(Q38310624)

2 September 2017

1 reference

title

Neurofilament dynamics and involvement in neurological disorders (English)

1 reference

2 September 2017

Benoit J Gentil

1

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author name string

Michael Tibshirani

series ordinal

2

1 reference

PubMed ID

25567110

2 September 2017

Heather D Durham

series ordinal

3

1 reference

2 September 2017

8 January 2015

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2 September 2017

Cell and Tissue Research

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2 September 2017

360

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2 September 2017

3

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2 September 2017

609-620

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https://scigraph.springernature.com/pub.10.1007/s00441-014-2082-7

2 September 2017

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cites work

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Heterodimeric associations between neuronal intermediate filament proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Individual microtubules in the axon consist of domains that differ in both composition and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Expansion of neurofilament medium C terminus increases axonal diameter independent of increases in conduction velocity or myelin thickness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Association of actin filaments with axonal microtubule tracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Squid axoplasm supports the retrograde axonal transport of herpes simplex virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Gel-expanded to gel-condensed transition in neurofilament networks revealed by direct force measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Phosphorylated neurofilament heavy subunit (pNF-H) in peripheral blood and CSF as a potential prognostic biomarker in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Neurofilament-L homopolymers are less mechanically stable than native neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Stochastic simulation of neurofilament transport in axons: the "stop-and-go" hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Neurofilaments are prominent in bullfrog olfactory axons but are rarely seen in those of the tiger salamander, Ambystoma tigrinum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Chemical cross-linking analyses of ox neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Proximal axonal enlargement in motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Neurofilament protein heterotetramers as assembly intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Intermediate filaments exchange subunits along their length and elongate by end-to-end annealing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Microtubule assembly, organization and dynamics in axons and dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Monitoring of S100 homodimerization and heterodimeric interactions by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Requirement of heavy neurofilament subunit in the development of axons with large calibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Giant axon and neurofilament accumulation in Charcot-Marie-Tooth disease type 2E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Charcot-Marie-Tooth disease type 2E, a disorder of the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Cytoplasmic actin in neuronal processes as a possible mediator of synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Cytoskeleton-associated plectin: in situ localization, in vitro reconstitution, and binding to immobilized intermediate filament proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Increased neurofilament light chain blood levels in neurodegenerative neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Isolation of nonobese diabetic mouse T-cells that recognize novel autoantigens involved in the early events of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Normal role of the low-molecular-weight neurofilament protein in mitochondrial dynamics and disruption in Charcot-Marie-Tooth disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Heterogeneity in the properties of NEFL mutants causing Charcot-Marie-Tooth disease results in differential effects on neurofilament assembly and susceptibility to intervention by the chaperone-inducer, celastrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A two-hybrid screen identifies an unconventional role for the intermediate filament peripherin in regulating the subcellular distribution of the SNAP25-interacting protein, SIP30

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

miRNA malfunction causes spinal motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

The coiled coil of in vitro assembled keratin filaments is a heterodimer of type I and II keratins: use of site-specific mutagenesis and recombinant protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Axonal development in the cerebral white matter of the human fetus and infant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Intermediate filaments and their associates: multi-talented structural elements specifying cytoarchitecture and cytodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Phosphorylated high molecular weight neurofilament protein in the peripheral motor, sensory and sympathetic neuronal perikarya: system-dependent normal variations and changes in amyotrophic lateral sclerosis and multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Mutations in the neurofilament light chain gene (NEFL) cause early onset severe Charcot-Marie-Tooth disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Is a novel I214M substitution in the NEFL gene a cause of Charcot-Marie-Tooth disease? Functional analysis using cell culture models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Which way to go? Cytoskeletal organization and polarized transport in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Antagonistic roles of neurofilament subunits NF-H and NF-M against NF-L in shaping dendritic arborization in spinal motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Reduced number of unmyelinated sensory axons in peripherin null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Slow axonal transport mechanisms move neurofilaments relentlessly in mouse optic axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

No requirement of alpha-internexin for nervous system development and for radial growth of axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Purification of individual components of the neurofilament triplet: filament assembly from the 70 000-dalton subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Movement of mitochondria in the axons and dendrites of cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Cytoskeletal changes during development and aging in the cortex of neurofilament light protein knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Nesprins LINC the nucleus and cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Overexpression of USP14 protease reduces I-κB protein levels and increases cytokine release in lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Clinical and electrophysiological features in Charcot-Marie-Tooth disease with mutations in the NEFL gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Spontaneous and evoked neuronal activities regulate movements of single neuronal mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

ER vesicles and mitochondria move and communicate at synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Major phosphorylation site (Ser55) of neurofilament L by cyclic AMP-dependent protein kinase in rat primary neuronal culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Effects of Charcot-Marie-Tooth-linked mutations of the neurofilament light subunit on intermediate filament formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Ubiquitinated proteins activate the proteasomal ATPases by binding to Usp14 or Uch37 homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Evidence for antigen driven selection in two monoclonal auto-antibodies derived from nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Peripherin is a relevant neuroendocrine autoantigen recognized by islet-infiltrating B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

The myosin Va head domain binds to the neurofilament-L rod and modulates endoplasmic reticulum (ER) content and distribution within axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A neurotoxic peripherin splice variant in a mouse model of ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Axonal cytoskeletal pathology in aged and diabetic human sympathetic autonomic ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis-comparison between Onuf's neurons and other sacral motor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Mitochondrial and axonal abnormalities precede disruption of the neurofilament network in a model of charcot-marie-tooth disease type 2E and are prevented by heat shock proteins in a mutant-specific fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Neurofilaments switch between distinct mobile and stationary states during their transport along axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Regulation of peripherin and neurofilament expression in regenerating rat motor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Severing and end-to-end annealing of neurofilaments in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Carboxyl-terminus of Hsc70 interacting protein mediates 2,5-hexanedione-induced neurofilament medium chain degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Characterization of the in vitro co-assembly process of the intermediate filament proteins vimentin and desmin: mixed polymers at all stages of assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

An aggregate-inducing peripherin isoform generated through intron retention is upregulated in amyotrophic lateral sclerosis and associated with disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Neurofilament subunit (NFL) head domain phosphorylation regulates axonal transport of neurofilaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Deficiency of the E3 ubiquitin ligase TRIM2 in early-onset axonal neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

A novel recessive Nefl mutation causes a severe, early-onset axonal neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

In vitro reconstitution of intermediate filaments form mammalian neurofilament triplet polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

The novel neurofilament light (NEFL) mutation Glu397Lys is associated with a clinically and morphologically heterogeneous type of Charcot-Marie-Tooth neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Clinical and molecular findings in patients with giant axonal neuropathy (GAN)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2082-7

10.1007/S00441-014-2082-7

21 January 2018

Identifiers

DOI

1 reference

PubMed ID

25567110

Dimensions Publication ID

2 September 2017

0 references

1 reference

PubMed ID

25567110