(Q38309242)

2 September 2017

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title

Targeting microRNAs in epithelial-to-mesenchymal transition-induced cancer stem cells: therapeutic approaches in cancer (English)

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2 September 2017

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neoplastic stem cells

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Minal Garg

1

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PubMed ID

25563894

2 September 2017

language of work or name

English

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publication date

7 January 2015

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Expert Opinion on Therapeutic Targets

2 September 2017

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2 September 2017

19

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2 September 2017

2

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2 September 2017

285-297

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Epithelial mesenchymal transition from a natural gestational orchestration to a bizarre cancer disturbance

2 September 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Salinomycin as a drug for targeting human cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The basics of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Complex networks orchestrate epithelial-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Ubiquitination and the Ubiquitin-Proteasome System as regulators of transcription and transcription factors in epithelial mesenchymal transition of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Biomarkers for epithelial-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Epithelial-mesenchymal transition - activating transcription factors - multifunctional regulators in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The snail superfamily of zinc-finger transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

New role of microRNA: carcinogenesis and clinical application in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Metastasis: from dissemination to organ-specific colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Regulation of EMT by TGFβ in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA-191, by promoting the EMT and increasing CSC-like properties, is involved in neoplastic and metastatic properties of transformed human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

let-7 regulates self renewal and tumorigenicity of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

miR-34 - a microRNA replacement therapy is headed to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The promise of microRNA replacement therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

microRNA therapies in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Regression of murine lung tumors by the let-7 microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The let-7 microRNA reduces tumor growth in mouse models of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA-181a

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Expression of miR-106b-25 induced by salvianolic acid B inhibits epithelial-to-mesenchymal transition in HK-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

α-Solanine inhibits invasion of human prostate cancer cell by suppressing epithelial-mesenchymal transition and MMPs expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Targeted delivery of miR-200c/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Progress in microRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Oncofetal H19 RNA promotes tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Targeting of the signal transducer Smo links microRNA-326 to the oncogenic Hedgehog pathway in CD34+ CML stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Enrichment of ovarian cancer stem-like cells is associated with epithelial to mesenchymal transition through an miRNA-activated AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA-106b modulates epithelial-mesenchymal transition by targeting TWIST1 in invasive endometrial cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

An integrated expression profiling reveals target genes of TGF-β and TNF-α possibly mediated by microRNAs in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Targets of miR-200c mediate suppression of cell motility and anoikis resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

MiR-145 regulates cancer stem-like properties and epithelial-to-mesenchymal transition in lung adenocarcinoma-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.975794

10.1517/14728222.2014.975794

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

25563894