(Q38268519)

1 September 2017

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title

Invited review: Prion-like transmission and spreading of tau pathology (English)

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1 September 2017

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F Clavaguera

1

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1 September 2017

J Hench

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2

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1 September 2017

M Goedert

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3

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1 September 2017

M Tolnay

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4

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1 September 2017

1 February 2015

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Neuropathology and Applied Neurobiology

1 September 2017

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1 September 2017

41

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1 September 2017

1

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1 September 2017

47-58

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 September 2017

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The propagation of prion-like protein inclusions in neurodegenerative diseases

21 January 2018

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Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

21 January 2018

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

21 January 2018

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Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study.

21 January 2018

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Abnormal Tau proteins in progressive supranuclear palsy. Similarities and differences with the neurofibrillary degeneration of the Alzheimer type.

21 January 2018

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Argyrophilic grain disease is a sporadic 4-repeat tauopathy

21 January 2018

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Abnormal tau-containing filaments in neurodegenerative diseases

21 January 2018

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Astrocytes expressing hyperphosphorylated tau protein without glial fibrillary tangles in argyrophilic grain disease.

21 January 2018

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Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies

21 January 2018

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Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy

21 January 2018

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Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue

21 January 2018

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Astrocytic plaques and tufts of abnormal fibers do not coexist in corticobasal degeneration and progressive supranuclear palsy

21 January 2018

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Frontotemporal lobar degeneration--tau as a pied piper?

21 January 2018

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Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment.

21 January 2018

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

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Tau is a candidate gene for chromosome 17 frontotemporal dementia

21 January 2018

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Neuropathological stageing of Alzheimer-related changes

21 January 2018

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Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

21 January 2018

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Transmission and spreading of tauopathy in transgenic mouse brain

21 January 2018

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Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

21 January 2018

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Propagation of tau pathology in a model of early Alzheimer's disease

21 January 2018

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Trans-synaptic spread of tau pathology in vivo

21 January 2018

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Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

21 January 2018

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"Prion-like" templated misfolding in tauopathies

21 January 2018

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A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

21 January 2018

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Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

21 January 2018

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Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice

21 January 2018

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In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice

21 January 2018

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Physiological release of endogenous tau is stimulated by neuronal activity.

21 January 2018

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Neuronal activity regulates extracellular tau in vivo

21 January 2018

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Ectosomes: a new mechanism for non-exosomal secretion of tau protein

21 January 2018

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Propagation of tau misfolding from the outside to the inside of a cell.

21 January 2018

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Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases

21 January 2018

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Conformational diversity of wild-type Tau fibrils specified by templated conformation change

21 January 2018

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A nucleated assembly mechanism of Alzheimer paired helical filaments

21 January 2018

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Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

21 January 2018

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Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

21 January 2018

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Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes

21 January 2018

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Brain homogenates from human tauopathies induce tau inclusions in mouse brain

21 January 2018

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Distinct tau prion strains propagate in cells and mice and define different tauopathies

21 January 2018

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A century of Alzheimer's disease

21 January 2018

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100 years of Lewy pathology.

21 January 2018

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Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

21 January 2018

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Purified and synthetic Alzheimer's amyloid beta (Aβ) prions

21 January 2018

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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

21 January 2018

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Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients

21 January 2018

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Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

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Prion-like acceleration of a synucleinopathy in a transgenic mouse model.

21 January 2018

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Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

21 January 2018

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Structural and functional characterization of two alpha-synuclein strains

21 January 2018

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Distinct α-synuclein strains differentially promote tau inclusions in neurons

21 January 2018

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Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis

21 January 2018

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Multiple factors contribute to the peripheral induction of cerebral β-amyloidosis.

21 January 2018

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.

21 January 2018

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Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

21 January 2018

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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

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Prion-like spreading of pathological α-synuclein in brain

21 January 2018

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Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

21 January 2018

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SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

21 January 2018

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MSUT2 is a determinant of susceptibility to tau neurotoxicity

21 January 2018

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The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?

21 January 2018

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Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity

21 January 2018

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Zinc binding directly regulates tau toxicity independent of tau hyperphosphorylation

21 January 2018

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Spreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegans

21 January 2018

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Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.

21 January 2018

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Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/NAN.12197

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1 September 2017

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