(Q48369527)

11 February 2018

title

Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice. (English)

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11 February 2018

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Sylvain Lesné

1

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Fabian Docagne

Fabian Docagne

2

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Géraldine Liot

Géraldine Liot

4

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Luc Buée

Luc Buée

6

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Eric T MacKenzie

9

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11 February 2018

Alain Buisson

Alain Buisson

10

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Denis Vivien

Denis Vivien

11

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author name string

Cecilia Gabriel

3

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11 February 2018

Debomoy K Lahiri

5

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11 February 2018

Laurent Plawinski

7

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11 February 2018

André Delacourte

8

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11 February 2018

language of work or name

English

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publication date

7 March 2003

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11 February 2018

Journal of Biological Chemistry

number of pages

11

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based on heuristic

inferred from page(s)

published in

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11 February 2018

volume

278

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11 February 2018

issue

20

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11 February 2018

page(s)

18408-18418

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11 February 2018

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

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Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

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Elevated circulating tumor necrosis factor levels in Alzheimer's disease

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Altered expression of transforming growth factor-beta in Alzheimer's disease.

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Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

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Analysis of genetic polymorphisms in the transforming growth factor-beta1 gene and the risk of Alzheimer's disease.

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TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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The sequence of the two extra exons in rat preA4.

21 January 2018

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Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage.

21 January 2018

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

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The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia

21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

21 January 2018

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Molecular cloning of the promoter of the gene encoding the Rhesus monkey beta-amyloid precursor protein: structural characterization and a comparative study with other species.

21 January 2018

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Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures.

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21 January 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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Mechanism of activation of the TGF-beta receptor

21 January 2018

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Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes.

21 January 2018

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Characterization of functional domains within Smad4/DPC4

21 January 2018

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DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells

21 January 2018

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Chimeric extracellular domain type II transforming growth factor (TGF)-beta receptor fused to the Fc region of human immunoglobulin as a TGF-beta antagonist

21 January 2018

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Deposition of amyloid beta protein in non-Alzheimer dementias: evidence for a neuronal origin of parenchymal deposits of beta protein in neurodegenerative disease.

21 January 2018

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Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes

21 January 2018

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Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

21 January 2018

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Transforming growth factor-beta is a survival factor for neonate cortical neurons: coincident expression of type I receptors in developing cerebral cortices.

21 January 2018

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Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

21 January 2018

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Regulation of beta-amyloid precursor protein isoform mRNAs by transforming growth factor-beta 1 and interleukin-1 beta in astrocytes

21 January 2018

1 reference

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TGF-beta(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization

21 January 2018

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Analysis of the 5'-flanking region of the beta-amyloid precursor protein gene that contributes to increased promoter activity in differentiated neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300819200

21 January 2018

Identifiers

DOI

10.1074/JBC.M300819200

1 reference

11 February 2018

1 reference

11 February 2018