(Q38260971)

1 September 2017

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title

25-Hydroxycholesterols in innate and adaptive immunity (English)

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1 September 2017

Jason G Cyster

1

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1 September 2017

Eric V Dang

series ordinal

2

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1 September 2017

Andrea Reboldi

series ordinal

3

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1 September 2017

Tangsheng Yi

series ordinal

4

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1 September 2017

language of work or name

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17 October 2014

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Nature Reviews Immunology

1 September 2017

published in

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1 September 2017

volume

14

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1 September 2017

issue

11

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1 September 2017

page(s)

731-743

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https://scigraph.springernature.com/pub.10.1038/nri3755

1 September 2017

exact match

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Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses

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EBI2 mediates B cell segregation between the outer and centre follicle

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Oxysterols direct immune cell migration via EBI2

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Oxysterols direct B-cell migration through EBI2

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ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation

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25-Hydroxycholesterol acts as an amplifier of inflammatory signaling

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25-Hydroxycholesterol enhances cytokine release and Toll-like receptor 3 response in airway epithelial cells.

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Cholesterol is required for infection by Semliki Forest virus

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25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

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25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

31 March 2020

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31 March 2020

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31 March 2020

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Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor

31 March 2020

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B cell localization: regulation by EBI2 and its oxysterol ligand

31 March 2020

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EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues

31 March 2020

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EBI2 operates independently of but in cooperation with CXCR5 and CCR7 to direct B cell migration and organization in follicles and the germinal center

31 March 2020

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Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles

31 March 2020

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B cell follicles and antigen encounters of the third kind

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells

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Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages.

31 March 2020

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31 March 2020

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Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1.

31 March 2020

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31 March 2020

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Autoimmune disease complicating antiviral therapy for hepatitis C virus infection

31 March 2020

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31 March 2020

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31 March 2020

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A murid gamma-herpesviruses exploits normal splenic immune communication routes for systemic spread.

31 March 2020

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

31 March 2020

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Integration of metabolism and inflammation by lipid-activated nuclear receptors

31 March 2020

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Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma

31 March 2020

1 reference

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.

31 March 2020

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Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

31 March 2020

1 reference

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

31 March 2020

1 reference

Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors

31 March 2020

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12 December 2020

3-Hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured fibroblasts from patients with mevalonate kinase deficiency: differential response to lipid supplied by fetal bovine serum in tissue culture medium

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12 December 2020

The cholesterol requirement for sindbis virus entry and exit and characterization of a spike protein region involved in cholesterol dependence

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12 December 2020

Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol

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12 December 2020

The antigen presenting cells instruct plasma cell differentiation

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12 December 2020

Esterification of oxysterols in human serum: effects on distribution and cellular uptake

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12 December 2020

Inhibition of Sterol Synthesis in Cultured Mouse Cells by Cholesterol Derivatives Oxygenated in the Side Chain

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12 December 2020

Regulation of cholesterol biosynthesis and esterification by 25-hydroxycholesterol in a macrophage-like cell line: uncoupling by progesterone

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12 December 2020

Cholesterol ester formation in cultured human fibroblasts. Stimulation by oxygenated sterols

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12 December 2020

Patterns of Epstein-Barr virus infection in non-neoplastic lymphoid tissue

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12 December 2020

Identifiers

DOI

10.1038/NRI3755

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Dimensions Publication ID

1 September 2017

1018666890

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