(Q38330960)

2 September 2017

title

Modulatory effects of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation elicited by gp120. (English)

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2 September 2017

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ChEBI release 2020-05-28

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Lucia Lisi

1

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Pierluigi Navarra

object named as

Pierluigi Navarra

4

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Cinzia Dello Russo

object named as

Cinzia Dello Russo

5

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Andrea De Luca

object named as

Andrea De Luca

3

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author name string

Antonella Tramutola

2

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2 September 2017

language of work or name

English

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publication date

17 November 2011

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Journal of Neurochemistry

2 September 2017

published in

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2 September 2017

volume

120

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2 September 2017

issue

1

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2 September 2017

page(s)

106-114

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The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle

2 September 2017

cites work

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Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology

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Pretreatment with interferon-gamma protects microglia from oxidative stress via up-regulation of Mn-SOD.

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Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation

21 January 2018

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Diverging effects of cortistatin and somatostatin on the production and release of prostanoids from rat cortical microglia and astrocytes

21 January 2018

1 reference

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Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity

21 January 2018

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Expression and identification of immunological activities of the HIV-gp120N-human interferon gamma fusion protein.

21 January 2018

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Agonist-induced internalization of CC chemokine receptor 5 as a mechanism to inhibit HIV replication

21 January 2018

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G-protein-coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity.

21 January 2018

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Influence of IFN-gamma and its receptors in human breast cancer

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Clinical use of CCR5 inhibitors in HIV and beyond

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Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

21 January 2018

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Thinking about HIV: the intersection of virus, neuroinflammation and cognitive dysfunction

21 January 2018

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Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages

21 January 2018

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Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis

21 January 2018

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The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages.

21 January 2018

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The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes

21 January 2018

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HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes

21 January 2018

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Macrophage inflammatory protein-1

21 January 2018

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A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitors

21 January 2018

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Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection

21 January 2018

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Elevated expression of IFN-gamma in the HIV-1 infected brain

21 January 2018

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Erythropoietin exerts anti-apoptotic effects on rat microglial cells in vitro.

21 January 2018

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Chemokine blockers--therapeutics in the making?

21 January 2018

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CNS inflammation and macrophage/microglial biology associated with HIV-1 infection.

21 January 2018

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10.1111/J.1471-4159.2011.07549.X

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

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