(Q38261558)

1 September 2017

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title

Autophagy as a pro-death pathway (English)

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1 September 2017

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3

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1 September 2017

Donna Denton

1

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author name string

Tianqi Xu

series ordinal

2

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1 September 2017

21 October 2014

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Immunology & Cell Biology

1 September 2017

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1 September 2017

93

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1 September 2017

35-42

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1 September 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/icb.2014.85

1 September 2017

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Apoptosis: controlled demolition at the cellular level

21 January 2018

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Caspase functions in cell death and disease

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Caspase function in programmed cell death

21 January 2018

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Death receptor-ligand systems in cancer, cell death, and inflammation

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy in protein and organelle turnover

21 January 2018

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The machinery of macroautophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Eaten alive: a history of macroautophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

TOR-dependent control of autophagy: biting the hand that feeds

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

The regulation of autophagy - unanswered questions

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

The morphology of various types of cell death in prenatal tissues

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Regulation and function of autophagy during cell survival and cell death.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Cell death by autophagy: facts and apparent artefacts

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagic cell death: the story of a misnomer

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagic cell death: Loch Ness monster or endangered species?

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagic cell death: analysis in Dictyostelium

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Atg1 allows second-signaled autophagic cell death in Dictyostelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.85

Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Starvation activates MAP kinase through the muscarinic acetylcholine pathway in Caenorhabditis elegans pharynx

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy activity contributes to programmed cell death in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Role and regulation of starvation-induced autophagy in the Drosophila fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy, not apoptosis, is essential for midgut cell death in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy functions in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy promotes caspase-dependent cell death during Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Developmentally programmed cell death in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

UTX coordinates steroid hormone-mediated autophagy and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Steroid regulation of midgut cell death during Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Larval midgut destruction in Drosophila: not dependent on caspases but suppressed by the loss of autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Uba1 functions in Atg7- and Atg3-independent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

The role of autophagy in mammalian development: cell makeover rather than cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

ATG proteins mediate efferocytosis and suppress inflammation in mammary involution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autosis: a new addition to the cell death Tower of Babel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Self-consumption: the interplay of autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Caspase 8 inhibits programmed necrosis by processing CYLD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Deconvoluting the context-dependent role for autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy in human health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

The role of autophagy in cancer development and response to therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Control of autophagic cell death by caspase-10 in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Cancer therapy beyond apoptosis: autophagy and anoikis as mechanisms of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

p53 status determines the role of autophagy in pancreatic tumour development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy genes in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

A critical role for the autophagy gene Atg5 in T cell survival and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy is essential for mitochondrial clearance in mature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Human immunodeficiency virus type-1 infection inhibits autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagy and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Pyroptosis: host cell death and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Control of infection by pyroptosis and autophagy: role of TLR and NLR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Molecular mechanism of SAHA on regulation of autophagic cell death in tamoxifen-resistant MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Dual inhibitor of phosphoinositide 3-kinase/mammalian target of rapamycin NVP-BEZ235 effectively inhibits cisplatin-resistant urothelial cancer cell growth through autophagic flux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Dasatinib induces autophagic cell death in human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

HDAC1 inactivation induces mitotic defect and caspase-independent autophagic cell death in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Cardiac glycoside ouabain induces autophagic cell death in non-small cell lung cancer cells via a JNK-dependent decrease of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Clioquinol induces pro-death autophagy in leukemia and myeloma cells by disrupting the mTOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Iron chelators induce autophagic cell death in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

Thymoquinone induces cell death in human squamous carcinoma cells via caspase activation-dependent apoptosis and LC3-II activation-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

A SAGE Approach to Discovery of Genes Involved in Autophagic Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

21 January 2018

1 reference

12 December 2020

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

1 reference

12 December 2020

The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line

1 reference

12 December 2020

Zoledronic acid induces autophagic cell death in human prostate cancer cells

1 reference

12 December 2020

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

1 reference

12 December 2020

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

1 reference

12 December 2020

A second signal for autophagic cell death?

1 reference

12 December 2020

Steroid regulated programmed cell death during Drosophila metamorphosis.

1 reference

12 December 2020

Increased Ras expression and caspase-independent neuroblastoma cell death: possible mechanism of spontaneous neuroblastoma regression

1 reference

12 December 2020

The autophagy gene ATG5 plays an essential role in B lymphocyte development

1 reference

12 December 2020

Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death

1 reference

12 December 2020

Autophagy in Human Health and Disease

1 reference

12 December 2020

Ursolic acid promotes cancer cell death by inducing Atg5-dependent autophagy

1 reference

12 December 2020

Shrinkage necrosis: a distinct mode of cellular death.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.85

7 January 2021

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Identifiers

DOI

10.1038/ICB.2014.85

1 reference

PubMed ID

25331550

Dimensions Publication ID

1 September 2017

1036392971

0 references

Fatcat ID

release_ev3vys36lzbfjlzl3isgryrqeu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ev3vys36lzbfjlzl3isgryrqeu

24 November 2022

mapped directly with Wikidata item

PubMed ID

25331550

1 reference

PubMed ID

25331550