(Q38325368)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25603899%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

review article

1 reference

title

Common single nucleotide variants underlying drug addiction: more than a decade of research (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25603899%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

1

1 reference

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28 February 2020

Víctor Echeverry-Alzate

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25603899%20AND%20SRC:MED&resulttype=core&format=json

José Antonio López-Moreno

28 February 2020

6

1 reference

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28 February 2020

author name string

Elena Giné

2

1 reference

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28 February 2020

Javier Calleja-Conde

4

1 reference

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28 February 2020

Fernando Rodriguez de Fonseca

5

1 reference

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28 February 2020

publication date

21 January 2015

1 reference

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28 February 2020

1 reference

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28 February 2020

volume

20

1 reference

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28 February 2020

issue

5

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28 February 2020

page(s)

845-871

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25603899%20AND%20SRC:MED&resulttype=core&format=json

A genome-wide association study of DSM-IV cannabis dependence

28 February 2020

cites work

1 reference

Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study

21 January 2018

1 reference

Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence

21 January 2018

1 reference

What is a functional genetic polymorphism? Defining classes of functionality

21 January 2018

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Mammalian nicotinic acetylcholine receptors: from structure to function

21 January 2018

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Genetic mapping in human disease

21 January 2018

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Integrating common and rare genetic variation in diverse human populations

21 January 2018

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The effects of cannabinoids on the brain

21 January 2018

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The role of endocannabinoid transmission in cocaine addiction

21 January 2018

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Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes

21 January 2018

1 reference

Addiction science and its genetics

21 January 2018

1 reference

The endocannabinoid system: an overview

21 January 2018

1 reference

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25.

21 January 2018

1 reference

A genome-wide association study of alcohol dependence

21 January 2018

1 reference

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry

21 January 2018

1 reference

Novel genes identified in a high-density genome wide association study for nicotine dependence

21 January 2018

1 reference

Variants in nicotinic receptors and risk for nicotine dependence

21 January 2018

1 reference

Allelic association of human dopamine D2 receptor gene in alcoholism

21 January 2018

1 reference

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction

21 January 2018

1 reference

Genetic polymorphism of alcohol dehydrogenase in europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1.

21 January 2018

1 reference

Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice

21 January 2018

1 reference

Risky alcohol consumption in young people is associated with the fatty acid amide hydrolase gene polymorphism C385A and affective rating of drug pictures.

21 January 2018

1 reference

Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation

21 January 2018

1 reference

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

21 January 2018

1 reference

The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women

21 January 2018

1 reference

Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use.

21 January 2018

1 reference

Scanning of genetic effects of alcohol metabolism gene (ADH1B and ADH1C) polymorphisms on the risk of alcoholism

21 January 2018

1 reference

Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis

21 January 2018

1 reference

Problems of reporting genetic associations with complex outcomes

21 January 2018

1 reference

Functional intronic polymorphisms: Buried treasure awaiting discovery within our genes

21 January 2018

1 reference

Allelic and haplotypic association of GABRA2 with alcohol dependence

21 January 2018

1 reference

Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors.

21 January 2018

1 reference

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

21 January 2018

1 reference

COMT val108/158 met genotype affects neural but not cognitive processing in healthy individuals

21 January 2018

1 reference

Genes, cognition and brain through a COMT lens

21 January 2018

1 reference

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

21 January 2018

1 reference

Genetic vulnerability to drug abuse.

21 January 2018

1 reference

Genetic approaches to addiction: genes and alcohol

21 January 2018

1 reference

Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations

21 January 2018

1 reference

Sex differences in the influence of COMT Val158Met on alcoholism and smoking in plains American Indians

21 January 2018

1 reference

Striatal α5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum.

21 January 2018

1 reference

Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues.

21 January 2018

1 reference

The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction

21 January 2018

1 reference

Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors

21 January 2018

1 reference

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

21 January 2018

1 reference

Human genetic variation and its contribution to complex traits

21 January 2018

1 reference

Overexpression of 5-HT(1B) mRNA in nucleus accumbens shell projection neurons differentially affects microarchitecture of initiation and maintenance of ethanol consumption

21 January 2018

1 reference

Selective role of glutathione in protecting human neuronal cells from dopamine-induced apoptosis

21 January 2018

1 reference

Alternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expression

21 January 2018

1 reference

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

21 January 2018

1 reference

Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene

21 January 2018

1 reference

Molecular characterization of human and mouse fatty acid amide hydrolases

21 January 2018

1 reference

Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample

21 January 2018

1 reference

Distribution of ADH2 and ALDH2 genotypes in different populations.

21 January 2018

1 reference

Genetics of dopamine receptors and drug addiction

21 January 2018

1 reference

Failure to replicate a genetic association may provide important clues about genetic architecture

21 January 2018

1 reference

A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence

21 January 2018

1 reference

Association of genetic variants in alcohol dehydrogenase 4 with alcohol dependence in Brazilian patients

21 January 2018

1 reference

Correlation of polymorphic variation in the promoter region of the interleukin-1 beta gene with secretion of interleukin-1 beta protein

21 January 2018

1 reference

Evidence of positive selection on a class I ADH locus

21 January 2018

1 reference

Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function

21 January 2018

1 reference

Marijuana withdrawal and craving: influence of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes.

21 January 2018

1 reference

Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression

21 January 2018

1 reference

Pharmacogenetic approaches to the treatment of alcohol addiction

21 January 2018

1 reference

Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families

21 January 2018

1 reference

Opioid modulators for alcohol dependence.

21 January 2018

1 reference

A comprehensive review of genetic association studies

21 January 2018

1 reference

C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo.

21 January 2018

1 reference

Association in alcoholic patients between psychopathic traits and the additive effect of allelic forms of the CNR1 and FAAH endocannabinoid genes, and the 3' region of the DRD2 gene

21 January 2018

1 reference

The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine.

21 January 2018

1 reference

Impact of interacting functional variants in COMT on regional gray matter volume in human brain

21 January 2018

1 reference

Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents

21 January 2018

1 reference

Serotonin 1B receptor imaging in alcohol dependence

21 January 2018

1 reference

GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans

21 January 2018

1 reference

Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice

21 January 2018

1 reference

Single-nucleotide polymorphism bioinformatics: a comprehensive review of resources

21 January 2018

1 reference

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

21 January 2018

1 reference

Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans

21 January 2018

1 reference

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers.

21 January 2018

1 reference

What psychiatric genetics has taught us about the nature of psychiatric illness and what is left to learn

21 January 2018

1 reference

Gender differences in the effects of ADH1B and ALDH2 polymorphisms on alcoholism

21 January 2018

1 reference

Functional implications of genetic variation in non-coding DNA for disease susceptibility and gene regulation

21 January 2018

1 reference

A role for GABA mechanisms in the motivational effects of alcohol

21 January 2018

1 reference

Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption

21 January 2018

1 reference

The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.

21 January 2018

1 reference

The A1 allele of the D2 dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics

21 January 2018

1 reference

Genetic dissection of complex traits

21 January 2018

1 reference

A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States

21 January 2018

1 reference

Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases

21 January 2018

1 reference

Drug addiction: pathways to the disease and pathophysiological perspectives

21 January 2018

1 reference

The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence.

21 January 2018

1 reference

Genes and (common) pathways underlying drug addiction

21 January 2018

1 reference

Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases

21 January 2018

1 reference

New insights into the genetics of addiction

21 January 2018

1 reference

GWASdb: a database for human genetic variants identified by genome-wide association studies

21 January 2018

1 reference

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

21 January 2018

1 reference

Protective effects of N-acetylcysteine in isoproterenol-induced myocardium injury in rats

21 January 2018

1 reference

The genetic basis of the endocannabinoid system and drug addiction in humans.

21 January 2018

1 reference

Association analysis of the GABA(A) receptor subunit genes cluster on 5q33-34 and alcohol dependence in a Japanese population.

21 January 2018

1 reference

Glutamate decarboxylase genes and alcoholism in Han Taiwanese men.

21 January 2018

1 reference

Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans

21 January 2018

1 reference

ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies

21 January 2018

1 reference

ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies

21 January 2018

1 reference

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis

21 January 2018

1 reference

Involvement of the endocannabinoid system in drug addiction

21 January 2018

1 reference

Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function

21 January 2018

1 reference

Genetic heterogeneity in human disease

21 January 2018

1 reference

The endocannabinoid system and the brain

21 January 2018

1 reference

The Role of Glial Cells in Drug Abuse.

21 January 2018

1 reference

Association of alcohol-metabolizing genes with alcoholism in a Mexican Indian (Otomi) population.

21 January 2018

1 reference

Alcohol-induced euphoria: exclusion of serotonin

21 January 2018

1 reference

Identification of functional SNPs in the 5-prime flanking sequences of human genes

21 January 2018

1 reference

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.

21 January 2018

1 reference

The genetic basis for smoking behavior: a systematic review and meta-analysis

21 January 2018

1 reference

Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data

21 January 2018

1 reference

Common molecular and cellular substrates of addiction and memory

21 January 2018

1 reference

Is there a common molecular pathway for addiction?

21 January 2018

1 reference

Alcohol dehydrogenase polymorphisms influence alcohol-elimination rates in a male Jewish population

21 January 2018

1 reference

Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1

21 January 2018

1 reference

D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes

21 January 2018

1 reference

Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism

21 January 2018

1 reference

A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain

21 January 2018

1 reference

The evolution and population genetics of the ALDH2 locus: random genetic drift, selection, and low levels of recombination

21 January 2018

1 reference

A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions

21 January 2018

1 reference

Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism

21 January 2018

1 reference

A proline-threonine substitution in codon 351 of ADH1C is common in Native Americans

21 January 2018

1 reference

A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients

21 January 2018

1 reference

The genetics of alcohol dependence: advancing towards systems-based approaches

21 January 2018

1 reference

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication

21 January 2018

1 reference

Association between alcoholism and the genetic polymorphisms of the GABAA receptor genes on chromosome 5q33-34 in Korean population

21 January 2018

1 reference

Candidate gene association studies: a comprehensive guide to useful in silico tools

21 January 2018

1 reference

A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research.

21 January 2018

1 reference

Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations

21 January 2018

1 reference

The pharmacology of cannabinoid receptors and their ligands: an overview

21 January 2018

1 reference

The molecular logic of endocannabinoid signalling

21 January 2018

1 reference

The endogenous cannabinoid system and the treatment of marijuana dependence

21 January 2018

1 reference

The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers

21 January 2018

1 reference

DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study

21 January 2018

1 reference

The ANKK1 kinase gene and psychiatric disorders.

21 January 2018

1 reference

Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study.

21 January 2018

1 reference

Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism

21 January 2018

1 reference

Human non-synonymous SNPs: server and survey

21 January 2018

1 reference

21 January 2018

1 reference

A polymorphism of the mu-opioid receptor gene (OPRM1) and sensitivity to the effects of alcohol in humans

21 January 2018

1 reference

Effects of naltrexone on alcohol sensitivity and genetic moderators of medication response: a double-blind placebo-controlled study

21 January 2018

1 reference

Pathway based analysis of genotypes in relation to alcohol dependence

21 January 2018

1 reference

[3H]naloxone binding in the human brain: alcoholism and the TaqI A D2 dopamine receptor polymorphism

21 January 2018

1 reference

Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model

21 January 2018

1 reference

Genetic analysis of the mu-opioid receptor in alcohol-dependent individuals

21 January 2018

1 reference

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

21 January 2018

1 reference

In search of causal variants: refining disease association signals using cross-population contrasts

21 January 2018

1 reference

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

21 January 2018

1 reference

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

21 January 2018

1 reference

Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

21 January 2018

1 reference

Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

21 January 2018

1 reference

Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis

21 January 2018

1 reference

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

21 January 2018

1 reference

Statistical power and significance testing in large-scale genetic studies

21 January 2018

1 reference

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

21 January 2018

1 reference

A missense mutation in human fatty acid amide hydrolase associated with problem drug use.

21 January 2018

1 reference

Association study of novel human serotonin 5-HT(1B) polymorphisms with alcohol dependence in Taiwanese Han.

21 January 2018

1 reference

Prediction of deleterious human alleles

21 January 2018

1 reference

Accessing genetic variation: genotyping single nucleotide polymorphisms

21 January 2018

1 reference

Genetical genomic determinants of alcohol consumption in rats and humans

21 January 2018

1 reference

Structure of the rat catechol-O-methyltransferase gene: separate promoters are used to produce mRNAs for soluble and membrane-bound forms of the enzyme

21 January 2018

1 reference

ADH2 gene polymorphisms are determinants of alcohol pharmacokinetics

21 January 2018

1 reference

Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism.

21 January 2018

1 reference

Genome-wide association studies of alcohol dependence and substance use disorders

21 January 2018

1 reference

The endogenous opioid system: a common substrate in drug addiction

21 January 2018

1 reference

ADH4 intronic variations are associated with alcohol dependence: results from an Italian case-control association study

21 January 2018

1 reference

Techniques patents for SNP genotyping

21 January 2018

1 reference

The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: studies of drug use and dependence in Caucasians.

21 January 2018

1 reference

Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes

21 January 2018

1 reference

A novel SNP in COMT is associated with alcohol dependence but not opiate or nicotine dependence: a case control study

21 January 2018

1 reference

Rare nonsynonymous exonic variants in addiction and behavioral disinhibition

21 January 2018

1 reference

Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world

21 January 2018

1 reference

Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.

21 January 2018

1 reference

A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.

21 January 2018

1 reference

Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants

21 January 2018

1 reference

Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach

21 January 2018

1 reference

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk

21 January 2018

1 reference

Identification of ADH4 as a novel and potential prognostic marker in hepatocellular carcinoma.

21 January 2018

1 reference

Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence

21 January 2018

1 reference

The role of acetylcholine in cocaine addiction.

21 January 2018

1 reference

Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence

21 January 2018

1 reference

Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence

21 January 2018

1 reference

Human class IV alcohol dehydrogenase: kinetic mechanism, functional roles and medical relevance

21 January 2018

1 reference

Human aldehyde dehydrogenase gene family.

21 January 2018

1 reference

A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia

21 January 2018

1 reference

Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

21 January 2018

1 reference

Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

21 January 2018

1 reference

Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample

21 January 2018

1 reference

Rare ADH variant constellations are specific for alcohol dependence

21 January 2018

1 reference

Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/ADB.12204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25603899%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference