(Q38362682)

2 September 2017

title

Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein (English)

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2 September 2017

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L McConlogue

1

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2 September 2017

F Castellano

2

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2 September 2017

C deWit

3

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2 September 2017

D Schenk

4

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2 September 2017

W A Maltese

5

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2 September 2017

language of work or name

English

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publication date

1 January 1996

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

271

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2 September 2017

issue

3

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2 September 2017

page(s)

1343-1348

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

2 September 2017

cites work

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

21 January 2018

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Inhibition of beta-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

21 January 2018

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

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Beta-amyloid precursor protein cleavage by a membrane-bound protease

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

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Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway

21 January 2018

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The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

21 January 2018

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Cell-type and amyloid precursor protein-type specific inhibition of A beta release by bafilomycin A1, a selective inhibitor of vacuolar ATPases

21 January 2018

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The vacuolar H(+)-ATPase inhibitor bafilomycin A1 differentially affects proteolytic processing of mutant and wild-type beta-amyloid precursor protein

21 January 2018

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Rab proteins and the road maps for intracellular transport

21 January 2018

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GTPases: multifunctional molecular switches regulating vesicular traffic

21 January 2018

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Rab GTPases: master regulators of membrane trafficking

21 January 2018

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GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex

21 January 2018

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The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

21 January 2018

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21 January 2018

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A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments

21 January 2018

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Rab1 and Ca2+ are required for the fusion of carrier vesicles mediating endoplasmic reticulum to Golgi transport

21 January 2018

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The small GTP-binding protein rab6 functions in intra-Golgi transport

21 January 2018

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A cytosolic complex of p62 and rab6 associates with TGN38/41 and is involved in budding of exocytic vesicles from the trans-Golgi network

21 January 2018

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Isoprenylation of Rab proteins possessing a C-terminal CaaX motif

21 January 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

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Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease.

21 January 2018

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rasH mutants deficient in GTP binding

21 January 2018

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The ras protein family: evolutionary tree and role of conserved amino acids

21 January 2018

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Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag

21 January 2018

1 reference

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Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins

21 January 2018

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Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane

21 January 2018

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Protein transport to the dendritic plasma membrane of cultured neurons is regulated by rab8p

21 January 2018

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

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Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

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Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

Activation of protein kinase C increases the extracellular release of the transmembrane amyloid protein precursor of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

Inhibition of beta-amyloid production by activation of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.3.1343

21 January 2018

Identifiers

DOI

10.1074/JBC.271.3.1343

1 reference

2 September 2017

1 reference