(Q38352576)

2 September 2017

Properties of and substrate determinants for the exonuclease activity of human apurinic endonuclease Ape1. (English)

1 reference

2 September 2017

David M Wilson

1

1 reference

PubMed ID

12860125

2 September 2017

language of work or name

English

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publication date

1 July 2003

1 reference

Journal of Molecular Biology

2 September 2017

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2 September 2017

330

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2 September 2017

5

1 reference

2 September 2017

1027-1037

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Instability and decay of the primary structure of DNA

2 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Recent progress in the biology, chemistry and structural biology of DNA glycosylases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Mutagenesis by apurinic/apyrimidinic sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

7 January 2021

Life without DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Mammalian base excision repair and DNA polymerase beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Structure and function of mammalian DNA ligases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

XRCC1 keeps DNA from getting stranded

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Removal of 3'-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Effects of Ape1 overexpression on cellular resistance to DNA-damaging and anticancer agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

7 January 2021

An APE that proofreads

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

7 January 2021

The 3' 5' exonucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

A quantitative model of human DNA base excision repair. I. Mechanistic insights

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Human apurinic/apyrimidinic endonuclease is processive

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

p53 Modulates the exonuclease activity of Werner syndrome protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Kinetic mechanism of the 3'-->5' proofreading exonuclease of DNA polymerase III. Analysis by steady state and pre-steady state methods

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Complexities of the DNA base excision repair pathway for repair of oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

AP endonuclease 1 has no biologically significant 3(')-->5(')-exonuclease activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Cellular roles of dna topoisomerases: a molecular perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Repair of oxidative damage to DNA: enzymology and biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Structure and function of apurinic/apyrimidinic endonucleases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Rates of base excision repair are not solely dependent on levels of initiating enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Substrate specificity of the p53-associated 3'-5' exonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Exonucleolytic proofreading by p53 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Characterization of the human and mouse WRN 3'-->5' exonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Excision of mismatched nucleotides from DNA: a potential mechanism for enhancing DNA replication fidelity by the wild-type p53 protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Base excision repair of oxidative DNA damage activated by XPG protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900712-5

10.1016/S0022-2836(03)00712-5

7 January 2021

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

12860125