(Q38288542)

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Human topoisomerase IIalpha possesses an intrinsic nucleic acid specificity for DNA ligation. Use of 5' covalently activated oligonucleotide substrates to study enzyme mechanism

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Europe PubMed Central

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1 September 2017

Human topoisomerase IIalpha possesses an intrinsic nucleic acid specificity for DNA ligation. Use of 5' covalently activated oligonucleotide substrates to study enzyme mechanism (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

4

object named as

Neil Osheroff

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Europe PubMed Central

PubMed publication ID

1 September 2017

3

object named as

Alex B Burgin

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Europe PubMed Central

PubMed publication ID

1 September 2017

author name string

Kenneth D Bromberg

1

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Europe PubMed Central

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1 September 2017

Chris Hendricks

2

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Europe PubMed Central

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1 September 2017

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publication date

5 June 2002

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Europe PubMed Central

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1 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

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1 September 2017

277

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Europe PubMed Central

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1 September 2017

34

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Europe PubMed Central

PubMed publication ID

1 September 2017

31201-31206

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Europe PubMed Central

PubMed publication ID

1 September 2017

DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

DNA topoisomerases: structure, function, and mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Structure of DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Mutagenic properties of topoisomerase-targeted drugs.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Tumor cell death induced by topoisomerase-targeting drugs.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

The critical role of chromosome translocations in human leukemias.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Calcium-promoted DNA cleavage by eukaryotic topoisomerase II: trapping the covalent enzyme-DNA complex in an active form.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Vaccinia topoisomerase and Cre recombinase catalyze direct ligation of activated DNA substrates containing a 3'-para-nitrophenyl phosphate ester

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Positioning the 3'-DNA terminus for topoisomerase II-mediated religation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

DNA topoisomerase II is required at the time of mitosis in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Apurinic sites are position-specific topoisomerase II poisons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Drosophila topoisomerase II double-strand DNA cleavage: analysis of DNA sequence homology at the cleavage site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

DNA sequence selectivity of topoisomerases and topoisomerase poisons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Cell death induced by topoisomerase-targeted drugs: more questions than answers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Catalytic inhibitors of DNA topoisomerase II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Secondary leukemias induced by topoisomerase-targeted drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Clinical applications of anticancer drugs targeted to topoisomerase II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

DNA cleavage and religation by human topoisomerase II alpha at high temperature

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204741200

21 January 2018

Identifiers

10.1074/JBC.M204741200

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

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