(Q38258834)

1 September 2017

1 reference

title

Mycobacterium tuberculosis evolutionary pathogenesis and its putative impact on drug development (English)

1 reference

Mycobacterium tuberculosis

1 September 2017

0 references

0 references

author

Alessandro Cascioferro

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Jean-Louis Herrmann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Roland Brosch

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Fabien Le Chevalier

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Laleh Majlessi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

1 reference

1 January 2014

1 reference

1 September 2017

number of pages

17

1 reference

based on heuristic

inferred from page(s)

published in

Future Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

969-985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus

5 June 2020

cites work

1 reference

Whole-genome sequencing to identify transmission of Mycobacterium abscessus between patients with cystic fibrosis: a retrospective cohort study

21 January 2018

1 reference

Increased virulence of an epidemic strain of Mycobacterium massiliense in mice

21 January 2018

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Mycobacterium abscessus: a new antibiotic nightmare

21 January 2018

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Inhaled therapies, azithromycin and Mycobacterium abscessus in cystic fibrosis patients

21 January 2018

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Acquisition of clarithromycin resistance mutations in the 23S rRNA gene of Mycobacterium abscessus in the presence of inducible erm(41).

21 January 2018

1 reference

Massive gene decay in the leprosy bacillus

21 January 2018

1 reference

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

21 January 2018

1 reference

Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants

21 January 2018

1 reference

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

21 January 2018

1 reference

Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis

21 January 2018

1 reference

Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state

21 January 2018

1 reference

Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure.

21 January 2018

1 reference

Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

21 January 2018

1 reference

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins

21 January 2018

1 reference

Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis

21 January 2018

1 reference

Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus

21 January 2018

1 reference

Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

21 January 2018

1 reference

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

21 January 2018

1 reference

Vitamin B(12) metabolism in Mycobacterium tuberculosis

21 January 2018

1 reference

The population dynamics and control of tuberculosis

21 January 2018

1 reference

Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis

21 January 2018

1 reference

Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

21 January 2018

1 reference

Genes required for mycobacterial growth defined by high density mutagenesis

21 January 2018

1 reference

Genetic requirements for mycobacterial survival during infection

21 January 2018

1 reference

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism

21 January 2018

1 reference

The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth

21 January 2018

1 reference

Pristinamycin-inducible gene regulation in mycobacteria.

21 January 2018

1 reference

Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents

21 January 2018

1 reference

Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis

21 January 2018

1 reference

Emergence and spread of extensively and totally drug-resistant tuberculosis, South Africa

21 January 2018

1 reference

Advances in the development of new tuberculosis drugs and treatment regimens

21 January 2018

1 reference

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

21 January 2018

1 reference

The diarylquinoline TMC207 for multidrug-resistant tuberculosis

21 January 2018

1 reference

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

21 January 2018

1 reference

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

21 January 2018

1 reference

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.

21 January 2018

1 reference

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

21 January 2018

1 reference

SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis

21 January 2018

1 reference

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

21 January 2018

1 reference

The mechanism of action of PA-824: Novel insights from transcriptional profiling

21 January 2018

1 reference

Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis

21 January 2018

1 reference

A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms

21 January 2018

1 reference

New drugs for the treatment of tuberculosis: hope and reality

21 January 2018

1 reference

Linezolid for treatment of chronic extensively drug-resistant tuberculosis

21 January 2018

1 reference

Sterilizing activities of novel combinations lacking first- and second-line drugs in a murine model of tuberculosis

21 January 2018

1 reference

Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA

21 January 2018

1 reference

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

21 January 2018

1 reference

Synthetic EthR inhibitors boost antituberculous activity of ethionamide

21 January 2018

1 reference

Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis

21 January 2018

1 reference

Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis

21 January 2018

1 reference

Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis

21 January 2018

1 reference

Systematic genetic nomenclature for type VII secretion systems.

21 January 2018

1 reference

ESX/type VII secretion systems and their role in host-pathogen interaction

21 January 2018

1 reference

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

21 January 2018

1 reference

Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: essentiality and rescue by iron and zinc

21 January 2018

1 reference

The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability

21 January 2018

1 reference

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

21 January 2018

1 reference

Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential

21 January 2018

1 reference

21 January 2018

1 reference

Protein export by the mycobacterial SecA2 system is determined by the preprotein mature domain

21 January 2018

1 reference

The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases

21 January 2018

1 reference

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

21 January 2018

1 reference

Protein export systems of Mycobacterium tuberculosis: novel targets for drug development?

21 January 2018

1 reference

The Tat protein export pathway

21 January 2018

1 reference

Identification of functional Tat signal sequences in Mycobacterium tuberculosis proteins

21 January 2018

1 reference

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis

21 January 2018

1 reference

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

21 January 2018

1 reference

Conditionally replicating mycobacteriophages: a system for transposon delivery to Mycobacterium tuberculosis

21 January 2018

1 reference

Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis

21 January 2018

1 reference

Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice

21 January 2018

1 reference

SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis

21 January 2018

1 reference

Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans.

21 January 2018

1 reference

Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis

21 January 2018

1 reference

Interferon-gamma release assays for tuberculosis: current and future applications

21 January 2018

1 reference

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

21 January 2018

1 reference

The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

21 January 2018

1 reference

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

21 January 2018

1 reference

Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis.

21 January 2018

1 reference

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

21 January 2018

1 reference

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

21 January 2018

1 reference

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

21 January 2018

1 reference

ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells

21 January 2018

1 reference

Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

21 January 2018

1 reference

Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis

21 January 2018

1 reference

The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis

21 January 2018

1 reference

Targeting type VII/ESX secretion systems for development of novel antimycobacterial drugs

21 January 2018

1 reference

Mutually dependent secretion of proteins required for mycobacterial virulence.

21 January 2018

1 reference

A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

21 January 2018

1 reference

Secreted transcription factor controls Mycobacterium tuberculosis virulence

21 January 2018

1 reference

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

21 January 2018

1 reference

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

21 January 2018

1 reference

MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response.

21 January 2018

1 reference

An essential role for phoP in Mycobacterium tuberculosis virulence

21 January 2018

1 reference

The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis

21 January 2018

1 reference

Long-range transcriptional control of an operon necessary for virulence-critical ESX-1 secretion in Mycobacterium tuberculosis

21 January 2018

1 reference

Composition of the type VII secretion system membrane complex.

21 January 2018

1 reference

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

21 January 2018

1 reference

Immunotherapy markedly increases the effectiveness of antimicrobial therapy for treatment of Burkholderia pseudomallei infection

21 January 2018

1 reference

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

21 January 2018

1 reference

Whole genome sequencing versus traditional genotyping for investigation of a Mycobacterium tuberculosis outbreak: a longitudinal molecular epidemiological study

21 January 2018

1 reference

Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

21 January 2018

1 reference

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

21 January 2018

1 reference

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FMB.14.70

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25302954%20AND%20SRC:MED&resulttype=core&format=json

release_zgdtkto3xvbitirc3uwqsnbvwq

5 June 2020

Fatcat ID

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24 November 2022

based on heuristic

1 reference

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