(Q48278741)

10 February 2018

review article

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title

100 years of Lewy pathology. (English)

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10 February 2018

main subject

pathology

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author

Maria Grazia Spillantini

2

object named as

Maria Grazia Spillantini

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10 February 2018

author name string

Michel Goedert

1

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10 February 2018

Kelly Del Tredici

3

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10 February 2018

Heiko Braak

4

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10 February 2018

language of work or name

English

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publication date

27 November 2012

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10 February 2018

published in

Nature Reviews Neurology

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10 February 2018

volume

9

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10 February 2018

issue

1

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10 February 2018

page(s)

13-24

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10 February 2018

https://scigraph.springernature.com/pub.10.1038/nrneurol.2012.242

exact match

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cites work

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The fold of alpha-synuclein fibrils

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alpha-Synuclein is phosphorylated in synucleinopathy lesions

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Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

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31 March 2020

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31 March 2020

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Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

31 March 2020

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Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

31 March 2020

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Lewy pathology and neurodegeneration in premotor Parkinson's disease

31 March 2020

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Parkinson's disease is not associated with gastrointestinal myenteric ganglion neuron loss

31 March 2020

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Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases

31 March 2020

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31 March 2020

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31 March 2020

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

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Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease

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A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death

31 March 2020

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Cell biology. A unifying role for prions in neurodegenerative diseases

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A timeline for Parkinson's disease

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Occurrence of Parkinson's syndrome in type I Gaucher disease

31 March 2020

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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

31 March 2020

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The incidence of Parkinsonism in patients with type 1 Gaucher disease: data from the ICGG Gaucher Registry

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Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders

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Exploring the link between glucocerebrosidase mutations and parkinsonism

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Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

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Lrrk2 and Lewy body disease

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

31 March 2020

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

31 March 2020

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

31 March 2020

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31 March 2020

Mechanisms of mitophagy

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

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Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

31 March 2020

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PINK1-linked parkinsonism is associated with Lewy body pathology

31 March 2020

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Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).

31 March 2020

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Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

31 March 2020

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Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

31 March 2020

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

31 March 2020

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SNCA variants are associated with increased risk for multiple system atrophy

31 March 2020

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Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

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αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

31 March 2020

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Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra

31 March 2020

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α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies

31 March 2020

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

31 March 2020

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Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

31 March 2020

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E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment

31 March 2020

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Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

31 March 2020

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SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease

31 March 2020

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

31 March 2020

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Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

31 March 2020

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Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

31 March 2020

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alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

31 March 2020

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Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons

31 March 2020

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Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities

31 March 2020

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A Drosophila model of Parkinson's disease

31 March 2020

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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

31 March 2020

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Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

31 March 2020

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Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

31 March 2020

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A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C . elegans

31 March 2020

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Small molecule inhibitors of alpha-synuclein filament assembly

31 March 2020

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

31 March 2020

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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

31 March 2020

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

31 March 2020

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

31 March 2020

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Prion-like acceleration of a synucleinopathy in a transgenic mouse model.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.242

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

31 March 2020

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Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

31 March 2020

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

31 March 2020

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Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

31 March 2020

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Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

31 March 2020

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Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system

31 March 2020

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Aromatic Amino Acids and Modification of Parkinsonism

31 March 2020

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Parkinsonism: onset, progression, and mortality

31 March 2020

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L-dopa in postencephalitic parkinsonism.

31 March 2020

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Olfactory function in patients with Parkinson's disease

31 March 2020

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Presenile dementia with Alzheimer-, Pick- and Lewy-body changes

31 March 2020

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

31 March 2020

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Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

31 March 2020

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Association of the human leucocyte antigen region with susceptibility to Parkinson's disease

31 March 2020

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Stanley Fahn Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered

31 March 2020

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Pathology associated with sporadic Parkinson's disease--where does it end?

31 March 2020

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12 December 2020

Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease

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12 December 2020

Neuroanatomy and pathology of sporadic Parkinson's disease.

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12 December 2020

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12 December 2020

Esophageal Lewy bodies associated with ganglion cell loss in achalasia. Similarity to Parkinson's disease

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12 December 2020

Relationship of neighboring tissue and gliosis to α-synuclein pathology in a fetal transplant for Parkinson's disease

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12 December 2020

Overview of the extranigral aspects of Parkinson disease

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12 December 2020

Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model

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12 December 2020

The first autopsied case of diffuse Lewy body disease (DLBD): re-examination by recent immunostaining methods: The 50th Anniversary of Japanese Society of Neuropathology

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12 December 2020

Disentangling the relationship between lewy bodies and nigral neuronal loss in Parkinson's disease

1 reference

12 December 2020

Chronic behavioral disorders of human REM sleep: a new category of parasomnia

1 reference

12 December 2020

1 reference

12 December 2020

10.1038/NRNEUROL.2012.242

Identifiers

DOI

1 reference

10 February 2018

1 reference

10 February 2018