(Q38303919)

1 September 2017

The mutagenic potential of non-homologous end joining in the absence of the NHEJ core factors Ku70/80, DNA-PKcs and XRCC4-LigIV. (English)

1 reference

1 September 2017

Steffi Kuhfittig-Kulle

1

1 reference

1 September 2017

Elke Feldmann

2

1 reference

1 September 2017

Andrea Odersky

3

1 reference

1 September 2017

Aneta Kuliczkowska

4

1 reference

1 September 2017

Wolfgang Goedecke

5

1 reference

1 September 2017

Angelika Eggert

6

1 reference

1 September 2017

Petra Pfeiffer

7

1 reference

1 September 2017

7 March 2007

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1 September 2017

1 reference

1 September 2017

22

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1 September 2017

217-233

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1 September 2017

3

1 reference

Chromosomal stability and the DNA double-stranded break connection

1 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Pathways of DNA double-strand break repair and their impact on the prevention and formation of chromosomal aberrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Mechanism of DNA double-strand break repair by non-homologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Pathways of DNA double-strand break repair during the mammalian cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Ku, a DNA repair protein with multiple cellular functions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

The DNA-dependent protein kinase: the director at the end.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

A biochemically defined system for mammalian nonhomologous DNA end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Repair of double-strand DNA breaks by the human nonhomologous DNA end joining pathway: the iterative processing model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Severe combined immunodeficiency and microcephaly in siblings with hypomorphic mutations in DNA ligase IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

An overview of three new disorders associated with genetic instability: LIG4 syndrome, RS-SCID and ATR-Seckel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA double-strand break repair: a relentless hunt uncovers new prey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Rejoining of DNA double-strand breaks in vitro by single-strand annealing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Double-strand break repair in Ku86- and XRCC4-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Biochemical evidence for Ku-independent backup pathways of NHEJ

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Backup pathways of NHEJ are suppressed by DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Modulation of DNA end joining by nuclear proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Cancer susceptibility and the functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA ligase III as a candidate component of backup pathways of nonhomologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Mechanisms of overlap formation in nonhomologous DNA end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Molecular and biochemical characterization of xrs mutants defective in Ku80.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Ku-dependent nonhomologous DNA end joining in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

A paradox in the in vitro end-joining assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Chromosomal double-strand break repair in Ku80-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Joining of nonhomologous DNA double strand breaks in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Resolution and conservation of mismatches in DNA end joining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

A novel pathway of DNA end-to-end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Cloning, purification and characterization of DNA polymerase beta from Xenopus laevis--studies on its potential role in DNA-end joining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA end-joining catalyzed by human cell-free extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Distinct requirements for Ku in N nucleotide addition at V(D)J- and non-V(D)J-generated double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Mechanisms of nonhomologous recombination in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Absence of major defects in non-homologous DNA end joining in human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Repair of sequence-specific 125I-induced double-strand breaks by nonhomologous DNA end joining in mammalian cell-free extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Processing of DNA for nonhomologous end-joining by cell-free extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Nonhomologous DNA end joining in cell-free systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Ku recruits the XRCC4-ligase IV complex to DNA ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

The role of BRCA1 in non-homologous end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

DNA end joining becomes less efficient and more error-prone during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEM007

21 January 2018

Identifiers

DOI

10.1093/MUTAGE/GEM007

1 reference

1 September 2017

1 reference