(Q38353791)

English

Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Levon Khachigian

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

Mary M Kavurma

1

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Levon M Khachigian

2

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

language of work or name

0 references

publication date

9 June 2003

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

278

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

35

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

32537-32543

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Molecular determinants of atherosclerotic plaque vulnerability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Sp1 phosphorylation regulates apoptosis via extracellular FasL-Fas engagement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Regulation of CDK/cyclin complexes during the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Cell-cycle inhibitors: three families united by a common cause

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

New functional activities for the p21 family of CDK inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Cyclin-binding motifs are essential for the function of p21CIP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Role of zinc-finger proteins Sp1 and zif268/egr-1 in transcriptional regulation of the human synaptobrevin II gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Zinc finger transcription factors mediate high constitutive platelet-derived growth factor-B expression in smooth muscle cells derived from aortae of newborn rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Activation of p21(WAF1/Cip1) transcription through Sp1 sites by histone deacetylase inhibitor apicidin: involvement of protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305650200

21 January 2018

Identifiers

10.1074/JBC.M305650200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12796485%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38353791&oldid=1509457775"