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Mitochondrial reactive oxygen species and cancer.
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Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
review article
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Europe PubMed Central
title
Mitochondrial reactive oxygen species and cancer
(English)
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stated in
Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
main subject
reactive oxygen species
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inferred from title
author
Lucas B Sullivan
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
author name string
Navdeep S Chandel
series ordinal
2
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Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
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English
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publication date
28 November 2014
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Europe PubMed Central
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4323058
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retrieved
29 February 2020
published in
Cancer & Metabolism
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Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
volume
2
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Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
page(s)
17
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Europe PubMed Central
PMC publication ID
4323058
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
exact match
https://scigraph.springernature.com/pub.10.1186/2049-3002-2-17
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Structure, mechanism and regulation of peroxiredoxins
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
The phosphoinositide 3-kinase pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Reversible inactivation of the tumor suppressor PTEN by H2O2
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Cells depleted of mitochondrial DNA (rho0) yield insight into physiological mechanisms
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
NADPH oxidase: an update
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Oxidants, antioxidants, and the degenerative diseases of aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Production of large amounts of hydrogen peroxide by human tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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6 September 2017
Oxygen radicals and human disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
HIF-dependent antitumorigenic effect of antioxidants in vivo
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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14 September 2017
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
retrieved
14 September 2017
A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
retrieved
14 September 2017
Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
retrieved
14 September 2017
A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
retrieved
14 September 2017
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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23 June 2018
Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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23 June 2018
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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23 June 2018
Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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31 August 2018
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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31 August 2018
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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31 August 2018
JunD reduces tumor angiogenesis by protecting cells from oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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31 August 2018
Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
retrieved
31 August 2018
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323058
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31 August 2018
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25671107
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/2049-3002-2-17
1 reference
stated in
Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Dimensions Publication ID
1035720907
0 references
PMC publication ID
4323058
1 reference
stated in
Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed publication ID
25671107
1 reference
stated in
Europe PubMed Central
PMC publication ID
4323058
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25671107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
ResearchGate publication ID
272191137
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