(Q38358055)

2 September 2017

1 reference

title

Gene of the month: PIK3CA. (English)

1 reference

2 September 2017

K Lai

1

1 reference

2 September 2017

M C Killingsworth

series ordinal

2

1 reference

2 September 2017

C S Lee

series ordinal

3

1 reference

2 September 2017

language of work or name

English

0 references

publication date

16 February 2015

1 reference

Journal of Clinical Pathology

2 September 2017

published in

1 reference

2 September 2017

volume

68

1 reference

2 September 2017

issue

4

1 reference

2 September 2017

page(s)

253-257

1 reference

Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene.

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Prospects for phosphoinositide 3-kinase inhibition as a cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Phosphoinositide 3-kinases as accelerators and brakes of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Genetic deregulation of the PIK3CA oncogene in oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Molecular pathways in head and neck cancer: EGFR, PI3K, and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Regulation and cellular functions of class II phosphoinositide 3-kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Oncogenic PI3K deregulates transcription and translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Class I PI3K in oncogenic cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutations in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Combined mutational analysis of RAS, BRAF, PIK3CA, and TP53 genes in Taiwanese patients with oral squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Novel mutant-enriched sequencing identified high frequency of PIK3CA mutations in pharyngeal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Sequencing the head and neck cancer genome: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Absence of hotspot mutations in exons 9 and 20 of the PIK3CA gene in human oral squamous cell carcinoma in the Greek population

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Biological basis for increased sensitivity to radiation therapy in HPV-positive head and neck cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Oncogenic mutations as predictive factors in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Oncogenic PIK3CA mutations in colorectal cancers and polyps

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutation and histological type in breast carcinoma: high frequency of mutations in lobular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutation associates with improved outcome in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Evaluation of the association of PIK3CA mutations and PTEN loss with efficacy of trastuzumab therapy in metastatic breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Frequent mutational activation of the PI3K-AKT pathway in trastuzumab-resistant breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PI3K pathway activation results in low efficacy of both trastuzumab and lapatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA mutations are a predictor of docetaxel plus epirubicin neoadjuvant chemotherapy clinical efficacy in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

The significance of autophagy in colorectal cancer pathogenesis and implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Akt and autophagy cooperate to promote survival of drug-resistant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2015-202885

10.1136/JCLINPATH-2015-202885

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference