(Q46665249)

24 December 2017

title

Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes (English)

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24 December 2017

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3

Mucke L

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24 December 2017

author name string

Zhao J

1

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24 December 2017

Paganini L

2

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24 December 2017

Gordon M

4

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24 December 2017

Refolo L

5

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24 December 2017

Carman M

6

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24 December 2017

Sinha S

7

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24 December 2017

Oltersdorf T

8

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24 December 2017

Lieberburg I

9

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24 December 2017

McConlogue L

10

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24 December 2017

language of work or name

English

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publication date

1 December 1996

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

271

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24 December 2017

issue

49

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24 December 2017

page(s)

31407-31411

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24 December 2017

Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

cites work

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Normal and abnormal biology of the beta-amyloid precursor protein

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Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

21 January 2018

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Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

21 January 2018

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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Alzheimer's disease: a central role for amyloid

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

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Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

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Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

21 January 2018

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Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control

21 January 2018

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A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

21 January 2018

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Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

21 January 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

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Cell-type and amyloid precursor protein-type specific inhibition of A beta release by bafilomycin A1, a selective inhibitor of vacuolar ATPases

21 January 2018

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Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

21 January 2018

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Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

21 January 2018

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Formation of beta-amyloid protein deposits in brains of transgenic mice

21 January 2018

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Heterologous introns can enhance expression of transgenes in mice

21 January 2018

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The simian virus 40 small-t intron, present in many common expression vectors, leads to aberrant splicing

21 January 2018

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A generic intron increases gene expression in transgenic mice

21 January 2018

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Molecular profile of reactive astrocytes--implications for their role in neurologic disease

21 January 2018

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Expression of APP in the early stage of brain damage.

21 January 2018

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Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex.

21 January 2018

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Indicator expression directed by regulatory sequences of the glial fibrillary acidic protein (GFAP) gene: in vivo comparison of distinct GFAP-lacZ transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.49.31407

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

21 January 2018

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Alzheimer's disease neuropathology. Current status of interpretation of lesion development

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.49.31407

1 reference

24 December 2017

1 reference

24 December 2017