(Q38342368)

2 September 2017

DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation (English)

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2 September 2017

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Snezana Milutinovic

1

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2 September 2017

Shelley E Brown

series ordinal

2

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2 September 2017

Qianli Zhuang

series ordinal

3

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2 September 2017

Moshe Szyf

series ordinal

4

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2 September 2017

language of work or name

English

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publication date

15 April 2004

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Journal of Biological Chemistry

2 September 2017

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2 September 2017

279

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2 September 2017

27

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2 September 2017

27915-27927

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CpG methylation, chromatin structure and gene silencing-a three-way connection

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

DNA methylation patterns. Formation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflower

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

A beta vasoactivity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

A conserved 3'-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Targeting DNA methylation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Inhibition of DNA methyltransferase inhibits DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Utilization of antisense oligonucleotides to study the role of 5-cytosine DNA methyltransferase in cellular transformation and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

High sensitivity mapping of methylated cytosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Histone deacetylase inhibitor activates the p21/WAF1/Cip1 gene promoter through the Sp1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Methyl-CpG-binding protein MeCP2 represses Sp1-activated transcription of the human leukosialin gene when the promoter is methylated

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

MCAF mediates MBD1-dependent transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

5-azaC treatment enhances expression of transforming growth factor-beta receptors through down-regulation of Sp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Sp1- and Krüppel-like transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Sp1, but not Sp3, functions to mediate promoter activation by TGF-beta through canonical Sp1 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin-dependent kinase inhibitor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Towards a pharmacology of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

Induction of Tumors in Mice by Genomic Hypomethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312823200

21 January 2018

Identifiers

DOI

10.1074/JBC.M312823200

1 reference

2 September 2017

1 reference