(Q38351396)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Identification of target genes of the p16INK4A-pRB-E2F pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Heiko Muller

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

Richard Vernell

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

language of work or name

English

0 references

publication date

15 August 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

46124-46137

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Retinoblastoma protein partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Regulation of cell proliferation by the E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Sibling rivalry in the E2F family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Expression monitoring by hybridization to high-density oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Pocket protein-independent repression of urokinase-type plasminogen activator and plasminogen activator inhibitor 1 gene expression by E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Direct coupling of the cell cycle and cell death machinery by E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Gene expression changes in response to E2F1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The RB and p53 pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

NFAT signaling: choreographing the social lives of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Pathways of apoptosis in lymphocyte development, homeostasis, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

WNT signaling and lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The retinoblastoma tumour suppressor in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The Fanconi anaemia/BRCA pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

VEGF and the quest for tumour angiogenesis factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Feedback control of intercellular signalling in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Signal transduction by the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Novel alternative PBX3 isoforms in leukemia cells with distinct interaction specificities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The SIL gene is required for mouse embryonic axial development and left-right specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

In search of a function for the TIS21/PC3/BTG1/TOB family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Expression of rat BTG(3) gene, Rbtg3, is regulated by redox changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The Mad protein family links transcriptional repression to cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

STAT3 down-regulates the expression of cyclin D during liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Chemical synthesis of a peptide fragment of thymopoietin II that induces selective T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

BTG gene expression in the p53-dependent and -independent cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

Thymopoietin-induced acquisition of responsiveness to T cell mitogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304930200

21 January 2018

Identifiers

DOI

10.1074/JBC.M304930200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12923195%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference