(Q38305480)

2 September 2017

title

Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop (English)

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heparan sulfate proteoglycans

2 September 2017

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Lorraine M Work

7

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Stuart A Nicklin

object named as

Stuart A Nicklin

9

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John H. McVey

object named as

John H McVey

8

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author name string

Angelika B Kritz

1

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2 September 2017

Campbell G Nicol

2

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2 September 2017

Kate L Dishart

3

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2 September 2017

Ruth Nelson

4

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2 September 2017

Susan Holbeck

5

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2 September 2017

Dan J Von Seggern

6

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2 September 2017

Andrew H Baker

10

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2 September 2017

publication date

23 January 2007

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2 September 2017

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2 September 2017

volume

15

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2 September 2017

issue

4

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2 September 2017

page(s)

741-749

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Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

2 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

The influence of adenovirus fiber structure and function on vector development for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Crystal structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

CAR- or alphav integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Adenovirus type 5 viral particles pseudotyped with mutagenized fiber proteins show diminished infectivity of coxsackie B-adenovirus receptor-bearing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Infectivity-enhanced cyclooxygenase-2-based conditionally replicative adenoviruses for esophageal adenocarcinoma treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Identification of PDGFR as a receptor for AAV-5 transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Role of the putative heparan sulfate glycosaminoglycan-binding site of the adenovirus type 5 fiber shaft on liver detargeting and knob-mediated retargeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Complementation of a fibre mutant adenovirus by packaging cell lines stably expressing the adenovirus type 5 fibre protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300094

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300094

1 reference

2 September 2017

1 reference