(Q38260767)

1 September 2017

Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation (English)

1 reference

1 September 2017

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Juan E Tichauer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Betsi Flores

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Bernardita Soler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Laura Eugenín-von Bernhardi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Gigliola Ramírez

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

publication date

29 December 2013

1 reference

Brain, Behavior, and Immunity

1 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

187-196

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3951654/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms.

1 reference

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Microglia demonstrate age-dependent interaction with amyloid-β fibrils

6 September 2017

1 reference

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Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge

6 September 2017

1 reference

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Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders

6 September 2017

1 reference

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Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

6 September 2017

1 reference

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Glial cell dysregulation: a new perspective on Alzheimer disease

6 September 2017

1 reference

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TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

6 September 2017

1 reference

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Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase

6 September 2017

1 reference

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TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

6 September 2017

1 reference

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Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

6 September 2017

1 reference

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SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

6 September 2017

1 reference

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Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

6 September 2017

1 reference

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Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

6 September 2017

1 reference

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Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy

6 September 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

6 September 2017

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

6 September 2017

1 reference

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TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3.

6 September 2017

1 reference

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Expression of scavenger receptors in glial cells. Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound beta-amyloid

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Modulation of interferon-γ-induced glial cell activation by transforming growth factor β1: a role for STAT1 and MAPK pathways.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Reduction of beta-amyloid-induced neurotoxicity on hippocampal cell cultures by moderate acidosis is mediated by transforming growth factor beta.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

NGF promotes microglial migration through the activation of its high affinity receptor: modulation by TGF-beta.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Transforming growth factor-β stimulates β amyloid uptake by microglia through Smad3-dependent mechanisms.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Proinflammatory stimuli are needed for induction of microglial cell-mediated AbetaPP_{244-C} and Abeta-neurotoxicity in hippocampal cultures.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Altered subcellular location of phosphorylated Smads in Alzheimer's disease.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients.

31 August 2018

1 reference

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Pro- and anti-inflammatory cytokines regulate the ERK pathway: implication of the timing for the activation of microglial cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Protection of rat primary hippocampal cultures from A beta cytotoxicity by pro-inflammatory molecules is mediated by astrocytes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Transforming growth factor-beta 1 produced by hippocampal cells modulates microglial reactivity in culture.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951654

Transforming growth factor β1 modulates amyloid β-induced glial activation through the Smad3-dependent induction of MAPK phosphatase-1

31 August 2018

1 reference

12 December 2020

Increased cerebrospinal fluid levels of transforming growth factor-beta1 in Alzheimer's disease

1 reference

12 December 2020

Modulation by astrocytes of microglial cell-mediated neuroinflammation: effect on the activation of microglial signaling pathways

1 reference

12 December 2020

Proliferating culture of aged microglia for the study of neurodegenerative diseases

1 reference

12 December 2020

TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment

1 reference

12 December 2020

10.1016/J.BBI.2013.12.018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24380849%20AND%20SRC:MED&resulttype=core&format=json