(Q37991651)

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Ubiquitination and the Ubiquitin-Proteasome System as regulators of transcription and transcription factors in epithelial mesenchymal transition of cancer

scientific article published on 06 March 2012

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Europe PubMed Central

PubMed publication ID

26 August 2017

Ubiquitination and the Ubiquitin-Proteasome System as regulators of transcription and transcription factors in epithelial mesenchymal transition of cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

ubiquitin-proteasome system

0 references

protein ubiquitination

1 reference

based on heuristic

inferred from title

Ioannis A. Voutsadakis

1

object named as

Ioannis A Voutsadakis

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

6 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

33

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

897-910

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

Complex networks orchestrate epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Unraveling the complexity of ubiquitin signaling

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Constructing and decoding unconventional ubiquitin chains.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Histone methylation and ubiquitination with their cross-talk and roles in gene expression and stability

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The basics of epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Biomarkers for epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The fallacy of epithelial mesenchymal transition in neoplasia

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Hallmarks of Cancer: The Next Generation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Adherens junctions: from molecules to morphogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Adherens junction: molecular architecture and regulation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

RING domain E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Polyubiquitin chains: functions, structures, and mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Mechanism and function of deubiquitinating enzymes

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The proteasome: a proteolytic nanomachine of cell regulation and waste disposal

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Signaling to NF-kappaB: regulation by ubiquitination

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

NF-kappaB and epithelial to mesenchymal transition of cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The TAK1-TRAF6 signalling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

NF-kappaB-dependent plasticity of the epithelial to mesenchymal transition induced by Von Hippel-Lindau inactivation in renal cell carcinomas

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Mechanism of transcriptional activation by the Myc oncoproteins

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

IκB kinases increase Myc protein stability and enhance progression of breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Context matters: the hen or egg problem in Ewing's sarcoma.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Microarray analysis of PDGFR alpha+ populations in ES cell differentiation culture identifies genes involved in differentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

PEA3 is necessary for optimal epidermal growth factor receptor-stimulated matrix metalloproteinase expression and invasion of ovarian tumor cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

COP1 is a tumour suppressor that causes degradation of ETS transcription factors

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Blinded by the Light: The Growing Complexity of p53

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

A novel HECT-type E3 ubiquitin ligase, NEDL2, stabilizes p73 and enhances its transcriptional activity

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Degradation of p63 by Itch.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p53 post-translational modification: deregulated in tumorigenesis

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

ZEB1-responsive genes in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Unraveling signalling cascades for the Snail family of transcription factors

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Epithelial-mesenchymal transition in ovarian cancer progression: a crucial role for the endothelin axis

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Glucocorticoid induces mesenchymal‐to‐epithelial transition and inhibits TGF‐β1‐induced epithelial‐to‐mesenchymal transition and cell migration

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Molecular predictors of gemcitabine response in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Hyaluronan-CD44 Interaction Promotes c-Src-mediated Twist Signaling, MicroRNA-10b Expression, and RhoA/RhoC Up-regulation, Leading to Rho-kinase-associated Cytoskeleton Activation and Breast Tumor Cell Invasion

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Twist is substrate for caspase cleavage and proteasome-mediated degradation.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

E2A protein degradation by the ubiquitin-proteasome system is stage-dependent during muscle differentiation.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Proteolytic and non-proteolytic roles of ubiquitin and the ubiquitin proteasome system in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Steroid receptor induction of gene transcription: a two-step model

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Transcriptional regulation by histone ubiquitination and deubiquitination.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Core histone H2A ubiquitylation and transcriptional regulation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

H2B ubiquitylation in transcriptional control: a FACT-finding mission

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Structural basis of eukaryotic gene transcription

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Removal of promoter nucleosomes by disassembly rather than sliding in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

A coregulatory role for the mediator complex in prostate cancer cell proliferation and gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Emerging roles of ubiquitin in transcription regulation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Breast cancer quality control.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Ras activity regulates cyclin E degradation by the Fbw7 pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The cullin7 E3 ubiquitin ligase: a novel player in growth control

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Induction of cullin 7 by DNA damage attenuates p53 function

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Parc: a cytoplasmic anchor for p53.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The regulation of the p53-mediated stress response by MDM2 and MDM4.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Mdm2-mediated ubiquitylation: p53 and beyond.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Mdm2 and Mdm4 loss regulates distinct p53 activities

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Targeting the ubiquitin-proteasome system to activate wild-type p53 for cancer therapy.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

MDM2 inhibitors for cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53-MDM2 protein-protein interaction

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0355-X

21 January 2018

E6-associated protein (E6-AP) is a dual function coactivator of steroid hormone receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative nuclear functions for NF-κB family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Snail promotes Wnt target gene expression and interacts with beta-catenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myc-modulated miR-9 makes more metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho GTPase function in tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyomavirus enhancer activator 3 protein promotes breast cancer metastatic progression through Snail-induced epithelial-mesenchymal transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HAUSP gene plays an important role in non-small cell lung carcinogenesis through p53-dependent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13277-012-0355-X

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 August 2017

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