(Q48586171)

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Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

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scholarly article

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16611810

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673887&resulttype=core&format=json

11 May 2020

1 reference

based on heuristic

inferred from title

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substantia nigra

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based on heuristic

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George K Tofaris

1

1 reference

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11 May 2020

Pablo Garcia-Reitböck

2

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11 May 2020

3

1 reference

Europe PubMed Central

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11 May 2020

Maria Grazia Spillantini

11

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Maria Grazia Spillantini

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11 May 2020

Bernardino F. Ghetti

6

object named as

Bernardino Ghetti

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11 May 2020

author name string

Sarah L Lambourne

4

1 reference

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11 May 2020

Mark O'Connell

5

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11 May 2020

Helen Gossage

7

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11 May 2020

Piers C Emson

8

1 reference

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11 May 2020

Lawrence S Wilkinson

9

1 reference

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11 May 2020

Michel Goedert

10

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11 May 2020

language of work or name

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publication date

1 April 2006

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16611810

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673887&resulttype=core&format=json

11 May 2020

26

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11 May 2020

15

1 reference

Europe PubMed Central

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11 May 2020

3942-3950

1 reference

Europe PubMed Central

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11 May 2020

Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

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https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of Insoluble α-Synuclein in Dementia with Lewy Bodies

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https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology in mice expressing human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein and neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dopamine receptor signaling and dopamine receptor-G protein coupling in denervated striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Cellular polyamines promote the aggregation of alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoproteolytic activity of the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Polycation-induced oligomerization and accelerated fibrillation of human alpha-synuclein in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

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Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early-onset dementia with Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Olfaction and Parkinson's syndromes: its role in differential diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common genetic effects on variation in impulsivity and activity in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional distribution of proteinase K-resistant alpha-synuclein correlates with Lewy body disease stage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of p-chlorophenylalanine on release of 5-hydroxytryptamine from the rat frontal cortex in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5' upstream DNA sequence of the rat tyrosine hydroxylase gene directs high-level and tissue-specific expression to catecholaminergic neurons in the central nervous system of transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two distinct synucleins from human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein in Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical aspects of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic filaments assembled from C-terminally truncated alpha-synuclein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16611810

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4965-05.2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673887&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673887&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673887&resulttype=core&format=json

11 May 2020

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