(Q38341513)

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Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

2 references

Europe PubMed Central

13 November 2020

Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

cell surface receptor

1 reference

31 July 2019

pattern recognition receptors

1 reference

3 August 2019

1 reference

12 September 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

transport protein

1 reference

28 November 2019

membrane protein

1 reference

15 December 2019

inflammasome complex

1 reference

based on heuristic

inferred from title

1 reference

13 November 2020

Claudio Cardinali

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Maria Beatrice Morelli

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Massimo Nabissi

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Giorgio Santoni

1

1 reference

Europe PubMed Central

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29 February 2020

Matteo Santoni

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Consuelo Amantini

6

1 reference

Europe PubMed Central

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29 February 2020

publication date

3 February 2015

9 references

31 July 2019

3 August 2019

12 September 2019

12 October 2019

18 October 2019

28 November 2019

15 December 2019

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

13 November 2020

Journal of Neuroinflammation

9 references

31 July 2019

3 August 2019

12 September 2019

12 October 2019

18 October 2019

28 November 2019

15 December 2019

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

13 November 2020

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

21

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Europe PubMed Central

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29 February 2020

copyright license

Creative Commons Attribution

8 references

31 July 2019

3 August 2019

12 September 2019

12 October 2019

18 October 2019

28 November 2019

15 December 2019

13 November 2020

copyright status

0 references

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IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection

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TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide

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TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation

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Cell volume regulation modulates NLRP3 inflammasome activation

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6 September 2017

Inflammasomes and their roles in health and disease

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6 September 2017

The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels

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6 September 2017

Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction

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6 September 2017

Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis

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6 September 2017

Neurogenic Inflammation – The Peripheral Nervous System’s Role in Host Defense and Immunopathology

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6 September 2017

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

1 reference

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6 September 2017

NLRs, inflammasomes, and viral infection

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6 September 2017

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

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6 September 2017

Inflammasomes in health and disease

1 reference

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6 September 2017

The role of TRPA1 in visceral inflammation and pain

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6 September 2017

The inflammasome: an integrated view

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6 September 2017

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

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6 September 2017

Painful pathways induced by TLR stimulation of dorsal root ganglion neurons

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6 September 2017

The transient receptor potential family of ion channels

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TRPV channels in tumor growth and progression.

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6 September 2017

Mitochondrial ROS fuel the inflammasome

1 reference

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

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Emerging concepts for the role of TRP channels in the cardiovascular system

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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

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Lipopolysaccharide from Porphyromonas gingivalis sensitizes capsaicin-sensitive nociceptors

1 reference

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A role for mitochondria in NLRP3 inflammasome activation

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Sodium overload and water influx activate the NALP3 inflammasome

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Toll-like receptor 7 mediates pruritus

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Tumor necrosis factor-α induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions

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TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.

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TRPV1 Function in Health and Disease

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Inflammasome-Mediated Autoinflammatory Disorders

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

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Intracellular toll-like receptors

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The inflammasomes

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Pattern recognition receptors and inflammation

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Transient receptor potential channelopathies

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Interleukin 18 in the CNS.

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Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels

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The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome

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6 September 2017

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders.

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The role of transient receptor potential channels in kidney disease

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Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction

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6 September 2017

Function and regulation of TRPP2 at the plasma membrane

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Physiology of cell volume regulation in vertebrates.

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6 September 2017

Nociceptors are interleukin-1beta sensors

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Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity

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6 September 2017

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology

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6 September 2017

Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1.

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6 September 2017

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

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6 September 2017

The Nalp3 inflammasome is essential for the development of silicosis

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6 September 2017

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

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6 September 2017

Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures

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A molecular platform in neurons regulates inflammation after spinal cord injury

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6 September 2017

NLRs at the intersection of cell death and immunity

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6 September 2017

Nod-like proteins in inflammation and disease.

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6 September 2017

The inflammasome: a danger sensing complex triggering innate immunity

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6 September 2017

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

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6 September 2017

Transient receptor potential channels in Alzheimer's disease.

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6 September 2017

TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?

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6 September 2017

The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7.

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6 September 2017

Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli

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6 September 2017

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

1 reference

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6 September 2017

Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism

1 reference

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6 September 2017

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy

1 reference

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6 September 2017

The role of TRP channels in oxidative stress-induced cell death

1 reference

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6 September 2017

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

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6 September 2017

Neuronal eotaxin and the effects of CCR3 antagonist on airway hyperreactivity and M2 receptor dysfunction

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6 September 2017

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

1 reference

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6 September 2017

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells

1 reference

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6 September 2017

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

TRP channels as cellular sensors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

The mechanism of cell membrane repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

6 September 2017

Characterization of TRPM8-like channels activated by the cooling agent icilin in the macrophage cell line RAW 264.7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Capsaicin promotes a more aggressive gene expression phenotype and invasiveness in null-TRPV1 urothelial cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Chemical probing reveals insights into the signaling mechanism of inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

TRPV2 has a pivotal role in macrophage particle binding and phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Capsaicin-induced apoptosis of glioma cells is mediated by TRPV1 vanilloid receptor and requires p38 MAPK activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Contribution of TRPM8 channels to cold transduction in primary sensory neurons and peripheral nerve terminals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

Co-activation of P2Y2 receptor and TRPV channel by ATP: implications for ATP induced pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

mRNA distribution analysis of human TRPC family in CNS and peripheral tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

14 September 2017

The changes in human synovial fluid osmolality associated with traumatic or mechanical abnormalities of the knee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

27 September 2017

Porphyromonas gingivalis neutrophil manipulation: risk factor for periodontitis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

23 June 2018

The pharmacology of TRP channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

23 June 2018

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

23 June 2018

Spatial interactions between dendritic cells and sensory nerves in allergic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

23 June 2018

Substance P selectively activates TNF-alpha gene expression in murine mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

23 June 2018

Transient receptor potential ankyrin 1 receptor stimulation by hydrogen peroxide is critical to trigger pain during monosodium urate-induced inflammation in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Human astrocytes express a novel NLRP2 inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Spreading depression triggers headache by activating neuronal Panx1 channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Degraded mitochondrial DNA is a newly identified subtype of the damage associated molecular pattern (DAMP) family and possible trigger of neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Intracellular acidification evoked by moderate extracellular acidosis attenuates transient receptor potential V1 (TRPV1) channel activity in rat dorsal root ganglion neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Inflammasome activation in reperfusion injury: friendly fire on myocardial infarction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Association of transient receptor potential canonical type 3 (TRPC3) channel transcripts with proinflammatory cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322456

31 August 2018

PW02-035 - A role for thermo-TRP channels in innate immunity?

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0239-2

21 January 2018

LPS sensitizes TRPV1 via activation of TLR4 in trigeminal sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human monocyte interleukin-1beta posttranslational processing. Evidence of a volume-regulated response

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate immunity: inflammasome triggered by cell swelling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell volume in cell proliferation and apoptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transient receptor potential vanilloid receptor 1 and toll-like receptor 4 in aggressive periodontitis and in chronic periodontitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Participation of the TRPV1 receptor in the development of acute gout attacks

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pragmatic target discovery from novel gene to functionally defined drug target: the interleukin-1 story

1 reference

https://pubmed.ncbi.nlm.nih.gov/25644504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12974-015-0239-2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Dimensions Publication ID

0 references

release_yep472m2frcmblgzznzg7xnebi

1 reference

https://api.fatcat.wiki/v0/release/yep472m2frcmblgzznzg7xnebi

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25644504%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

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