(Q38345608)

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Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.

scientific article published on 18 March 2010

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Europe PubMed Central

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20 January 2020

Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells (English)

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Europe PubMed Central

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20 January 2020

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Andreas Lennartsson

6

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Europe PubMed Central

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20 January 2020

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K Vidovic

1

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20 January 2020

E Svensson

2

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20 January 2020

B Nilsson

3

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20 January 2020

B Thuresson

4

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20 January 2020

T Olofsson

5

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20 January 2020

U Gullberg

7

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20 January 2020

publication date

18 March 2010

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20 January 2020

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20 January 2020

24

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20 January 2020

5

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20 January 2020

992-1000

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20 January 2020

Wilms tumor and the WT1 gene

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

WT1 proteins: functions in growth and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Role of the WT1 tumor suppressor in murine hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Constitutive expression of the Wilms' tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF).

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

The IRF family transcription factors in immunity and oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of cytokine-stimulated CD34+ human marrow cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Prognostically useful gene-expression profiles in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Gene expression profiling of CD34+ cells identifies a molecular signature of chronic myeloid leukemia blast crisis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Wilms' tumor 1 and signal transducers and activators of transcription 3 synergistically promote cell proliferation: a possible mechanism in sporadic Wilms' tumor

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Positive histone marks are associated with active transcription from a methylated ICSBP/IRF8 gene

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Molecular basis for modulation of biological function by alternate splicing of the Wilms' tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

21 January 2018

Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

7 January 2021

based on heuristic

inferred from DOI database lookup

A tumor suppressor and oncogene: the WT1 story.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.33

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/LEU.2010.33

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20237505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20237505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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