of drug resistance in animal trypanosomes.

21 January 2018

1 reference

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21 January 2018

American trypanosomiasis

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Drug resistance in leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Reduction of pentavalent antimony by trypanothione and formation of a binary and ternary complex of antimony(III) and trypanothione.

21 January 2018

1 reference

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Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes.

21 January 2018

1 reference

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Multi-analytical platform metabolomic approach to study miltefosine mechanism of action and resistance in Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Antimalarial drug resistance and combination chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Parallel evolution of adaptive mutations in Plasmodium falciparum mitochondrial DNA during atovaquone-proguanil treatment

21 January 2018

1 reference

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Atovaquone resistance in malaria parasites

21 January 2018

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Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum

21 January 2018

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Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum

21 January 2018

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Malarial parasites and antioxidant nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Plasmodium falciparum is dependent on de novo myo-inositol biosynthesis for assembly of GPI glycolipids and infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Glutathione transport: a new role for PfCRT in chloroquine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Fitness of drug-resistant malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Quantitative metabolome analysis using liquid chromatography-high-resolution mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Metabolite identification: are you sure? And how do your peers gauge your confidence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114551519